Thrombotic thrombocytopenic purpura epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
The most proportion of [[Hemolytic-uremic syndrome|TTP]] cases occurred after 40 years. Congenital forms occur in children. | |||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
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===Race=== | ===Race=== | ||
*TTP usually affects individuals of | *TTP usually affects individuals of theblack race. | ||
===Gender=== | ===Gender=== | ||
*Females are more commonly affected by TTP than men. The females to men ratio is approximately 2 to 1.<ref name="pmid23729372">{{cite journal |vauthors=Reese JA, Muthurajah DS, Kremer Hovinga JA, Vesely SK, Terrell DR, George JN |title=Children and adults with thrombotic thrombocytopenic purpura associated with severe, acquired Adamts13 deficiency: comparison of incidence, demographic and clinical features |journal=Pediatr Blood Cancer |volume=60 |issue=10 |pages=1676–82 |date=October 2013 |pmid=23729372 |doi=10.1002/pbc.24612 |url=}}</ref> | *Females are more commonly affected by TTP than men. The females to men ratio is approximately 2 to 1.<ref name="pmid23729372">{{cite journal |vauthors=Reese JA, Muthurajah DS, Kremer Hovinga JA, Vesely SK, Terrell DR, George JN |title=Children and adults with thrombotic thrombocytopenic purpura associated with severe, acquired Adamts13 deficiency: comparison of incidence, demographic and clinical features |journal=Pediatr Blood Cancer |volume=60 |issue=10 |pages=1676–82 |date=October 2013 |pmid=23729372 |doi=10.1002/pbc.24612 |url=}}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
The most proportion of TTP cases occurred after 40 years. Congenital forms occur in children.
Epidemiology and Demographics
Incidence
- The incidence of acuired TTP is about 0.3 per 100,000 adult per year.[1]
- Data suggests the increased risk of TTP in black race and femal sex.[2]
Prevalence
- The incidence of TTP is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may developTTP.
- The incidence of TTP increases with age; the median age at diagnosis is 40 years. TTP often occurs after 40 years.
Race
- TTP usually affects individuals of theblack race.
Gender
- Females are more commonly affected by TTP than men. The females to men ratio is approximately 2 to 1.[3]
Region
- The majority of TTP cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
References
- ↑ Reese JA, Muthurajah DS, Kremer Hovinga JA, Vesely SK, Terrell DR, George JN (October 2013). "Children and adults with thrombotic thrombocytopenic purpura associated with severe, acquired Adamts13 deficiency: comparison of incidence, demographic and clinical features". Pediatr Blood Cancer. 60 (10): 1676–82. doi:10.1002/pbc.24612. PMID 23729372.
- ↑ Terrell DR, Vesely SK, Kremer Hovinga JA, Lämmle B, George JN (November 2010). "Different disparities of gender and race among the thrombotic thrombocytopenic purpura and hemolytic-uremic syndromes". Am. J. Hematol. 85 (11): 844–7. doi:10.1002/ajh.21833. PMC 3420337. PMID 20799358.
- ↑ Reese JA, Muthurajah DS, Kremer Hovinga JA, Vesely SK, Terrell DR, George JN (October 2013). "Children and adults with thrombotic thrombocytopenic purpura associated with severe, acquired Adamts13 deficiency: comparison of incidence, demographic and clinical features". Pediatr Blood Cancer. 60 (10): 1676–82. doi:10.1002/pbc.24612. PMID 23729372.
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