Hereditary spherocytosis surgery: Difference between revisions
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==Surgery== | ==Surgery== | ||
* Splenectomy is the definitive treatment for HS. <sup>[3]</sup> Except in the unusual autosomal recessive variant of HS, splenectomy usually eliminates hemolysis and the associated signs and symptoms. <sup>[4]</sup> Interestinagly, splenectomy does little to correct the cytoskeletal membrane defects of HS; an atomic force microscopy study by Li et al found that after splenectomy, erythrocytes were larger but still spheroidal-shaped, with a disorganized membrane ultrastructure and reduced surface particle size. | |||
==References== | ==References== |
Revision as of 11:35, 27 July 2018
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Overview
Surgery
- Splenectomy is the definitive treatment for HS. [3] Except in the unusual autosomal recessive variant of HS, splenectomy usually eliminates hemolysis and the associated signs and symptoms. [4] Interestinagly, splenectomy does little to correct the cytoskeletal membrane defects of HS; an atomic force microscopy study by Li et al found that after splenectomy, erythrocytes were larger but still spheroidal-shaped, with a disorganized membrane ultrastructure and reduced surface particle size.