Enteropathy-associated T-cell lymphoma other imaging findings: Difference between revisions
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===Other Imaging Findings | ==Overview== | ||
Enteropathy-associated T-cell Lymphoma (EATL), also enteropathy-type T-cell lymphoma (ETTL), is a type of T-cell non-hodgkin lymphoma that affects the small intestine, it is composed of large lymphoid cells. Enteropathy-associated T-cell lymphoma has two subtypes, type I enteropathy-associated T-cell lymphoma which has a strong association with celiac disease and it is more common in western countries and type II enteropathy-associated T-cell lymphoma which is mostly found among the Asian population. Genes involved in the pathogenesis of this disease include 8q24, T-cell receptor (TCR) beta and gamma, and 16q genes. On gross pathology, multiple intestinal ulcers are characteristic findings of EATL. On microscopic histopathological analysis, monotonous cells, round or angulated vesicular nuclei, and prominent nucleoli are characteristic findings of enteropathy-associated T-cell lymphoma. There are no established causes for enteropathy-associated T-cell lymphoma. EATL must be differentiated from other diseases such as peptic ulcer, poorly-differentiated adenocarcinoma, MALT lymphoma, diffuse large B cell lymphoma, and mantle cell lymphoma. | |||
==Other Imaging Findings== | |||
* Other diagnostic studies for enteropathy-associated T-cell lymphoma include:<ref name="cancer.gov">Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 26, 2016</ref><ref name="LeeIm2003">{{cite journal|last1=Lee|first1=Hyun Ju|last2=Im|first2=Jung-Gi|last3=Goo|first3=Jin Mo|last4=Kim|first4=Kyoung Won|last5=Choi|first5=Byung Ihn|last6=Chang|first6=Kee Hyun|last7=Han|first7=Joon Koo|last8=Han|first8=Moon Hee|title=Peripheral T-Cell Lymphoma: Spectrum of Imaging Findings with Clinical and Pathologic Features1|journal=RadioGraphics|volume=23|issue=1|year=2003|pages=7–26|issn=0271-5333|doi=10.1148/rg.231025018}}. Accessed on January 28, 2016</ref> | * Other diagnostic studies for enteropathy-associated T-cell lymphoma include:<ref name="cancer.gov">Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 26, 2016</ref><ref name="LeeIm2003">{{cite journal|last1=Lee|first1=Hyun Ju|last2=Im|first2=Jung-Gi|last3=Goo|first3=Jin Mo|last4=Kim|first4=Kyoung Won|last5=Choi|first5=Byung Ihn|last6=Chang|first6=Kee Hyun|last7=Han|first7=Joon Koo|last8=Han|first8=Moon Hee|title=Peripheral T-Cell Lymphoma: Spectrum of Imaging Findings with Clinical and Pathologic Features1|journal=RadioGraphics|volume=23|issue=1|year=2003|pages=7–26|issn=0271-5333|doi=10.1148/rg.231025018}}. Accessed on January 28, 2016</ref> | ||
:* [[PET]] scan | :* [[PET]] scan | ||
Revision as of 21:32, 9 January 2019
Overview
Enteropathy-associated T-cell Lymphoma (EATL), also enteropathy-type T-cell lymphoma (ETTL), is a type of T-cell non-hodgkin lymphoma that affects the small intestine, it is composed of large lymphoid cells. Enteropathy-associated T-cell lymphoma has two subtypes, type I enteropathy-associated T-cell lymphoma which has a strong association with celiac disease and it is more common in western countries and type II enteropathy-associated T-cell lymphoma which is mostly found among the Asian population. Genes involved in the pathogenesis of this disease include 8q24, T-cell receptor (TCR) beta and gamma, and 16q genes. On gross pathology, multiple intestinal ulcers are characteristic findings of EATL. On microscopic histopathological analysis, monotonous cells, round or angulated vesicular nuclei, and prominent nucleoli are characteristic findings of enteropathy-associated T-cell lymphoma. There are no established causes for enteropathy-associated T-cell lymphoma. EATL must be differentiated from other diseases such as peptic ulcer, poorly-differentiated adenocarcinoma, MALT lymphoma, diffuse large B cell lymphoma, and mantle cell lymphoma.
Other Imaging Findings
- PET scan
- Barium study
- Colonoscopy
- Findings on barium study suggestive of enteropathy-associated T-cell lymphoma include:
- Multiple aphthous ulcers
- Segmental luminal narrowing
- Finding on colonoscopy suggestive of enteropathy-associated T-cell lymphoma includes:
Refrences
- ↑ Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 26, 2016
- ↑ Lee, Hyun Ju; Im, Jung-Gi; Goo, Jin Mo; Kim, Kyoung Won; Choi, Byung Ihn; Chang, Kee Hyun; Han, Joon Koo; Han, Moon Hee (2003). "Peripheral T-Cell Lymphoma: Spectrum of Imaging Findings with Clinical and Pathologic Features1". RadioGraphics. 23 (1): 7–26. doi:10.1148/rg.231025018. ISSN 0271-5333.. Accessed on January 28, 2016