Macrocytic anemia historical perspective: Difference between revisions
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===Discovery=== | ===Discovery=== | ||
Following facts were found in historical perspective:<ref name="pmid11122079">{{cite journal |vauthors=Chanarin I |title=Historical review: a history of pernicious anaemia |journal=Br. J. Haematol. |volume=111 |issue=2 |pages=407–15 |date=November 2000 |pmid=11122079 |doi= |url=}}</ref> | |||
*Megaloblastic anemia and pernicious anemia was first discovered by Osler and Gardner in 1877 at Montreal. | *Megaloblastic anemia and pernicious anemia was first discovered by Osler and Gardner in 1877 at Montreal. | ||
*Increase in bone marrow cellls was noted by Cohnheim in 1876. | *Increase in bone marrow cellls was noted by Cohnheim in 1876. | ||
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==Landmark Events in the Development of Treatment Strategies== | ==Landmark Events in the Development of Treatment Strategies== | ||
In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name]. | In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name]. | ||
==References== | ==References== |
Revision as of 20:35, 20 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Historical Perspective
Discovery
Following facts were found in historical perspective:[1]
- Megaloblastic anemia and pernicious anemia was first discovered by Osler and Gardner in 1877 at Montreal.
- Increase in bone marrow cellls was noted by Cohnheim in 1876.
- The association between megaloblastic(pernicious) anemia and spinal cord lesions was made in 1887 by Lichtheim.
- Subacute combined degeneration of spinal cord was coined by Russell et al in 1900.
- In 1908, Cabot was the first to discover the association between megaloblastic anemia and the development of numbness and tingling of extremities.
- In 1923, Minot and Murphy started a diet for people with anemia which had animal sources like liver, muscle meat, leafy vegetables, eggs and milk. they discovered rises in cell count and hemoglobin levels.
- In 1934, Whipple, Minot and Murphy were awarded with Nobel prize for medicine and physiology for saving the lives of anemic people with dietary measures.
Outbreaks
There have been several outbreaks of [disease name], which are summarized below:
Landmark Events in the Development of Treatment Strategies
In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].