Burkitt's lymphoma natural history, complications and prognosis: Difference between revisions
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*Disruption of teeth | *Disruption of teeth | ||
*Partial obstruction of airway<ref name="pmid23497670">{{cite journal| author=Aslan G| title=Unusual presentation of sporadic Burkitt's lymphoma originating from the nasal septum: a case report. | journal=J Med Case Rep | year= 2013 | volume= 7 | issue= | pages= 60 | pmid=23497670 | doi=10.1186/1752-1947-7-60 | pmc=3599746 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23497670 }} </ref> | *Partial obstruction of airway<ref name="pmid23497670">{{cite journal| author=Aslan G| title=Unusual presentation of sporadic Burkitt's lymphoma originating from the nasal septum: a case report. | journal=J Med Case Rep | year= 2013 | volume= 7 | issue= | pages= 60 | pmid=23497670 | doi=10.1186/1752-1947-7-60 | pmc=3599746 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23497670 }} </ref> | ||
*Ulceration and drianage | *Ulceration and drianage<ref name="pmid25289138">{{cite journal| author=Madabhavi I, Patel A, Revannasiddaiah S, Choudhary M, Anand A, Das P et al.| title=Primary esophageal Burkitt's lymphoma: a rare case report and review of literature. | journal=Gastroenterol Hepatol Bed Bench | year= 2014 | volume= 7 | issue= 4 | pages= 230-7 | pmid=25289138 | doi= | pmc=4185878 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25289138 }} </ref> | ||
*Tumor lysis syndrome<ref name="pmid12634948">{{cite journal| author=Wössmann W, Schrappe M, Meyer U, Zimmermann M, Reiter A| title=Incidence of tumor lysis syndrome in children with advanced stage Burkitt's lymphoma/leukemia before and after introduction of prophylactic use of urate oxidase. | journal=Ann Hematol | year= 2003 | volume= 82 | issue= 3 | pages= 160-5 | pmid=12634948 | doi=10.1007/s00277-003-0608-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12634948 }} </ref> | *Tumor lysis syndrome<ref name="pmid12634948">{{cite journal| author=Wössmann W, Schrappe M, Meyer U, Zimmermann M, Reiter A| title=Incidence of tumor lysis syndrome in children with advanced stage Burkitt's lymphoma/leukemia before and after introduction of prophylactic use of urate oxidase. | journal=Ann Hematol | year= 2003 | volume= 82 | issue= 3 | pages= 160-5 | pmid=12634948 | doi=10.1007/s00277-003-0608-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12634948 }} </ref> | ||
Revision as of 14:35, 9 January 2019
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Burkitt's lymphoma Microchapters |
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Treatment |
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Burkitt's lymphoma natural history, complications and prognosis On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
The prognosis varies with the age, children have the most favorable prognosis. Burkitt's lymphoma in children is associated with a 5 year survival rate of 90%. The presence of metastasis in bone marrow or CNS is associated with a particularly poor prognosis among patients with Burkitt's lymphoma.
Complications
Common complications of burkitt's lymphoma include:
- Disruption of teeth
- Partial obstruction of airway[1]
- Ulceration and drianage[2]
- Tumor lysis syndrome[3]
Prognosis
- In children, prognosis is good with survival rates >90%[4]
- In adults, prognosis is poor, with a 5-year survival rate of 50% and is even worse with bone marrow or CNS involvement (>30% 5-year survival rate).
References
- ↑ Aslan G (2013). "Unusual presentation of sporadic Burkitt's lymphoma originating from the nasal septum: a case report". J Med Case Rep. 7: 60. doi:10.1186/1752-1947-7-60. PMC 3599746. PMID 23497670.
- ↑ Madabhavi I, Patel A, Revannasiddaiah S, Choudhary M, Anand A, Das P; et al. (2014). "Primary esophageal Burkitt's lymphoma: a rare case report and review of literature". Gastroenterol Hepatol Bed Bench. 7 (4): 230–7. PMC 4185878. PMID 25289138.
- ↑ Wössmann W, Schrappe M, Meyer U, Zimmermann M, Reiter A (2003). "Incidence of tumor lysis syndrome in children with advanced stage Burkitt's lymphoma/leukemia before and after introduction of prophylactic use of urate oxidase". Ann Hematol. 82 (3): 160–5. doi:10.1007/s00277-003-0608-2. PMID 12634948.
- ↑ Jacobson C, LaCasce A (2014). "How I treat Burkitt lymphoma in adults". Blood. 124 (19): 2913–20. doi:10.1182/blood-2014-06-538504. PMID 25258344.