Thrombotic thrombocytopenic purpura classification: Difference between revisions
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==Classification== | ==Classification== | ||
TTP may be classified into several subtypes based on | TTP may be classified into several subtypes based on ''ADAMTS13'' gene mutations and autoantibody against ADAMTS13: | ||
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'''Hereditary:''' | |||
* Congenital TTP | * Congenital TTP | ||
* Inherited TTP | * Inherited TTP | ||
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}}</ref>. | }}</ref>. | ||
* '''Acquired | * '''Acquired:''' | ||
* Existence of an inhibitory antibody against ADAMS13 due to the variety of conditions. | * Existence of an inhibitory antibody against ADAMS13 due to the variety of conditions. | ||
Revision as of 19:17, 12 September 2018
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Thrombotic thrombocytopenic purpura Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
Classification
TTP may be classified into several subtypes based on ADAMTS13 gene mutations and autoantibody against ADAMTS13:
Hereditary:
- Congenital TTP
- Inherited TTP
- familial TTP
- Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34 [1].
- Acquired:
- Existence of an inhibitory antibody against ADAMS13 due to the variety of conditions.
References
- ↑ Yoshihiro Fujimura, Masanori Matsumoto, Hideo Yagi, Akira Yoshioka, Taei Matsui & Koiti Titani (2002). "Von Willebrand factor-cleaving protease and Upshaw-Schulman syndrome". International journal of hematology. 75 (1): 25–34. PMID 11843286. Unknown parameter
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