Thrombocytopenia differential diagnosis: Difference between revisions
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
{| class="wikitable" | {| class="wikitable" | ||
!Category | ! rowspan="2" |Category | ||
!Disease | ! rowspan="2" |Disease | ||
!History and symptoms | ! rowspan="2" |History and symptoms | ||
! colspan="3" |Laboratory findings | ! colspan="3" |Laboratory findings | ||
!Pathology | ! rowspan="2" |Pathology | ||
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| | |[[White blood cells|WBC]] changes | ||
|[[Red blood cell|RBC]] changes | |||
|WBC changes | |||
|RBC changes | |||
|other findings | |other findings | ||
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| rowspan="2" |'''Cardiovascular''' | | rowspan="2" |'''Cardiovascular''' | ||
|[[endocarditis]] | |[[endocarditis]] | ||
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|<nowiki>+/↑</nowiki> | |||
|<nowiki>-</nowiki> | |||
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| | * ↑ [[Erythrocyte sedimentation rate|ESR]] | ||
| | * ↑ [[Rheumatoid factor|RF]], [[Blood urea nitrogen|BUN]] and [[Creatinine|Cr]] may also be present | ||
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Revision as of 17:17, 28 July 2018
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Thrombocytopenia Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Thrombocytopenia differential diagnosis On the Web |
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American Roentgen Ray Society Images of Thrombocytopenia differential diagnosis |
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Risk calculators and risk factors for Thrombocytopenia differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Farbod Zahedi Tajrishi, M.D.
Overview
Thrombocytopenia has a broad range of potential causes. While a good history and physical examination can be helpful to diagnose some of these causes such as drug-induced thrombocytopenia, they usually don't suffice and further evaluation is often needed. There are also some useful points that may guide the physician to an appropriate diagnosis. For example, asymptomatic, isolated thrombocytopenia most probably suggests ITP, while thrombocytopenia in critically ill, hospitalized patients is usually suggestive of iatrogenic causes (eg. dilution), platelet consumption, bone marrow suppression from infection/sepsis, or even drug-induced thrombocytopenia. One should consider however, that a wide variety of other conditions such as autoimmune disorders, nutrient deficiencies, thrombotic microangiopathies could all as well cause thrombocytopenia.