Hydronephrosis natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
Common complications of hydronephrosis include infections, | Common complications of hydronephrosis include infections, hyperkalemia, metabolic acidosis, and distal renal tubular acidosis, hypertension and renal failure. | ||
Prognosis is generally excellent, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%. | Prognosis is generally excellent, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%. | ||
==Natural History, Complications, and Prognosis== | ==Natural History, Complications, and Prognosis== | ||
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===Complications=== | ===Complications=== | ||
*Common complications of hydronephrosis include:<ref name="pmid3565506">{{cite journal |vauthors=Kozeny GA, Hurley RM, Vertuno LL, Bansal VK, Zeller WP, Hano JE |title=Hypertension, mineralocorticoid-resistant hyperkalemia, and hyperchloremic acidosis in an infant with obstructive uropathy |journal=Am. J. Nephrol. |volume=6 |issue=6 |pages=476–81 |date=1986 |pmid=3565506 |doi=10.1159/000167258 |url=}}</ref><ref name="pmid8558697">{{cite journal |vauthors=Chandar J, Abitbol C, Zilleruelo G, Gosalbez R, Montané B, Strauss J |title=Renal tubular abnormalities in infants with hydronephrosis |journal=J. Urol. |volume=155 |issue=2 |pages=660–3 |date=February 1996 |pmid=8558697 |doi= |url=}}</ref><ref name="pmid18295269">{{cite journal |vauthors=Lee JH, Choi HS, Kim JK, Won HS, Kim KS, Moon DH, Cho KS, Park YS |title=Nonrefluxing neonatal hydronephrosis and the risk of urinary tract infection |journal=J. Urol. |volume=179 |issue=4 |pages=1524–8 |date=April 2008 |pmid=18295269 |doi=10.1016/j.juro.2007.11.090 |url=}}</ref> | *Common complications of hydronephrosis include:<ref name="pmid3565506">{{cite journal |vauthors=Kozeny GA, Hurley RM, Vertuno LL, Bansal VK, Zeller WP, Hano JE |title=Hypertension, mineralocorticoid-resistant hyperkalemia, and hyperchloremic acidosis in an infant with obstructive uropathy |journal=Am. J. Nephrol. |volume=6 |issue=6 |pages=476–81 |date=1986 |pmid=3565506 |doi=10.1159/000167258 |url=}}</ref><ref name="pmid8558697">{{cite journal |vauthors=Chandar J, Abitbol C, Zilleruelo G, Gosalbez R, Montané B, Strauss J |title=Renal tubular abnormalities in infants with hydronephrosis |journal=J. Urol. |volume=155 |issue=2 |pages=660–3 |date=February 1996 |pmid=8558697 |doi= |url=}}</ref><ref name="pmid18295269">{{cite journal |vauthors=Lee JH, Choi HS, Kim JK, Won HS, Kim KS, Moon DH, Cho KS, Park YS |title=Nonrefluxing neonatal hydronephrosis and the risk of urinary tract infection |journal=J. Urol. |volume=179 |issue=4 |pages=1524–8 |date=April 2008 |pmid=18295269 |doi=10.1016/j.juro.2007.11.090 |url=}}</ref><ref name="pmid4610948">{{cite journal |vauthors=King LR, Kazmi SO, Belman AB |title=Natural history of vesicoureteral reflux. Outcome of a trial of nonoperative therapy |journal=Urol. Clin. North Am. |volume=1 |issue=3 |pages=441–55 |date=October 1974 |pmid=4610948 |doi= |url=}}</ref><ref name="pmid20407913">{{cite journal |vauthors=Mesrobian HG |title=Urinary proteome analysis and the management of ureteropelvic junction obstruction |journal=Pediatr. Nephrol. |volume=25 |issue=9 |pages=1595–6 |date=September 2010 |pmid=20407913 |doi=10.1007/s00467-010-1521-2 |url=}}</ref> | ||
** Infection secondary to obstruction | ** Infection secondary to obstruction | ||
** Electrolyte imbalance | ** Electrolyte imbalance | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
Common complications of hydronephrosis include infections, hyperkalemia, metabolic acidosis, and distal renal tubular acidosis, hypertension and renal failure.
Prognosis is generally excellent, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of hydronephrosis include:[1][2][3][4][5]
- Infection secondary to obstruction
- Electrolyte imbalance
- Hyperkalemia
- Metabolic acidosis
- Distal renal tubular acidosis
- Excessive freewater diuresis
- Hypertension
- Real insufficiency and renal failure
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ Kozeny GA, Hurley RM, Vertuno LL, Bansal VK, Zeller WP, Hano JE (1986). "Hypertension, mineralocorticoid-resistant hyperkalemia, and hyperchloremic acidosis in an infant with obstructive uropathy". Am. J. Nephrol. 6 (6): 476–81. doi:10.1159/000167258. PMID 3565506.
- ↑ Chandar J, Abitbol C, Zilleruelo G, Gosalbez R, Montané B, Strauss J (February 1996). "Renal tubular abnormalities in infants with hydronephrosis". J. Urol. 155 (2): 660–3. PMID 8558697.
- ↑ Lee JH, Choi HS, Kim JK, Won HS, Kim KS, Moon DH, Cho KS, Park YS (April 2008). "Nonrefluxing neonatal hydronephrosis and the risk of urinary tract infection". J. Urol. 179 (4): 1524–8. doi:10.1016/j.juro.2007.11.090. PMID 18295269.
- ↑ King LR, Kazmi SO, Belman AB (October 1974). "Natural history of vesicoureteral reflux. Outcome of a trial of nonoperative therapy". Urol. Clin. North Am. 1 (3): 441–55. PMID 4610948.
- ↑ Mesrobian HG (September 2010). "Urinary proteome analysis and the management of ureteropelvic junction obstruction". Pediatr. Nephrol. 25 (9): 1595–6. doi:10.1007/s00467-010-1521-2. PMID 20407913.