Hemolytic-uremic syndrome overview: Difference between revisions
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==Classification== | ==Classification== | ||
HUS may be classified as Typical (Caused by Shiga-toxin producing E.coli/ Shigella Infection) or Atypical (caused by Complement factor abnormalities, Other viral or bacterial infections, HIV, Malignancy, Organ transplantation, and rarely SLE and pregnancy related). | |||
==Pathophysiology== | ==Pathophysiology== | ||
Revision as of 18:51, 2 August 2018
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Hemolytic-uremic syndrome Microchapters |
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Differentiating Hemolytic-uremic syndrome from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Hemolytic-uremic syndrome overview On the Web |
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American Roentgen Ray Society Images of Hemolytic-uremic syndrome overview |
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Risk calculators and risk factors for Hemolytic-uremic syndrome overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
In medicine, hemolytic-uremic syndrome (or haemolytic-uraemic syndrome, abbreviated HUS) is a disease characterized by microangiopathic hemolytic anemia, acute renal failure and a low platelet count (thrombocytopenia). It is due to the abnormal blood clotting with in the capillaries leading to RBC shearing and destruction while passing through clogged capillaries and obstruction of kidney filtration system by damaged RBC's lead to acute kidney injury and is one of the leading causes of Acute Renal failure in children. The two main types are Typical and atypical Hemolytic uremic syndrome(HUS). Typical HUS is caused following a diarrheal infection by E.Coli OH157:H7 and is responsible for 90 percent of HUS cases in Children. Atypical HUS is not associated with gastrointestinal symptoms and also has a less favorable outcome.
Historical Perspective
Classification
HUS may be classified as Typical (Caused by Shiga-toxin producing E.coli/ Shigella Infection) or Atypical (caused by Complement factor abnormalities, Other viral or bacterial infections, HIV, Malignancy, Organ transplantation, and rarely SLE and pregnancy related).