Burkitt's lymphoma natural history, complications and prognosis: Difference between revisions
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The prognosis varies with the age, children have the most favorable prognosis. Burkitt's lymphoma in children is associated with a 5 year survival rate of 90%. The presence of metastasis in [[bone marrow]] or [[CNS]] is associated with a particularly poor prognosis among patients with Burkitt's lymphoma. | The prognosis varies with the age, children have the most favorable prognosis. Burkitt's lymphoma in children is associated with a 5 year survival rate of 90%. The presence of metastasis in [[bone marrow]] or [[CNS]] is associated with a particularly poor prognosis among patients with Burkitt's lymphoma. | ||
==Complications== | ==Complications== | ||
Common complications of burkitt's lymphoma include: | |||
*Disruption of teeth | |||
*Partial obstruction of airway<ref name="pmid23497670">{{cite journal| author=Aslan G| title=Unusual presentation of sporadic Burkitt's lymphoma originating from the nasal septum: a case report. | journal=J Med Case Rep | year= 2013 | volume= 7 | issue= | pages= 60 | pmid=23497670 | doi=10.1186/1752-1947-7-60 | pmc=3599746 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23497670 }} </ref> | |||
**Ulceration and drianage | **Ulceration and drianage | ||
**Tumor lysis syndrome | **Tumor lysis syndrome | ||
Revision as of 22:14, 8 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
The prognosis varies with the age, children have the most favorable prognosis. Burkitt's lymphoma in children is associated with a 5 year survival rate of 90%. The presence of metastasis in bone marrow or CNS is associated with a particularly poor prognosis among patients with Burkitt's lymphoma.
Complications
Common complications of burkitt's lymphoma include:
- Disruption of teeth
- Partial obstruction of airway[1]
- Ulceration and drianage
- Tumor lysis syndrome
Prognosis
- In children, prognosis is good with survival rates >90%[2]
- In adults, prognosis is poor, with a 5-year survival rate of 50% and is even worse with bone marrow or CNS involvement (>30% 5-year survival rate).
References
- ↑ Aslan G (2013). "Unusual presentation of sporadic Burkitt's lymphoma originating from the nasal septum: a case report". J Med Case Rep. 7: 60. doi:10.1186/1752-1947-7-60. PMC 3599746. PMID 23497670.
- ↑ Jacobson C, LaCasce A (2014). "How I treat Burkitt lymphoma in adults". Blood. 124 (19): 2913–20. doi:10.1182/blood-2014-06-538504. PMID 25258344.