Vascular anomalies: Difference between revisions
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{{Family tree | | | | | | | | | | | | | A01 | {{Family tree | | | | | | | | | | | | | A01 | | | | | | | | | | |A01= Vascular malformations}} | ||
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{{Family tree | | | B01 | | | | B02 | | | | | B03 | | | | B04 | {{Family tree | | | B01 | | | | B02 | | | | | B03 | | | | B04 | |B01=Simple vascular malformations|B02=Combined vascular malformations|B03=Vascular malformations of major named vessels|B04=Vascular malformations asscoiated with other anomalies}} | ||
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{{Family tree | | | |!| | | | | I02 | | | | | I03 | | | | I04 | {{Family tree | | | |!| | | | | I02 | | | | | I03 | | | | I04 | |I02=Combined vascular malformations*<table class="wikitable"> | ||
<table class="wikitable"> | |||
<tr><td>'''CM + VM'''</td><td>Capillary-venous malformation</td><td>CVM</td></tr> | <tr><td>'''CM + VM'''</td><td>Capillary-venous malformation</td><td>CVM</td></tr> | ||
<tr><td>'''CM + LM'''</td><td>Capillary-lymphatic malformation</td><td>CLM</td></tr> | <tr><td>'''CM + LM'''</td><td>Capillary-lymphatic malformation</td><td>CLM</td></tr> | ||
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<tr><td>'''CM + VM + AVM'''</td><td>Capillary-venous-arteriovenous malformation</td><td>CVAVM</td></tr> | <tr><td>'''CM + VM + AVM'''</td><td>Capillary-venous-arteriovenous malformation</td><td>CVAVM</td></tr> | ||
<tr><td>'''CM + LM + VM + AVM'''</td><td>Capillary-lymphatic-venous-arteriovenous malformation</td><td>CLVAVM</td></tr> | <tr><td>'''CM + LM + VM + AVM'''</td><td>Capillary-lymphatic-venous-arteriovenous malformation</td><td>CLVAVM</td></tr> | ||
</table> | </table>|I03='''Anomalies of major named vessels'''<br>(also known as "channel type" or "truncal" vascular malformations)<br><table> | ||
|I03='''Anomalies of major named vessels'''<br>(also known as "channel type" or "truncal" vascular malformations)<br> | |||
<table> | |||
<tr><td>Affect</td></tr> | <tr><td>Affect</td></tr> | ||
<tr><td>• Lymphatics<td></tr> | <tr><td>• Lymphatics<td></tr> | ||
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<tr><td>• Communication (AVF)<td></tr> | <tr><td>• Communication (AVF)<td></tr> | ||
<tr><td>• Persistence (of<br>embryonal vessel)<td></tr> | <tr><td>• Persistence (of<br>embryonal vessel)<td></tr> | ||
</table> | </table>|I04=Vascular malformations associated with other anomalies<table class="wikitable"> | ||
|I04=Vascular malformations associated with other anomalies | |||
<table class="wikitable"> | |||
<tr><td>'''Klippel-Trenaunay syndrome'''</td><td>CM + VM +/-LM + limb overgrowth</td></tr> | <tr><td>'''Klippel-Trenaunay syndrome'''</td><td>CM + VM +/-LM + limb overgrowth</td></tr> | ||
<tr><td>'''Parke's Weber syndrome'''</td><td>CM + AVF + limb overgrowth</td></tr> | <tr><td>'''Parke's Weber syndrome'''</td><td>CM + AVF + limb overgrowth</td></tr> | ||
<tr><td>'''Servelle-Martorell syndrome'''</td><td>Limb VM + bone undergrowth</td></tr> | <tr><td>'''Servelle-Martorell syndrome'''</td><td>Limb VM + bone undergrowth</td></tr> | ||
<tr><td>'''Sturge-Weber syndrome'''</td><td>Facial + leptomeningeal CM + eye anomalies | <tr><td>'''Sturge-Weber syndrome'''</td><td>Facial + leptomeningeal CM + eye anomalies +/-bone and/or soft tissue overgrowth</td></tr> | ||
+/-bone and/or soft tissue overgrowth</td></tr> | |||
<tr><td>'''Maffucci syndrome'''</td><td>VM +/-spindle-cell hemangioma + enchondroma</td></tr> | <tr><td>'''Maffucci syndrome'''</td><td>VM +/-spindle-cell hemangioma + enchondroma</td></tr> | ||
<tr><td>'''CLOVES syndrome'''</td><td>LM + VM + CM +/-AVM+ lipomatous overgrowth</td></tr> | <tr><td>'''CLOVES syndrome'''</td><td>LM + VM + CM +/-AVM+ lipomatous overgrowth</td></tr> | ||
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<tr><td colspan="2">'''Macrocephaly-CM (M-CM / MCAP)'''</td></tr> | <tr><td colspan="2">'''Macrocephaly-CM (M-CM / MCAP)'''</td></tr> | ||
<tr><td colspan="2">'''Microcephaly-CM (MICCAP)'''</td></tr> | <tr><td colspan="2">'''Microcephaly-CM (MICCAP)'''</td></tr> | ||
</table> | </table>|}} | ||
|}} | |||
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{{Family tree | | | C01 | | | C02 | | | C03 | | | C04 | | | C05 | {{Family tree | | | C01 | | | C02 | | | C03 | | | C04 | | | C05 | |C01=Capillary malformations (CM)|C02=Lymphatic malformations (LM)|C03=Venous malformations (VM)|C04=Arteriovenous malformations (AVM)|C05=Arteriovenous fistula}} | ||
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{{Family tree | | |)| D01 | |)| E01 | |)| F01 | |)| G01 | |)| H01 | {{Family tree | | |)| D01 | |)| E01 | |)| F01 | |)| G01 | |)| H01 | |D01=Nevus simplex / salmon patch, “angel kiss”, “stork bite”|E01=<table> | ||
|E01=<table> | |||
<tr><td>Common (cystic) LM </td></tr> | <tr><td>Common (cystic) LM </td></tr> | ||
<tr><td>• Macrocystic LM<td></tr> | <tr><td>• Macrocystic LM<td></tr> | ||
<tr><td>• Microcystic LM<td></tr> | <tr><td>• Microcystic LM<td></tr> | ||
<tr><td>• Mixed cystic LM<td></tr> | <tr><td>• Mixed cystic LM<td></tr> | ||
</table> | </table>|F01=Common VM|G01=Sporadic|H01=Sporadic}} | ||
|F01=Common VM|G01=Sporadic|H01=Sporadic}} | {{Family tree | | |!| | | | |!| | | | |!| | | | |!| | | | |!| | | | |}} | ||
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{{Family tree | | |)| D02 | |)| E02 | |)| F02 | |)| G02 | |)| H02 | | |||
|D02=<table> | |||
<tr><td>Cutaneous and/or mucosal CM (also known as “port-wine” stain) </td></tr> | <tr><td>Cutaneous and/or mucosal CM (also known as “port-wine” stain) </td></tr> | ||
<tr><td>• Nonsyndromic CM<td></tr> | <tr><td>• Nonsyndromic CM<td></tr> | ||
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<tr><td>• CM with bone and/or soft tissues overgrowth <td></tr> | <tr><td>• CM with bone and/or soft tissues overgrowth <td></tr> | ||
<tr><td>• Diffuse CM with overgrowth (DCMO) <td></tr> | <tr><td>• Diffuse CM with overgrowth (DCMO) <td></tr> | ||
</table> | </table>|E02=Generalized lymphatic anomaly (GLA)<br>Kaposiform lymphangiomatosis (KLA)|F02=Familial VM cutaneo-mucosal (VMCM)|G02=In HHT|H02=In HHT|}} | ||
|E02=Generalized lymphatic anomaly (GLA)<br>Kaposiform lymphangiomatosis (KLA)|F02=Familial VM cutaneo-mucosal (VMCM)|G02=In HHT|H02=In HHT|}} | {{Family tree | | |!| | | | |!| | | | |!| | | | |!| | | | |!| | | | |}} | ||
{{Family tree | | |!| | | | |!| | | | |!| | | | |!| | | | |! | {{Family tree | | |)| D03 | |)| E03 | |)| F03 | |)| G03 | |)| H03 | |D03=<table> | ||
{{Family tree | | |)| D03 | |)| E03 | |)| F03 | |)| G03 | |)| H03 | | |||
|D03=<table> | |||
<tr><td>Reticulate CM </td></tr> | <tr><td>Reticulate CM </td></tr> | ||
<tr><td>• CM of MIC-CAP (microcephaly-capillary malformation)<td></tr> | <tr><td>• CM of MIC-CAP (microcephaly-capillary malformation)<td></tr> | ||
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</table> | </table> | ||
|E03=LM in Gorham-Stout disease|F03=Blue rubber bleb nevus (Bean) syndrome VM|G03=In CM-AVM|H03=In CM-AVM|}} | |E03=LM in Gorham-Stout disease|F03=Blue rubber bleb nevus (Bean) syndrome VM|G03=In CM-AVM|H03=In CM-AVM|}} | ||
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{{Family tree | | |)| D04 | |)| E04 | |)| F04 | |`| G04 | |`| H04 | {{Family tree | | |)| D04 | |)| E04 | |)| F04 | |`| G04 | |`| H04 | | |D04=CM of CM-AVM|E04=Channel type LM|F04=Glomuvenous malformation (GVM)|G04=Others|H04=Others|}} | ||
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{{Family tree | | |)| D05 | |)| E05 | |)| F05 | {{Family tree | | |)| D05 | |)| E05 | |)| F05 | | | | | | | | | | | | |D05=Cutis marmorata telangiectatica congenita (CMTC)|E05=“Acquired” progressive lymphatic anomaly (so called acquired progressive "lymphangioma")|F05=Cerebral cavernous malformation (CCM) |}} | ||
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{{Family tree | | |)| D06 | |)| E06 | |)| F06 | {{Family tree | | |)| D06 | |)| E06 | |)| F06 | | | | | | | | | | | | |D06=Others|E06=Primary lymphedema |F06=Familial intraosseous vascular malformation (VMOS)|}} | ||
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{{Family tree | | |`| D07 | |`| E07 | |)| F07 | | | | | | | | | | | | | {{Family tree | | |`| D07 | |`| E07 | |)| F07 | | | | | | | | | | | | |D07=<table> | ||
|D07=<table> | |||
<tr><td>Telangiectasia </td></tr> | <tr><td>Telangiectasia </td></tr> | ||
<tr><td>• Hereditary hemorrhagic telangiectasia (HHT) <td></tr> | <tr><td>• Hereditary hemorrhagic telangiectasia (HHT) <td></tr> | ||
<tr><td>• Others<td></tr> | <tr><td>• Others<td></tr> | ||
</table> | </table>|E07=Others|F07=Verrucous venous malformation (formerly verrucous hemangioma)|}} | ||
|E07=Others|F07=Verrucous venous malformation (formerly verrucous hemangioma)|}} | {{Family tree | | | | | | | | | | | | |!| | | | | | | | | | | | | | | |}} | ||
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{{Family tree | | | | | | | | | | | | |`| F08 | {{Family tree | | | | | | | | | | | | | | | | | | | | | | | | | | | | |}} | ||
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Revision as of 18:47, 8 October 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hannan Javed, M.D.[2], Anmol Pitliya, M.B.B.S. M.D.[3]
Overview
Classification
Classification of Vascular Tumors
Vascular tumors | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Benign | Locally aggressive or borderline | Malignant | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Infantile hemangioma / Hemangioma of infancy | Kaposiform hemangioendothelioma* | Angiosarcoma | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Congenital hemangioma* | Retiform hemangioendothelioma | Epithelioid hemangioendothelioma | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tufted angioma* | Papillary intralymphatic angioendothelioma (PILA), Dabska tumor | Others | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Spindle-cell hemangioma | Composite hemangioendothelioma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Epithelioid hemangioma | Pseudomyogenic hemangioendothelioma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Pyogenic granuloma (also known as lobular capillary hemangioma) | Polymorphous hemangioendothelioma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Hemangioendothelioma not otherwise specified | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
'
| Kaposi sarcoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Others | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
*congenital hemangioma (rapidly involuting type) and tufted angioma may be associated with thrombocytopenia and/or consumptive coagulopathy in some cases. Many experts consider tufted angioma and kaposiform hemangioendothelioma to be part of a spectrum rather than distinct entities
Classification of Vascular Malformations
Vascular malformations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Simple vascular malformations | Combined vascular malformations | Vascular malformations of major named vessels | Vascular malformations asscoiated with other anomalies | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Combined vascular malformations*
| Anomalies of major named vessels (also known as "channel type" or "truncal" vascular malformations)
| Vascular malformations associated with other anomalies
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Capillary malformations (CM) | Lymphatic malformations (LM) | Venous malformations (VM) | Arteriovenous malformations (AVM) | Arteriovenous fistula | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Nevus simplex / salmon patch, “angel kiss”, “stork bite” |
| Common VM | Sporadic | Sporadic | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Generalized lymphatic anomaly (GLA) Kaposiform lymphangiomatosis (KLA) | Familial VM cutaneo-mucosal (VMCM) | In HHT | In HHT | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| LM in Gorham-Stout disease | Blue rubber bleb nevus (Bean) syndrome VM | In CM-AVM | In CM-AVM | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CM of CM-AVM | Channel type LM | Glomuvenous malformation (GVM) | Others | Others | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cutis marmorata telangiectatica congenita (CMTC) | “Acquired” progressive lymphatic anomaly (so called acquired progressive "lymphangioma") | Cerebral cavernous malformation (CCM) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Others | Primary lymphedema | Familial intraosseous vascular malformation (VMOS) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Others | Verrucous venous malformation (formerly verrucous hemangioma) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Others | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||