Pseudotumor cerebri causes: Difference between revisions

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Created page with "__NOTOC__ {{Pseudotumor cerebri}} {{CMG}}; {{AE}} ==Overview== Disease name] may be caused by [cause1], [cause2], or [cause3]. OR Common causes of [disease] include [cause..."
 
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{{CMG}}; {{AE}}  
{{CMG}}; {{AE}}  
==Overview==
==Overview==
Disease name] may be caused by [cause1], [cause2], or [cause3].
OR
Common causes of [disease] include [cause1], [cause2], and [cause3].
OR
The most common cause of [disease name] is [cause 1]. Less common causes of [disease name] include [cause 2], [cause 3], and [cause 4].
OR
The cause of [disease name] has not been identified. To review risk factors for the development of [disease name], click [[Pericarditis causes#Overview|here]].
==Causes==
==Causes==
===Life-threatening Causes===
* Increased production of CSF and reduced resorption: Normal CSF flow involves production at the [[Choroid plexus|choroid plexuses]] and absorption at the cranial and [[spinal nerve]] root arachnoid villi and granulations. Impaired CSF absorption at the [[superior sagittal sinus]] or along the spinal nerve roots could therefore explain IIH and has been documented in 75-100% of IIH patients. Permeability along the blood-CSF barrier varies, producing an increasing [[oncotic pressure]] gradient between the CSF and venous system in a [[rostral]] to [[caudal]] progression.  It is speculated that variations in this oncotic pressure contribute to or impede CSF absorption.
*Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. There are no life-threatening causes of [[disease name]], however complications resulting from untreated [[disease name]] is common.
* obesity.(89 uptodate): Some evidences suggest that onesity can increase intra abdominal and intra cranial pressure and have a role in pathogenesis of IHH. (106 uptodate) In a study on 7 obese women with IHH it was seen that weith loss improved their symptoms.(107 uptodate) In the other hand higher level of leptin (a protein released from adipose tissue) was found in IHH patiets.(125)
*Life-threatening causes of [symptom/manifestation] include [cause1], [cause2], and [cause3].
* Vitamin A intoxication: There are some evidences of higher serum and CSF level of vitamin A, retinol and retinol binding protein can be related to IHH pathogenesis.(116-118)
*[Cause] is a life-threatening cause of [disease].
* Sleep apnea: Sleep apnea can cause hypercarbia which can result in vasodilation and elevated intacranial pressure (74 uptodate)
 
* Sex hormones: In one study regarding IIH etiology which was done on 8 men with this disease, Four of them had abnormal FSH and LH level, 2 of them had estradiol abnormalities and seven of them had reduced testosterone level.(127 uptodate)
===Common Causes===
Common causes of [disease name] may include:
*[Cause1]
*[Cause2]
*[Cause3]
 
 
OR
 
 
*[Disease name] is caused by an infection with [pathogen name].
*[Pathogen name] is caused by [pathogen name].
 
===Less Common Causes===
Less common causes of [disease name] include:
*[Cause1]
*[Cause2]
*[Cause3]
 
===Genetic Causes===
*[Disease name] is caused by a mutation in the [gene name] gene.
 
===Causes by Organ System===
 
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|-
|}
 


===Causes in Alphabetical Order===
List the causes of the disease in alphabetical order:
<div style="-moz-column-count:3; column-count:3;">
* Cause 1
* Cause 2
* Cause 3
* Cause 4
* Cause 5
* Cause 6
* Cause 7
* Cause 8
* Cause 9
* Cause 10
</div>


==References==
==References==

Revision as of 17:29, 27 July 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Causes

  • Increased production of CSF and reduced resorption: Normal CSF flow involves production at the choroid plexuses and absorption at the cranial and spinal nerve root arachnoid villi and granulations. Impaired CSF absorption at the superior sagittal sinus or along the spinal nerve roots could therefore explain IIH and has been documented in 75-100% of IIH patients. Permeability along the blood-CSF barrier varies, producing an increasing oncotic pressure gradient between the CSF and venous system in a rostral to caudal progression. It is speculated that variations in this oncotic pressure contribute to or impede CSF absorption.
  • obesity.(89 uptodate): Some evidences suggest that onesity can increase intra abdominal and intra cranial pressure and have a role in pathogenesis of IHH. (106 uptodate) In a study on 7 obese women with IHH it was seen that weith loss improved their symptoms.(107 uptodate) In the other hand higher level of leptin (a protein released from adipose tissue) was found in IHH patiets.(125)
  • Vitamin A intoxication: There are some evidences of higher serum and CSF level of vitamin A, retinol and retinol binding protein can be related to IHH pathogenesis.(116-118)
  • Sleep apnea: Sleep apnea can cause hypercarbia which can result in vasodilation and elevated intacranial pressure (74 uptodate)
  • Sex hormones: In one study regarding IIH etiology which was done on 8 men with this disease, Four of them had abnormal FSH and LH level, 2 of them had estradiol abnormalities and seven of them had reduced testosterone level.(127 uptodate)


References

Template:WH Template:WS

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