Renal cell carcinoma history and symptoms: Difference between revisions

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The common symptoms of renal cell carcinoma include [[hematuria]], [[flank pain]], palpable [[abdominal mass]], [[hypertension]], [[hypercalcemia]], [[flushing]], [[fever]], [[fatigue]], [[weight loss]], [[anorexia]], and [[muscle atrophy]].
The common symptoms of renal cell carcinoma include [[hematuria]], [[flank pain]], palpable [[abdominal mass]], [[hypertension]], [[hypercalcemia]], [[flushing]], [[fever]], [[fatigue]], [[weight loss]], [[anorexia]], and [[muscle atrophy]].


==Symptoms==
Patients with renal cell carcinoma typically present at 60-70 years of age. The most common diagnosis of renal cell carcinoma is based on the incidental finding; whereby most patients are asymptomatic.
Symptoms are often classified as local and systemic.
===Local Symptoms===
The presence of local signs is considered a poor prognostic marker<ref name="pmid19269025">{{cite journal| author=Rini BI, Campbell SC, Escudier B| title=Renal cell carcinoma. | journal=Lancet | year= 2009 | volume= 373 | issue= 9669 | pages= 1119-32 | pmid=19269025 | doi=10.1016/S0140-6736(09)60229-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19269025  }} </ref>. Common local symptoms are listed below<ref name="pmid19269025">{{cite journal| author=Rini BI, Campbell SC, Escudier B| title=Renal cell carcinoma. | journal=Lancet | year= 2009 | volume= 373 | issue= 9669 | pages= 1119-32 | pmid=19269025 | doi=10.1016/S0140-6736(09)60229-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19269025  }} </ref>:
*[[Hematuria]]
*[[Flank pain]]
*Palpable [[abdominal mass]]
===Systemic Symptoms===
The presence of systemic symptoms is mostly due to the presence of a [[paraneoplastic syndrome]], mostly due to the presence of parathyroid-related protein (PTHrp) or a [[metastasis]].<ref name="pmid19269025">{{cite journal| author=Rini BI, Campbell SC, Escudier B| title=Renal cell carcinoma. | journal=Lancet | year= 2009 | volume= 373 | issue= 9669 | pages= 1119-32 | pmid=19269025 | doi=10.1016/S0140-6736(09)60229-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19269025  }} </ref> Common systemic symptoms are listed below<ref name="pmid19269025">{{cite journal| author=Rini BI, Campbell SC, Escudier B| title=Renal cell carcinoma. | journal=Lancet | year= 2009 | volume= 373 | issue= 9669 | pages= 1119-32 | pmid=19269025 | doi=10.1016/S0140-6736(09)60229-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19269025  }} </ref>:
*[[Hypertension]] ([[renin]] secretion)
*[[Hypercalcemia]] (PTHrp secretion)
*[[Flushing]] (Erythroprotein secretion)
*[[Fever]]
*[[Fatigue]]
*[[Weight loss]]
*[[Anorexia]]
*[[Muscle atrophy]]
*
==History and Symptoms==
==History and Symptoms==
*The majority of patients with [disease name] are asymptomatic.
*The majority of patients with [disease name] are asymptomatic.

Revision as of 15:52, 26 July 2018


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

The common symptoms of renal cell carcinoma include hematuria, flank pain, palpable abdominal mass, hypertension, hypercalcemia, flushing, fever, fatigue, weight loss, anorexia, and muscle atrophy.

History and Symptoms

  • The majority of patients with [disease name] are asymptomatic.

OR

  • The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
  • Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History

Patients with [disease name]] may have a positive history of:

  • [History finding 1]
  • [History finding 2]
  • [History finding 3]

Common Symptoms

Common symptoms of [disease] include:

Less Common Symptoms

Less common symptoms of [disease name] include:

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