Thrombocytopenia differential diagnosis: Difference between revisions
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* [[Weight loss]] | * [[Weight loss]] | ||
* [[Embolism|Embolic symptoms]] | * [[Embolism|Embolic symptoms]] | ||
| | |'''Skin''' | ||
* [[Petechiae]] | * [[Petechiae]] | ||
* [[Splinter hemorrhages]] | * [[Splinter hemorrhages]] | ||
* [[Osler's nodes]] | * [[Osler's nodes]] | ||
* [[Janeway lesion|Janeway lesions]] | * [[Janeway lesion|Janeway lesions]] | ||
Oral Cavity | |||
* [[Periodontal diseases|Periodontal]] abnormalities | * [[Periodontal diseases|Periodontal]] abnormalities | ||
'''Eyes''' | |||
* [[Conjunctival hemorrhage]] | * [[Conjunctival hemorrhage]] | ||
* [[Roth's spot|Roth's spots]] in the [[retina]] | * [[Roth's spot|Roth's spots]] in the [[retina]] | ||
'''Ear Nose and Throat''' | |||
* Bobbing of the [[uvula]] may be present among patients with new onset [[aortic regurgitation]]. | * Bobbing of the [[uvula]] may be present among patients with new onset [[aortic regurgitation]]. | ||
'''Cardiovascular''' | |||
* Heart [[Murmur|murmurs]] | * Heart [[Murmur|murmurs]] | ||
* Wide [[pulse pressure]] | * Wide [[pulse pressure]] | ||
'''Lungs''' | |||
* [[Rales]] as a result of [[heart failure]] | * [[Rales]] as a result of [[heart failure]] | ||
'''Abdomen''' | |||
* [[Abdominal pain]] and [[reduced bowel sounds]] due to mesenteric embolization or [[ileus]] | * [[Abdominal pain]] and [[reduced bowel sounds]] due to mesenteric embolization or [[ileus]] | ||
* [[Splenomegaly]] | * [[Splenomegaly]] | ||
* [[Flank pain]] as a result of an [[embolus to the kidney]]. | * [[Flank pain]] as a result of an [[embolus to the kidney]]. | ||
'''Neurologic''' | |||
* [[Septic emboli]] may result in [[stroke]] and focal neurologic findings | * [[Septic emboli]] may result in [[stroke]] and focal neurologic findings | ||
* [[Seizures]] | * [[Seizures]] | ||
Revision as of 10:47, 8 August 2018
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Thrombocytopenia Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Thrombocytopenia differential diagnosis On the Web |
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American Roentgen Ray Society Images of Thrombocytopenia differential diagnosis |
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Risk calculators and risk factors for Thrombocytopenia differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Farbod Zahedi Tajrishi, M.D.
Overview
Thrombocytopenia has a broad range of potential causes. While a good history and physical examination can be helpful to diagnose some of these causes such as drug-induced thrombocytopenia, they usually don't suffice and further evaluation is often needed. There are also some useful points that may guide the physician to an appropriate diagnosis. For example, asymptomatic, isolated thrombocytopenia most probably suggests ITP, while thrombocytopenia in critically ill, hospitalized patients is usually suggestive of iatrogenic causes (eg. dilution), platelet consumption, bone marrow suppression from infection/sepsis, or even drug-induced thrombocytopenia. One should consider however, that a wide variety of other conditions such as autoimmune disorders, nutrient deficiencies, thrombotic microangiopathies could all as well cause thrombocytopenia.
Differential Diagnosis
References
- ↑ Infective endocarditis. Wikipedia (2015). https://en.wikipedia.org/wiki/Infective_endocarditis Accessed on September 24, 2015
- ↑ Cohen AT, Dobromirski M, Gurwith MM (2014). "Managing pulmonary embolism from presentation to extended treatment". Thromb Res. 133 (2): 139–48. doi:10.1016/j.thromres.2013.09.040. PMID 24182642.