Breast lumps differential diagnosis: Difference between revisions
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*** [[pathology]] results such as: | *** [[pathology]] results such as: | ||
****Atypical ductal [[hyperplasia]] (ADH) | ****Atypical ductal [[hyperplasia]] (ADH) | ||
****Atypical lobular hyperplasia(ALH) | ****Atypical lobular hyperplasia (ALH) | ||
****[[Lobular carcinoma in situ]](LCIS) | ****[[Lobular carcinoma in situ]] (LCIS) | ||
***Previous history of [[radiotherapy]] | ***Previous history of [[radiotherapy]] | ||
*[[Inflammatory]] lumps:<ref name="pmid3307689">{{cite journal| author=Lang AP, Luchsinger IS, Rawling EG| title=Filariasis of the breast. | journal=Arch Pathol Lab Med | year= 1987 | volume= 111 | issue= 8 | pages= 757-9 | pmid=3307689 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3307689 }} </ref><ref name="pmid8629415">{{cite journal| author=Varghese R, Raghuveer CV, Pai MR, Bansal R| title=Microfilariae in cytologic smears: a report of six cases. | journal=Acta Cytol | year= 1996 | volume= 40 | issue= 2 | pages= 299-301 | pmid=8629415 | doi=10.1159/000333755 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8629415 }} </ref> | *[[Inflammatory]] lumps:<ref name="pmid3307689">{{cite journal| author=Lang AP, Luchsinger IS, Rawling EG| title=Filariasis of the breast. | journal=Arch Pathol Lab Med | year= 1987 | volume= 111 | issue= 8 | pages= 757-9 | pmid=3307689 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3307689 }} </ref><ref name="pmid8629415">{{cite journal| author=Varghese R, Raghuveer CV, Pai MR, Bansal R| title=Microfilariae in cytologic smears: a report of six cases. | journal=Acta Cytol | year= 1996 | volume= 40 | issue= 2 | pages= 299-301 | pmid=8629415 | doi=10.1159/000333755 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8629415 }} </ref> | ||
| Line 33: | Line 33: | ||
****Non-lactational [[mastitis]] | ****Non-lactational [[mastitis]] | ||
*****Periductal [[mastitis]] in chronic smokers | *****Periductal [[mastitis]] in chronic smokers | ||
*****[[Lobular]] [[mastitis]] in tuberculosis and parasitic infection | *****[[Lobular]] [[mastitis]] in tuberculosis and [[parasitic infection]] | ||
***Non-infective lumps such as chronic [[granulomatous]] infection | ***Non-infective lumps such as [[chronic]] [[granulomatous]] [[infection]] | ||
*Solid non-inflammatory lumps <ref>Alagaratnam, T.T. & Wong, J. World J. Surg. (1989) 13: 743. https://doi.org/10.1007/BF01658425</ref> <ref name="pmid2623884">{{cite journal| author=Shukla HS, Kumar S| title=Benign breast disorders in nonwestern populations: Part II--Benign breast disorders in India. | journal=World J Surg | year= 1989 | volume= 13 | issue= 6 | pages= 746-9 | pmid=2623884 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2623884 }} </ref> | *Solid non-inflammatory lumps <ref>Alagaratnam, T.T. & Wong, J. World J. Surg. (1989) 13: 743. https://doi.org/10.1007/BF01658425</ref> <ref name="pmid2623884">{{cite journal| author=Shukla HS, Kumar S| title=Benign breast disorders in nonwestern populations: Part II--Benign breast disorders in India. | journal=World J Surg | year= 1989 | volume= 13 | issue= 6 | pages= 746-9 | pmid=2623884 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2623884 }} </ref> | ||
**Related to age, geographical area and ethnicity | **Related to age, geographical area and ethnicity | ||
Revision as of 15:16, 2 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
Breast lumps must be differentiated from other diseases such as malignancy, cysts, inflammation and non-inflammatory solid lumps.
Breast symptoms such as nipple discharge and mastalgia require assessment as well [1].
Differentiating Breast lumps from other Diseases
Differential diagnosis of breast lumps include: [1]
- Malignancy or breast cancer
- Associated with following factors:[2]
- Geographical area
- age
- Ethnicity
- Positive family history
- pathology results such as:
- Atypical ductal hyperplasia (ADH)
- Atypical lobular hyperplasia (ALH)
- Lobular carcinoma in situ (LCIS)
- Previous history of radiotherapy
- Associated with following factors:[2]
- Inflammatory lumps:[3][4]
- Associated to personal habit and disease pattern:
- Infective lumps
- Non-infective lumps such as chronic granulomatous infection
- Associated to personal habit and disease pattern:
- Solid non-inflammatory lumps [5] [6]
- Related to age, geographical area and ethnicity
- Mostly fibroadenomas in women aged 20-30 years
- Phyllodes tumor are prevalent in various centers, racial groups in different frequencies
- Cysts[7]
- Related to age and usage of hormonal replacement therapy
- Symptomatic cysts are often seen in women age 30 years to early 50 years
- If menopausaed women may be present due to hormone replacement therapy (HRT)
References
- ↑ 1.0 1.1 Cheung KL, Lam TP (2005). "Approach to a lump in the breast: a regional perspective". Asian J Surg. 28 (1): 65–70. doi:10.1016/S1015-9584(09)60264-5. PMID 15691804.
- ↑ @article{Collyar2001BreastCA, title={Breast cancer: a global perspective.}, author={Deborah E. Collyar}, journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology}, year={2001}, volume={19 18 Suppl}, pages={101S-105S} }
- ↑ Lang AP, Luchsinger IS, Rawling EG (1987). "Filariasis of the breast". Arch Pathol Lab Med. 111 (8): 757–9. PMID 3307689.
- ↑ Varghese R, Raghuveer CV, Pai MR, Bansal R (1996). "Microfilariae in cytologic smears: a report of six cases". Acta Cytol. 40 (2): 299–301. doi:10.1159/000333755. PMID 8629415.
- ↑ Alagaratnam, T.T. & Wong, J. World J. Surg. (1989) 13: 743. https://doi.org/10.1007/BF01658425
- ↑ Shukla HS, Kumar S (1989). "Benign breast disorders in nonwestern populations: Part II--Benign breast disorders in India". World J Surg. 13 (6): 746–9. PMID 2623884.
- ↑ Leung TN, Haines CJ, Chung TK (2001). "Five-year compliance with hormone replacement therapy in postmenopausal Chinese women in Hong Kong". Maturitas. 39 (3): 195–201. PMID 11574178.