Hemolytic-uremic syndrome classification: Difference between revisions
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** Factor I Defeciency (Acquired antibody mediated) | ** Factor I Defeciency (Acquired antibody mediated) | ||
** Membrane co-factor protein Defeciency | ** Membrane co-factor protein Defeciency | ||
** Factor B Overactivity (Complement Factor B mutation) | ** Factor B Overactivity (Complement Factor B mutation)<ref name="pmid24652797">{{cite journal| author=Marinozzi MC, Vergoz L, Rybkine T, Ngo S, Bettoni S, Pashov A et al.| title=Complement factor B mutations in atypical hemolytic uremic syndrome-disease-relevant or benign? | journal=J Am Soc Nephrol | year= 2014 | volume= 25 | issue= 9 | pages= 2053-65 | pmid=24652797 | doi=10.1681/ASN.2013070796 | pmc=4147975 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24652797 }} </ref> | ||
==References== | ==References== |
Revision as of 18:13, 2 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
HUS may be classified according etiology into 4 subtypes including diarrhoea-associated HUS, non-diarrhea-associated HUS (D−HUS), Streptococcus pneumoniae‐associated HUS, diacylglycerol kinase‐ε (DGKE)‐associated HUS.
Classification
Hemolytic-Uremic syndrome (HUS) may be classified as follows:
Typical Or Diarrhea Related
- Shiga-Toxin producing E.Coli/ Shigella infection
Atypical or Non Diarrheal
Primary Causes
- Complement Factor abnormalities
- Factor H Defeciency (Autosomal Dominant)
- Factor I Defeciency (Acquired antibody mediated)
- Membrane co-factor protein Defeciency
- Factor B Overactivity (Complement Factor B mutation)[1]
References
- ↑ Marinozzi MC, Vergoz L, Rybkine T, Ngo S, Bettoni S, Pashov A; et al. (2014). "Complement factor B mutations in atypical hemolytic uremic syndrome-disease-relevant or benign?". J Am Soc Nephrol. 25 (9): 2053–65. doi:10.1681/ASN.2013070796. PMC 4147975. PMID 24652797.