Gem-associated protein 2: Difference between revisions

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==Interactions==
==Interactions==
Gem-associated protein 2 has been shown to [[Protein-protein interaction|interact]] with [[DDX20]]<ref name=pmid11914277>{{cite journal |last=Mourelatos |first=Zissimos |authorlink= |author2=Dostie Josée |author3=Paushkin Sergey |author4=Sharma Anup |author5=Charroux Bernard |author6=Abel Linda |author7=Rappsilber Juri |author8=Mann Matthias |author9=Dreyfuss Gideon  |date=March 2002  |title=miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs |journal=Genes Dev. |volume=16 |issue=6 |pages=720–8 |publisher= |location = United States| issn = 0890-9369| pmid = 11914277 |doi = 10.1101/gad.974702 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=155365 }}</ref><ref name=pmid10601333>{{cite journal |last=Charroux |first=B |authorlink= |author2=Pellizzoni L |author3=Perkinson R A |author4=Shevchenko A |author5=Mann M |author6=Dreyfuss G  |date=December 1999  |title=Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems |journal=J. Cell Biol. |volume=147 |issue=6 |pages=1181–94 |publisher= |location = UNITED STATES| issn = 0021-9525| pmid = 10601333 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1083/jcb.147.6.1181 |pmc=2168095 }}</ref> and [[SMN1]].<ref name=pmid9323129/><ref name=pmid12668731>{{cite journal |last=Carnegie |first=Graeme K |authorlink= |author2=Sleeman Judith E |author3=Morrice Nick |author4=Hastie C James |author5=Peggie Mark W |author6=Philp Amanda |author7=Lamond Angus I |author8=Cohen Patricia T W  |date=May 2003 |title=Protein phosphatase 4 interacts with the Survival of motor neurons complex and enhances the temporal localisation of snRNPs |journal=J. Cell Sci. |volume=116 |issue=Pt 10 |pages=1905–13 |publisher= |location = England| issn = 0021-9533| pmid = 12668731 |doi = 10.1242/jcs.00409 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid10942426>{{cite journal |last=Meister |first=G |authorlink= |author2=Bühler D |author3=Laggerbauer B |author4=Zobawa M |author5=Lottspeich F |author6=Fischer U  |date=August 2000  |title=Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins |journal=Hum. Mol. Genet. |volume=9 |issue=13 |pages=1977–86 |publisher= |location = ENGLAND| issn = 0964-6906| pmid = 10942426 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1093/hmg/9.13.1977 }}</ref>
Gem-associated protein 2 has been shown to [[Protein-protein interaction|interact]] with [[DDX20]]<ref name=pmid11914277>{{cite journal |last=Mourelatos |first=Zissimos |authorlink= |author2=Dostie Josée |author3=Paushkin Sergey |author4=Sharma Anup |author5=Charroux Bernard |author6=Abel Linda |author7=Rappsilber Juri |author8=Mann Matthias |author9=Dreyfuss Gideon  |date=March 2002  |title=miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs |journal=Genes Dev. |volume=16 |issue=6 |pages=720–8 | issn = 0890-9369| pmid = 11914277 |doi = 10.1101/gad.974702 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=155365 }}</ref><ref name=pmid10601333>{{cite journal |last=Charroux |first=B |authorlink= |author2=Pellizzoni L |author3=Perkinson R A |author4=Shevchenko A |author5=Mann M |author6=Dreyfuss G  |date=December 1999  |title=Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems |journal=J. Cell Biol. |volume=147 |issue=6 |pages=1181–94 | issn = 0021-9525| pmid = 10601333 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1083/jcb.147.6.1181 |pmc=2168095 }}</ref> and [[SMN1]].<ref name=pmid9323129/><ref name=pmid12668731>{{cite journal |last=Carnegie |first=Graeme K |authorlink= |author2=Sleeman Judith E |author3=Morrice Nick |author4=Hastie C James |author5=Peggie Mark W |author6=Philp Amanda |author7=Lamond Angus I |author8=Cohen Patricia T W  |date=May 2003 |title=Protein phosphatase 4 interacts with the Survival of motor neurons complex and enhances the temporal localisation of snRNPs |journal=J. Cell Sci. |volume=116 |issue=Pt 10 |pages=1905–13 | issn = 0021-9533| pmid = 12668731 |doi = 10.1242/jcs.00409 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid10942426>{{cite journal |last=Meister |first=G |authorlink= |author2=Bühler D |author3=Laggerbauer B |author4=Zobawa M |author5=Lottspeich F |author6=Fischer U  |date=August 2000  |title=Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins |journal=Hum. Mol. Genet. |volume=9 |issue=13 |pages=1977–86 | issn = 0964-6906| pmid = 10942426 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1093/hmg/9.13.1977 }}</ref>


==See also==
==See also==
* [[Gideon Dreyfuss]]
* [[Gideon Dreyfuss]]
* [[Survival of motor neuron]]
* [[Spinal muscular atrophy]]
* [[SMN1]]


==References==
==References==
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*{{cite journal  |vauthors=Aerbajinai W, Ishihara T, Arahata K, Tsukahara T |title=Increased expression level of the splicing variant of SIP1 in motor neuron diseases |journal=Int. J. Biochem. Cell Biol. |volume=34 |issue= 6 |pages= 699–707 |year= 2002 |pmid= 11943600 |doi=10.1016/S1357-2725(01)00150-9  }}
*{{cite journal  |vauthors=Aerbajinai W, Ishihara T, Arahata K, Tsukahara T |title=Increased expression level of the splicing variant of SIP1 in motor neuron diseases |journal=Int. J. Biochem. Cell Biol. |volume=34 |issue= 6 |pages= 699–707 |year= 2002 |pmid= 11943600 |doi=10.1016/S1357-2725(01)00150-9  }}
*{{cite journal  |vauthors=Baccon J, Pellizzoni L, Rappsilber J, etal |title=Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 31957–62 |year= 2002 |pmid= 12065586 |doi= 10.1074/jbc.M203478200 }}
*{{cite journal  |vauthors=Baccon J, Pellizzoni L, Rappsilber J, etal |title=Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 31957–62 |year= 2002 |pmid= 12065586 |doi= 10.1074/jbc.M203478200 }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M }}
}}
}}
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Revision as of 17:56, 7 November 2018

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
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RefSeq (protein)

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Wikidata
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Gem-associated protein 2 (GEMIN2), also called survival of motor neuron protein-interacting protein 1 (SIP1), is a protein that in humans is encoded by the GEMIN2 gene.[1][2][3]


Interactions

Gem-associated protein 2 has been shown to interact with DDX20[4][5] and SMN1.[2][6][7]

See also

References

  1. ↑ Fischer U, Liu Q, Dreyfuss G (October 1997). "The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis". Cell. 90 (6): 1023–9. doi:10.1016/S0092-8674(00)80368-2. PMID 9323130.
  2. ↑ 2.0 2.1 Liu Q, Fischer U, Wang F, Dreyfuss G (October 1997). "The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins". Cell. 90 (6): 1013–21. doi:10.1016/S0092-8674(00)80367-0. PMID 9323129.
  3. ↑ "Entrez Gene: SIP1 survival of motor neuron protein interacting protein 1".
  4. ↑ Mourelatos, Zissimos; Dostie Josée; Paushkin Sergey; Sharma Anup; Charroux Bernard; Abel Linda; Rappsilber Juri; Mann Matthias; Dreyfuss Gideon (March 2002). "miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs". Genes Dev. 16 (6): 720–8. doi:10.1101/gad.974702. ISSN 0890-9369. PMC 155365. PMID 11914277.
  5. ↑ Charroux, B; Pellizzoni L; Perkinson R A; Shevchenko A; Mann M; Dreyfuss G (December 1999). "Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems". J. Cell Biol. 147 (6): 1181–94. doi:10.1083/jcb.147.6.1181. ISSN 0021-9525. PMC 2168095. PMID 10601333.
  6. ↑ Carnegie, Graeme K; Sleeman Judith E; Morrice Nick; Hastie C James; Peggie Mark W; Philp Amanda; Lamond Angus I; Cohen Patricia T W (May 2003). "Protein phosphatase 4 interacts with the Survival of motor neurons complex and enhances the temporal localisation of snRNPs". J. Cell Sci. 116 (Pt 10): 1905–13. doi:10.1242/jcs.00409. ISSN 0021-9533. PMID 12668731.
  7. ↑ Meister, G; Bühler D; Laggerbauer B; Zobawa M; Lottspeich F; Fischer U (August 2000). "Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins". Hum. Mol. Genet. 9 (13): 1977–86. doi:10.1093/hmg/9.13.1977. ISSN 0964-6906. PMID 10942426.

Further reading



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