Cugbp elav-like family member 6

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

CUGBP Elav-like family member 6 is a protein that in humans is encoded by the CELF6 gene.

Function

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010].

Further reading

• Ladd AN, Nguyen NH, Malhotra K, Cooper TA (April 2004). "CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing". J. Biol. Chem. 279 (17): 17756–64. doi:10.1074/jbc.M310687200. PMID 14761971.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.