Lymphangioma (patient information): Difference between revisions
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==Diagnosis== | ==Diagnosis== | ||
=== Biopsy: === | |||
* [[Biopsy]] is used to analyze the structure of tissue. | |||
* It shows:<ref name="pmid21938186" /> | |||
**Dilated [[lymph]] channels ultimately causes the [[papillary]] [[dermis]] to expand. | |||
**These channels extend to [[subcutis]]. | |||
**Deeper vessels have larger [[lumen]] and [[muscular]] coat. | |||
**The lumen has lymphatic fluid, but it often contains [[red blood cells]], [[Lymphocyte|lymphocytes]], [[macrophage]]<nowiki/>s, and [[neutrophils]]. | |||
**These channels are lined by [[endothelial cells]]. | |||
**Numerous [[Lymphoid cell|lymphoid cells]] are also seen. | |||
=== Histochemical staining: === | |||
* Histochemical staining is recommended to document [[lymphangioma]].<ref name="SauterFoedinger2016">{{cite journal|last1=Sauter|first1=Birthe|last2=Foedinger|first2=Dagmar|last3=Sterniczky|first3=Barbara|last4=Wolff|first4=Klaus|last5=Rappersberger|first5=Klemens|title=Immunoelectron Microscopic Characterization of Human Dermal Lymphatic Microvascular Endothelial Cells: Differential Expression of CD31, CD34, and Type IV Collagen with Lymphatic Endothelial Cells vs Blood Capillary Endothelial Cells in Normal Human Skin, Lymphangioma, and Hemangioma In Situ|journal=Journal of Histochemistry & Cytochemistry|volume=46|issue=2|year=2016|pages=165–176|issn=0022-1554|doi=10.1177/002215549804600205}}</ref> | |||
=== MRI: === | |||
* MRI is primarily used for the diagnosis of lymphangioma. | |||
* MRI can mar the degree of involvement and extent of lesion. | |||
* MRI can prevent extensive, incomplete surgical resection, because poorly removed lesion can lead to recurrence. | |||
==When to seek urgent medical care?== | ==When to seek urgent medical care?== | ||
Revision as of 14:17, 18 October 2018
For the WikiDoc page on this topic, click here
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Lymphangioma |
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Lymphangioma On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Lymphangioma is abnormality of lymph vessels.
What are the symptoms of Lymphangioma?
- The majority of patients with lymphangioma are asymptomatic.
- As the mass increases in size, lymphangioma patients may develop site-specific symptoms, such as:
- Dysphagia
- Difficulty breathing
- Constipation
- Failure to thrive
What causes Lymphangioma?
- There are no known direct causes for lymphangioma.
- Cystic hygroma usually presents in syndromes such as Turner syndrome and Down syndrome.
- Therefore it is thought that the lymphatic malformations can arise from gene mutations, occuring as missing or deleted part of chromosomes.
- Acquired lymphangioma circumscriptum occur as a sequele of chronic lymphatic obstruction such as after surgery, infections or radiotherapy
Who is at highest risk?
The most potent risk factor in the development of lymphangioma is the presence of genetic disorders such as Turner syndrome, Down syndrome, and Noonan syndrome.[1]
Diagnosis
Biopsy:
- Biopsy is used to analyze the structure of tissue.
- It shows:[1]
- Dilated lymph channels ultimately causes the papillary dermis to expand.
- These channels extend to subcutis.
- Deeper vessels have larger lumen and muscular coat.
- The lumen has lymphatic fluid, but it often contains red blood cells, lymphocytes, macrophages, and neutrophils.
- These channels are lined by endothelial cells.
- Numerous lymphoid cells are also seen.
Histochemical staining:
- Histochemical staining is recommended to document lymphangioma.[2]
MRI:
- MRI is primarily used for the diagnosis of lymphangioma.
- MRI can mar the degree of involvement and extent of lesion.
- MRI can prevent extensive, incomplete surgical resection, because poorly removed lesion can lead to recurrence.
When to seek urgent medical care?
Treatment options
Where to find medical care for Lymphangioma?
Directions to Hospitals Treating Lymphangioma
Prevention of Lymphangioma
What to expect (Outlook/Prognosis)?
Possible complications
Source
- ↑ Invalid
<ref>tag; no text was provided for refs namedpmid21938186 - ↑ Sauter, Birthe; Foedinger, Dagmar; Sterniczky, Barbara; Wolff, Klaus; Rappersberger, Klemens (2016). "Immunoelectron Microscopic Characterization of Human Dermal Lymphatic Microvascular Endothelial Cells: Differential Expression of CD31, CD34, and Type IV Collagen with Lymphatic Endothelial Cells vs Blood Capillary Endothelial Cells in Normal Human Skin, Lymphangioma, and Hemangioma In Situ". Journal of Histochemistry & Cytochemistry. 46 (2): 165–176. doi:10.1177/002215549804600205. ISSN 0022-1554.