Sandbox:Shadan: Difference between revisions
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==Classification== | ==Classification== | ||
'''Classification of [[breast lumps]] based on [[epithelial hyperplasia]]<ref name="pmid16034008">{{cite journal| author=Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K et al.| title=Benign breast disease and the risk of breast cancer. | journal=N Engl J Med | year= 2005 | volume= 353 | issue= 3 | pages= 229-37 | pmid=16034008 | doi=10.1056/NEJMoa044383 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16034008 }} </ref>''' | '''Classification of [[breast lumps]] based on [[epithelial hyperplasia]]<ref name="pmid16034008">{{cite journal| author=Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K et al.| title=Benign breast disease and the risk of breast cancer. | journal=N Engl J Med | year= 2005 | volume= 353 | issue= 3 | pages= 229-37 | pmid=16034008 | doi=10.1056/NEJMoa044383 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16034008 }} </ref>''' | ||
*Approximately 65% of all | *Approximately 65% of all benign breast disease considered as [[nonproliferative]](NP)with relative cancer risk of 1.2, 1.4 times: | ||
**Simple cyst | **Simple cyst | ||
**Fibrosis | **Fibrosis | ||
| Line 29: | Line 29: | ||
** Apocrine atypia | ** Apocrine atypia | ||
** Secretory atypia | ** Secretory atypia | ||
'''Classification of [[benign breast lesion]] regarding to [[histological region]]''': | |||
*Terminal and lobular ducts | |||
**Acinar distention | |||
***Cyst | |||
**Intralobular connective tissue proliferation | |||
***Sclerosing adenosis | |||
***Fibroadenoma | |||
***Phyllodes tumor | |||
***Hamartoma | |||
**Epithelial changes in terminal duct lobaular units (TDLU) | |||
***Apocrine metaplasia | |||
***Ductal and lobular hyperplasia, usual and typical | |||
***Papillomatosis | |||
***Intracystic papilloma | |||
*Ductal system | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 16:48, 6 December 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
Classification
Classification of breast lumps based on epithelial hyperplasia[1]
- Approximately 65% of all benign breast disease considered as nonproliferative(NP)with relative cancer risk of 1.2, 1.4 times:
- Simple cyst
- Fibrosis
- Fibroadenoma (simple)
- Columnar alteration (Simple)
- Apocrine metaplasia (simple)
- Mild ductal hyperplasia
- Approximately 30% of total are classifed as proliferative disease(PD) with relative cancer risk of 1.7, 2.1 times
- Usual ductal hyperplasia
- Sclerosing adenosis
- Columnar hyperplasia
- papilloma
- Radical scar
- Approximately 5% to 8% of the rest regarded to PD with atypia with relative cancer risk more than 4 times
- Atypical lobar hyperplasia
- Lobular carcinoma in situ
- Atypical ductal hyperplasia
- Unclear risk
- Mucocele like tumor
- Apocrine atypia
- Secretory atypia
Classification of benign breast lesion regarding to histological region:
- Terminal and lobular ducts
- Acinar distention
- Cyst
- Intralobular connective tissue proliferation
- Sclerosing adenosis
- Fibroadenoma
- Phyllodes tumor
- Hamartoma
- Epithelial changes in terminal duct lobaular units (TDLU)
- Apocrine metaplasia
- Ductal and lobular hyperplasia, usual and typical
- Papillomatosis
- Intracystic papilloma
- Acinar distention
- Ductal system
References
- ↑ Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K; et al. (2005). "Benign breast disease and the risk of breast cancer". N Engl J Med. 353 (3): 229–37. doi:10.1056/NEJMoa044383. PMID 16034008.