Acute lymphoblastic leukemia history and symptoms: Difference between revisions
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==Symptoms== | ==Symptoms== | ||
Common symptoms of acute lymphoblastic leukemia include the following:<ref name="pmid27647842">{{cite journal |vauthors=Clarke RT, Van den Bruel A, Bankhead C, Mitchell CD, Phillips B, Thompson MJ |title=Clinical presentation of childhood leukaemia: a systematic review and meta-analysis |journal=Arch. Dis. Child. |volume=101 |issue=10 |pages=894–901 |date=October 2016 |pmid=27647842 |doi=10.1136/archdischild-2016-311251 |url=}}</ref><ref name="pmid4059858">{{cite journal |vauthors=Vesterby A, Myhre Jensen O |title=Aseptic bone/bone marrow necrosis in leukaemia |journal=Scand J Haematol |volume=35 |issue=3 |pages=354–7 |date=September 1985 |pmid=4059858 |doi= |url=}}</ref><ref name="pmid18157042">{{cite journal |vauthors=Sinigaglia R, Gigante C, Bisinella G, Varotto S, Zanesco L, Turra S |title=Musculoskeletal manifestations in pediatric acute leukemia |journal=J Pediatr Orthop |volume=28 |issue=1 |pages=20–8 |date=2008 |pmid=18157042 |doi=10.1097/BPO.0b13e31815ff350 |url=}}</ref><ref name="pmid19100362">{{cite journal |vauthors=Pui CH |title=Acute lymphoblastic leukemia: introduction |journal=Semin. Hematol. |volume=46 |issue=1 |pages=1–2 |date=January 2009 |pmid=19100362 |pmc=2638983 |doi=10.1053/j.seminhematol.2008.09.011 |url=}}</ref> | Common symptoms of acute lymphoblastic leukemia include the following:<ref name="pmid27647842">{{cite journal |vauthors=Clarke RT, Van den Bruel A, Bankhead C, Mitchell CD, Phillips B, Thompson MJ |title=Clinical presentation of childhood leukaemia: a systematic review and meta-analysis |journal=Arch. Dis. Child. |volume=101 |issue=10 |pages=894–901 |date=October 2016 |pmid=27647842 |doi=10.1136/archdischild-2016-311251 |url=}}</ref><ref name="pmid4059858">{{cite journal |vauthors=Vesterby A, Myhre Jensen O |title=Aseptic bone/bone marrow necrosis in leukaemia |journal=Scand J Haematol |volume=35 |issue=3 |pages=354–7 |date=September 1985 |pmid=4059858 |doi= |url=}}</ref><ref name="pmid18157042">{{cite journal |vauthors=Sinigaglia R, Gigante C, Bisinella G, Varotto S, Zanesco L, Turra S |title=Musculoskeletal manifestations in pediatric acute leukemia |journal=J Pediatr Orthop |volume=28 |issue=1 |pages=20–8 |date=2008 |pmid=18157042 |doi=10.1097/BPO.0b13e31815ff350 |url=}}</ref><ref name="pmid19100362">{{cite journal |vauthors=Pui CH |title=Acute lymphoblastic leukemia: introduction |journal=Semin. Hematol. |volume=46 |issue=1 |pages=1–2 |date=January 2009 |pmid=19100362 |pmc=2638983 |doi=10.1053/j.seminhematol.2008.09.011 |url=}}</ref><ref name="pmid28665419">{{cite journal |vauthors=Terwilliger T, Abdul-Hay M |title=Acute lymphoblastic leukemia: a comprehensive review and 2017 update |journal=Blood Cancer J |volume=7 |issue=6 |pages=e577 |date=June 2017 |pmid=28665419 |pmc=5520400 |doi=10.1038/bcj.2017.53 |url=}}</ref> | ||
* Generalised weakness and [[Fatigue (physical)|fatigue]] | * Generalised weakness and [[Fatigue (physical)|fatigue]] | ||
| Line 21: | Line 21: | ||
*[[Arthralgia]] (caused by the spread of "blast" cells to the surface of the bone or into the joint from the marrow cavity) | *[[Arthralgia]] (caused by the spread of "blast" cells to the surface of the bone or into the joint from the marrow cavity) | ||
* [[Dyspnea]] | * [[Dyspnea]] | ||
==References== | ==References== | ||
Revision as of 18:26, 6 September 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Carlos A Lopez, M.D. [3]
Overview
Symptoms of acute lymphoblastic leukemia include generalised weakness and fatigue, frequent or unexplained fever and infections, weight loss and/or loss of appetite, excessive bruising, bleeding from wounds, nosebleeds, petechiae, bone pain, joint pains and dyspnea.
Symptoms
Common symptoms of acute lymphoblastic leukemia include the following:[1][2][3][4][5]
- Generalised weakness and fatigue
- Anemia
- Frequent or unexplained fever and infections
- Weight loss
- Anorexia
- Excessive bruising
- Petechiae
- Excessive bleeding from minor wounds
- Epistaxis
- Bone pain
- Arthralgia (caused by the spread of "blast" cells to the surface of the bone or into the joint from the marrow cavity)
- Dyspnea
References
- ↑ Clarke RT, Van den Bruel A, Bankhead C, Mitchell CD, Phillips B, Thompson MJ (October 2016). "Clinical presentation of childhood leukaemia: a systematic review and meta-analysis". Arch. Dis. Child. 101 (10): 894–901. doi:10.1136/archdischild-2016-311251. PMID 27647842.
- ↑ Vesterby A, Myhre Jensen O (September 1985). "Aseptic bone/bone marrow necrosis in leukaemia". Scand J Haematol. 35 (3): 354–7. PMID 4059858.
- ↑ Sinigaglia R, Gigante C, Bisinella G, Varotto S, Zanesco L, Turra S (2008). "Musculoskeletal manifestations in pediatric acute leukemia". J Pediatr Orthop. 28 (1): 20–8. doi:10.1097/BPO.0b13e31815ff350. PMID 18157042.
- ↑ Pui CH (January 2009). "Acute lymphoblastic leukemia: introduction". Semin. Hematol. 46 (1): 1–2. doi:10.1053/j.seminhematol.2008.09.011. PMC 2638983. PMID 19100362.
- ↑ Terwilliger T, Abdul-Hay M (June 2017). "Acute lymphoblastic leukemia: a comprehensive review and 2017 update". Blood Cancer J. 7 (6): e577. doi:10.1038/bcj.2017.53. PMC 5520400. PMID 28665419.