Hairy cell leukemia diagnotic study of choice: Difference between revisions

Jump to navigation Jump to search
Line 3: Line 3:
{{CMG}}; {{AE}} {{VKG}}
{{CMG}}; {{AE}} {{VKG}}
== Overview ==
== Overview ==
[[Bone marrow]] (BM) aspirate, [[peripheral blood]] and [[trephine]] biopsies are the gold standard test for the diagnosis of [[hairy cell leukemia]].
[[peripheral blood]] are the gold standard test for the diagnosis of [[hairy cell leukemia]].


== Diagnostic Study of Choice ==
== Diagnostic Study of Choice ==
Line 12: Line 12:
Peripheral blood smears is one of the gold standard test for the diagnosis of [[hairy cell leukemia]].
Peripheral blood smears is one of the gold standard test for the diagnosis of [[hairy cell leukemia]].


The following result of peripheral blood smears is confirmatory of [[hairy cell leukemia]]:<ref name="Cazzola2016">{{cite journal|last1=Cazzola|first1=M.|title=Introduction to a review series: the 2016 revision of the WHO classification of tumors of hematopoietic and lymphoid tissues|journal=Blood|volume=127|issue=20|year=2016|pages=2361–2364|issn=0006-4971|doi=10.1182/blood-2016-03-657379}}</ref>
The following result of peripheral blood smears is confirmatory of [[hairy cell leukemia]]:
* Oval nuclei and abundant cytoplasm with "hairy" projections
* Oval nuclei and abundant cytoplasm with "hairy" projections
* Fried egg appearance
* Fried egg appearance
Line 18: Line 18:
* Mast cells numbers elevation
* Mast cells numbers elevation
* Extravasated red cells are positive in peripheral blood smear of [[hairy cell leukemia]] patients
* Extravasated red cells are positive in peripheral blood smear of [[hairy cell leukemia]] patients
'''Bone marrow'''
 
*
== References ==
.
<references />

Revision as of 17:19, 20 November 2018


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

peripheral blood are the gold standard test for the diagnosis of hairy cell leukemia.

Diagnostic Study of Choice

Study of choice

Peripheral blood smear:

Peripheral blood smears is one of the gold standard test for the diagnosis of hairy cell leukemia.

The following result of peripheral blood smears is confirmatory of hairy cell leukemia:

  • Oval nuclei and abundant cytoplasm with "hairy" projections
  • Fried egg appearance
  • Loose chromatin
  • Mast cells numbers elevation
  • Extravasated red cells are positive in peripheral blood smear of hairy cell leukemia patients

References