Lymphangioma diagnostic study of choice: Difference between revisions
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=== Study of choice: === | === Study of choice: === | ||
* MRI is the gold standard test for the diagnosis of lymphangioma. | * MRI is the gold standard test for the diagnosis of lymphangioma.<ref name="pmid11801972">{{cite journal |vauthors=Kennedy TL, Whitaker M, Pellitteri P, Wood WE |title=Cystic hygroma/lymphangioma: a rational approach to management |journal=Laryngoscope |volume=111 |issue=11 Pt 1 |pages=1929–37 |date=November 2001 |pmid=11801972 |doi=10.1097/00005537-200111000-00011 |url=}}</ref> | ||
* MRI can mar the degree of involvement and extent of lesion. | * MRI can mar the degree of involvement and extent of lesion. | ||
* MRI can prevent extensive, incomplete surgical resection, because poorly removed lesion can lead to recurrence. | * MRI can prevent extensive, incomplete surgical resection, because poorly removed lesion can lead to recurrence. | ||
=== Biopsy: === | === Biopsy: === | ||
Biopsy and | Biopsy is used to analyze the structure of tissue. It shows<ref name="pmid15402902">{{cite journal |vauthors=WARD GE, HENDRICK JW, CHAMBERS RG |title=Cystic hygroma of the neck |journal=West J Surg Obstet Gynecol |volume=58 |issue=2 |pages=41–7, illust |date=February 1950 |pmid=15402902 |doi= |url=}}</ref><ref name="Turki2017">{{cite journal|last1=Turki|first1=Ali|title=Abdominal Cystic Lymphangioma in Adults: Diagnostic Difficulties and Surgical Outcome|journal=Journal of Universal Surgery|volume=04|issue=05|year=2017|issn=22546758|doi=10.21767/2254-6758.100066}}</ref> | ||
*Dilated lymph channels ultimately causes the papillary dermis to expand. | |||
*THese channels extend to subcutis. | |||
*Deeper vessels have larger lumen and muscular coat. | |||
*The lumen has lymphatic fluid, but it often contains red blood cells, lymphocytes, macrophages, and neutrophils. | |||
*These channels re lined by endothelial cells. | |||
*Numerous lymphoid cells are also seen. | |||
=== Histochemical staining: === | === Histochemical staining: === | ||
* Histochemical staining is recommended to document lymphangioma. | * Histochemical staining is recommended to document lymphangioma.<ref name="PaalThompson1998">{{cite journal|last1=Paal|first1=Edina|last2=Thompson|first2=Lester D.|last3=Heffess|first3=Clara S.|title=A clinicopathologic and immunohistochemical study of ten pancreatic lymphangiomas and a review of the literature|journal=Cancer|volume=82|issue=11|year=1998|pages=2150–2158|issn=0008-543X|doi=10.1002/(SICI)1097-0142(19980601)82:11<2150::AID-CNCR9>3.0.CO;2-Z}}</ref> | ||
=== Other Tests: === | === Other Tests: === | ||
In addition to above, various investigations must be performed in the following order: | In addition to above, various investigations must be performed in the following order:<ref name="pmid24691940">{{cite journal |vauthors=Park SH, Moon SK, Sung JY |title=Sonographic findings in a case of scrotal lymphangioma |journal=J Clin Ultrasound |volume=42 |issue=4 |pages=234–6 |date=May 2014 |pmid=24691940 |doi=10.1002/jcu.22095 |url=}}</ref><ref name="PaalThompson1998">{{cite journal|last1=Paal|first1=Edina|last2=Thompson|first2=Lester D.|last3=Heffess|first3=Clara S.|title=A clinicopathologic and immunohistochemical study of ten pancreatic lymphangiomas and a review of the literature|journal=Cancer|volume=82|issue=11|year=1998|pages=2150–2158|issn=0008-543X|doi=10.1002/(SICI)1097-0142(19980601)82:11<2150::AID-CNCR9>3.0.CO;2-Z}}</ref><ref name="pmid12063422">{{cite journal |vauthors=Matter D, Grosshans E, Muller J, Furderer C, Mathelin C, Warter S, Bellocq JP, Maillot C |title=[Sonographic imaging of lymphatic vessels compared to other methods] |language=French |journal=J Radiol |volume=83 |issue=5 |pages=599–609 |date=May 2002 |pmid=12063422 |doi= |url=}}</ref> | ||
* Plain radiograph | * Plain radiograph | ||
* Ultrasound | * Ultrasound | ||
| Line 21: | Line 28: | ||
== References == | == References == | ||
{reflist|2} | |||
<references /> | <references /> | ||
Revision as of 19:52, 13 October 2018
Overview
Diagnostic Study of Choice
Study of choice:
- MRI is the gold standard test for the diagnosis of lymphangioma.[1]
- MRI can mar the degree of involvement and extent of lesion.
- MRI can prevent extensive, incomplete surgical resection, because poorly removed lesion can lead to recurrence.
Biopsy:
Biopsy is used to analyze the structure of tissue. It shows[2][3]
- Dilated lymph channels ultimately causes the papillary dermis to expand.
- THese channels extend to subcutis.
- Deeper vessels have larger lumen and muscular coat.
- The lumen has lymphatic fluid, but it often contains red blood cells, lymphocytes, macrophages, and neutrophils.
- These channels re lined by endothelial cells.
- Numerous lymphoid cells are also seen.
Histochemical staining:
- Histochemical staining is recommended to document lymphangioma.[4]
Other Tests:
In addition to above, various investigations must be performed in the following order:[5][4][6]
- Plain radiograph
- Ultrasound
- CT scan
References
{reflist|2}
- ↑ Kennedy TL, Whitaker M, Pellitteri P, Wood WE (November 2001). "Cystic hygroma/lymphangioma: a rational approach to management". Laryngoscope. 111 (11 Pt 1): 1929–37. doi:10.1097/00005537-200111000-00011. PMID 11801972.
- ↑ WARD GE, HENDRICK JW, CHAMBERS RG (February 1950). "Cystic hygroma of the neck". West J Surg Obstet Gynecol. 58 (2): 41–7, illust. PMID 15402902.
- ↑ Turki, Ali (2017). "Abdominal Cystic Lymphangioma in Adults: Diagnostic Difficulties and Surgical Outcome". Journal of Universal Surgery. 04 (05). doi:10.21767/2254-6758.100066. ISSN 2254-6758.
- ↑ 4.0 4.1 Paal, Edina; Thompson, Lester D.; Heffess, Clara S. (1998). "A clinicopathologic and immunohistochemical study of ten pancreatic lymphangiomas and a review of the literature". Cancer. 82 (11): 2150–2158. doi:10.1002/(SICI)1097-0142(19980601)82:11<2150::AID-CNCR9>3.0.CO;2-Z. ISSN 0008-543X.
- ↑ Park SH, Moon SK, Sung JY (May 2014). "Sonographic findings in a case of scrotal lymphangioma". J Clin Ultrasound. 42 (4): 234–6. doi:10.1002/jcu.22095. PMID 24691940.
- ↑ Matter D, Grosshans E, Muller J, Furderer C, Mathelin C, Warter S, Bellocq JP, Maillot C (May 2002). "[Sonographic imaging of lymphatic vessels compared to other methods]". J Radiol (in French). 83 (5): 599–609. PMID 12063422.