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editnews, nocaptcha, Administrators, Widget editors
7,502 edits
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== Splenomegaly differential: ==
== Splenomegaly differential: ==
{| class="wikitable"
{| class="wikitable"
|+
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Category
! rowspan="4" |Category
! colspan="2" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Disease
! colspan="2" rowspan="4" |Disease
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
! rowspan="4" |Etiology
! colspan="12" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Clinical manifestations
! colspan="12" |'''Clinical manifestations'''
! colspan="10" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para−clinical findings
! colspan="10" |'''Para−clinical findings'''
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
! rowspan="4" |'''Gold standard'''
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
! rowspan="4" |Associated findings
|-
|-
! rowspan="3" |'''Demography'''
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
! rowspan="3" |History
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! colspan="5" |'''Symptoms'''
! colspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms
! colspan="5" |Signs
! colspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Signs
! colspan="9" |Lab Findings
! colspan="9" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
! rowspan="3" |Imaging
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
|-
|-
! rowspan="2" |Fever
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
! rowspan="2" |Fatigue
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fatigue
! rowspan="2" |Weight loss
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Weight loss
! rowspan="2" |SOB
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |SOB
! rowspan="2" |Bleeding
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bleeding
! rowspan="2" |BP
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
! rowspan="2" |JVP
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |JVP
! rowspan="2" |Jaundice
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Jaundice
! rowspan="2" |Ascites
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Ascites
! rowspan="2" |Other
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other
! colspan="3" |CBC
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |CBC
! rowspan="2" |PS
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |PS
! rowspan="2" |Iron
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Iron
! rowspan="2" |LFT
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
! rowspan="2" |PT/PTT
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |PT/PTT
! rowspan="2" |BUN/Cr
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
! rowspan="2" |UA
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |UA
|-
|-
!WBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
!Hb
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hb
!Plt
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
|-
|-
| rowspan="3" |'''Congestive'''
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congestive
| colspan="2" |Cirrhosis
| colspan="2" |Cirrhosis
|
|
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|
|
|-
|-
| rowspan="8" |'''Malignancy'''
! rowspan="8" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Malignancy
| colspan="2" |Lymphoma
| colspan="2" |Lymphoma
|
|
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|
|
|-
|-
| colspan="2" |Polycythemia vera
| colspan="2" |Polycythemia Vera
|
|
|
|
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|
|
|-
|-
| rowspan="6" |'''Infection'''
! rowspan="6" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Infection
|Viral
|Viral
|Hepatitis, infectious mononucleosis, cytomegalovirus
|Hepatitis, infectious mononucleosis, cytomegalovirus
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|
|
|-
|-
| rowspan="4" |Inflammation
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Inflammation
| colspan="2" |Sarcoid
| colspan="2" |Sarcoid
|
|
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|
|
|-
|-
| rowspan="6" |Infiltrative
! rowspan="6" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Infiltrative
| colspan="2" |Gaucher disease
| colspan="2" |Gaucher disease
|
|
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|
|
|-
|-
| rowspan="3" |Hematologic (hypersplenic) states
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hematologic (hypersplenic) states
| colspan="2" |Hemolytic anemia
| colspan="2" |Hemolytic anemia
|
|
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|
|
|-
|-
|Category
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Category
| colspan="2" |Disease
! colspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Disease
|Etiology
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
|'''Demography'''
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
|History
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
|Fever
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
|Fatigue
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fatigue
|Weight loss
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Weight loss
|SOB
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |SOB
|Bleeding
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bleeding
|BP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
|JVP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |JVP
|Jaundice
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Jaundice
|Ascites
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Ascites
|Other
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other
|WBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
|Hb
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hb
|Plt
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
|PS
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |PS
|Iron
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Iron
|LFT
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
|PT/PTT
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |PT/PTT
|BUN/Cr
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
|UA
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |UA
|Imaging
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
|'''Gold standard'''
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
|Associated findings
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|}
|}

Revision as of 21:55, 25 September 2018

Splenomegaly differential:

Category Disease Etiology Clinical manifestations Para−clinical findings Gold standard Associated findings
Demography History Symptoms Signs Lab Findings Imaging
Fever Fatigue Weight loss SOB Bleeding BP JVP Jaundice Ascites Other CBC PS Iron LFT PT/PTT BUN/Cr UA
WBC Hb Plt
Congestive Cirrhosis
Heart failure
Thrombosis of portal, hepatic, or splenic veins
Malignancy Lymphoma
Leukemias
Polycythemia Vera
Multiple myeloma
Essential thrombocythemia
Primary myelofibrosis
Primary splenic tumors
Metastatic solid tumors
Infection Viral Hepatitis, infectious mononucleosis, cytomegalovirus
Bacterial Salmonella, Brucella, tuberculosis
Parasitic Malaria, schistosomiasis, toxoplasmosis
Kala-azar (visceral leishmaniasis)
Infective endocarditis
Fungal
Inflammation Sarcoid
Serum sickness
Systemic lupus erythematosus
Felty syndrome
Infiltrative Gaucher disease
Niemann-Pick disease
Amyloidosis
Langerhans cell histiocytosis
Hemophagocytic lymphohistiocytosis
Rosai-Dorfman disease
Hematologic (hypersplenic) states Hemolytic anemia
Sickle cell disease
Granulocyte colony-stimulating factor
Category Disease Etiology Demography History Fever Fatigue Weight loss SOB Bleeding BP JVP Jaundice Ascites Other WBC Hb Plt PS Iron LFT PT/PTT BUN/Cr UA Imaging Gold standard Associated findings
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