Merkel cell cancer classification

Merkel cell cancer Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Overview

Mercell cell carcinoma is classified into 3 subgroups: trabecular, intermediate, and small cell.

Classification

Histologically, MCC has been classified into three distinct subtypes:

• Trabecular: classic pattern, large-cell type, high density or granules on ultrasound examination.
• Intermediate: solid pattern (most common).
• Small cell: diffuse, few high density granules on ultrasound examination (second most common).

Subtype	Pattern	Anatomical studies
Trabecular type	Classic pattern	large-cells High density granules
Intermediate type	Solid pattern	Most common
Small cell type	Diffuse pattern	Few high density granules