Palmar plantar erythrodysesthesia

Palmar plantar erythrodysesthesia Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Zain Fatiwala M.D.

Synonyms Other names for PPE include palmar-plantar erythrodysesthesia; palmoplantar erythrodysesthesia, palmoplantar erythema, hand-foot syndrome, peculiar AE, chemotherapy-induced AE, acral erythema (AE), toxic erythema of the palms and soles, palmar-plantar erythema, and Burgdorf’s reaction.

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | CT | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

References

• Apisarnthanarax, N and Duvic MM. Dermatologic Complications of Cancer Chemotherapy in Holland-Frei Cancer Medicine - 6th Ed., Ch. 147, Kufe, DW et al editors, BC Decker Inc, Hamilton, Ontario. 2003.
• Baack B, Burgdorf W (1991). "Chemotherapy-induced acral erythema". J Am Acad Dermatol. 24 (3): 457–61. PMID 2061446.
• Crider M, Jansen J, Norins A, McHale M (1986). "Chemotherapy-induced acral erythema in patients receiving bone marrow transplantation". Arch Dermatol. 122 (9): 1023–7. PMID 3527075.CS1 maint: Multiple names: authors list (link)
• Demirçay Z, Gürbüz O, Alpdoğan T, Yücelten D, Alpdoğan O, Kurtkaya O, Bayik M (1997). "Chemotherapy-induced acral erythema in leukemic patients: a report of 15 cases". Int J Dermatol. 36 (8): 593–8. PMID 9329890.CS1 maint: Multiple names: authors list (link)
• Vukelja S, Baker W, Burris H, Keeling J, Von Hoff D (1993). "Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with taxotere". J Natl Cancer Inst. 85 (17): 1432–3. PMID 8102408.CS1 maint: Multiple names: authors list (link)
• Zimmerman G, Keeling J, Burris H, Cook G, Irvin R, Kuhn J, McCollough M, Von Hoff D (1995). "Acute cutaneous reactions to docetaxel, a new chemotherapeutic agent". Arch Dermatol. 131 (2): 202–6. PMID 7857119.CS1 maint: Multiple names: authors list (link)
• Zuehlke R (1974). "Erythematous eruption of the palms and soles associated with mitotane therapy". Dermatologica. 148 (2): 90–2. PMID 4276191.