Pseudotumor cerebri pathophysiology

Pseudotumor cerebri Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating pseudotumor cerebri from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Interventions
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Pseudotumor cerebri pathophysiology On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Pseudotumor cerebri pathophysiology All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Pseudotumor cerebri pathophysiology
CDC on Pseudotumor cerebri pathophysiology
Pseudotumor cerebri pathophysiology in the news
Blogs on Pseudotumor cerebri pathophysiology
Directions to Hospitals Treating Psoriasis
Risk calculators and risk factors for Pseudotumor cerebri pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Pathophysiology

Pathogenesis

The exact pathogenesis of pseudotumor cerebri is not completely understood. Idiopathic intracranial hypertension or pseudotumor cerebri is defined by the symptoms of increased intracranial pressure without any evidence of tumor.(1uptodate)

Any theory regarding the pathophysiology of this disease should explain the following statements:

• High incidence rate in women with childbearing age
• Reduced conductance to CSF outflow(25 wall)
• Normal ventricle size and lack of hydrocephalus(26 wall)
• No evidence of cerebral edema(27 wall)

Some of the these theories are:

• Cerebral venous outflow abnormalities
• increased CSF outflow resistance
• obesity.(89 uptodate)
• Vitamin A intoxication(39 uptodate)
• Sleep apnea(18uptodate)
• Sex hormones(127 uptodate)

Genetics

[Disease name] is transmitted in [mode of genetic transmission] pattern.

OR

Genes involved in the pathogenesis of [disease name] include:

• [Gene1]
• [Gene2]
• [Gene3]

OR

The development of [disease name] is the result of multiple genetic mutations such as:

• [Mutation 1]
• [Mutation 2]
• [Mutation 3]

Gross Pathology

On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

Microscopic Pathology

On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].