Waldenström's macroglobulinemia other diagnostic studies: Difference between revisions
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{{Waldenström's macroglobulinemia}} | {{Waldenström's macroglobulinemia}} | ||
{{CMG}} {{AE}} {{ | {{CMG}} {{AE}} {{RAK}} | ||
==Overview== | ==Overview== | ||
Other diagnostic studies for [disease name] include nerve conduction tests, electromyography, funduscopy, and plasma viscosity. | |||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
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**Dilated, segmented, and tortuous retinal veins giving a "sausage link" appearance | **Dilated, segmented, and tortuous retinal veins giving a "sausage link" appearance | ||
***Useful in patients with suspected hyperviscosity syndrome | ***Useful in patients with suspected hyperviscosity syndrome | ||
* '''Plasma viscosity''', which demonstrates: | * '''Plasma viscosity''', which demonstrates:<ref name="pmid4014299">{{cite journal| author=Crawford J, Cox EB, Cohen HJ| title=Evaluation of hyperviscosity in monoclonal gammopathies. | journal=Am J Med | year= 1985 | volume= 79 | issue= 1 | pages= 13-22 | pmid=4014299 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4014299 }} </ref> | ||
**Values > 1.5 centipoise | **Values > 1.5 centipoise | ||
***Should be measured in patients presenting with signs and symptoms suggestive of hyperviscosity syndrome or whenever the monoclonal IgM protein spike is > 4 g/dL. | ***Should be measured in patients presenting with signs and symptoms suggestive of hyperviscosity syndrome or whenever the monoclonal IgM protein spike is > 4 g/dL. | ||
Revision as of 03:05, 31 October 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Roukoz A. Karam, M.D.[2]
Overview
Other diagnostic studies for [disease name] include nerve conduction tests, electromyography, funduscopy, and plasma viscosity.
Other Diagnostic Studies
Other diagnostic studies for Waldenström macroglobulinemia include:
- Nerve conduction tests and electromyography, which demonstrates:[1]
- demyelination with sensory involvement more than motor
- Funduscopy, which demonstrates:[2]
- Dilated, segmented, and tortuous retinal veins giving a "sausage link" appearance
- Useful in patients with suspected hyperviscosity syndrome
- Dilated, segmented, and tortuous retinal veins giving a "sausage link" appearance
- Plasma viscosity, which demonstrates:[3]
- Values > 1.5 centipoise
- Should be measured in patients presenting with signs and symptoms suggestive of hyperviscosity syndrome or whenever the monoclonal IgM protein spike is > 4 g/dL.
- Values > 1.5 centipoise
References
- ↑ Nobile-Orazio E, Marmiroli P, Baldini L, Spagnol G, Barbieri S, Moggio M, Polli N, Polli E, Scarlato G (1987). "Peripheral neuropathy in macroglobulinemia: incidence and antigen-specificity of M proteins". Neurology. 37 (9): 1506–14. PMID 2442666.
- ↑ Castillo JJ, Garcia-Sanz R, Hatjiharissi E, Kyle RA, Leleu X, McMaster M; et al. (2016). "Recommendations for the diagnosis and initial evaluation of patients with Waldenström Macroglobulinaemia: A Task Force from the 8th International Workshop on Waldenström Macroglobulinaemia". Br J Haematol. 175 (1): 77–86. doi:10.1111/bjh.14196. PMC 5154335. PMID 27378193.
- ↑ Crawford J, Cox EB, Cohen HJ (1985). "Evaluation of hyperviscosity in monoclonal gammopathies". Am J Med. 79 (1): 13–22. PMID 4014299.