Allograft inflammatory factor 1-like: Difference between revisions
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'''Allograft inflammatory factor 1-like'''(AIF1L) is a [[protein]] that is encoded by the ''AIF1L'' [[gene]] in humans.<ref name="pmid11230166">{{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Res | volume = 11 | issue = 3 | pages = 422–35 |date=Mar 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: C9orf58 chromosome 9 open reading frame 58| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83543| accessdate = }}</ref> | '''Allograft inflammatory factor 1-like'''(AIF1L) is a [[protein]] that is encoded by the ''AIF1L'' [[gene]] in [[Human|humans]].<ref name="pmid11230166">{{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Res | volume = 11 | issue = 3 | pages = 422–35 |date=Mar 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: C9orf58 chromosome 9 open reading frame 58| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83543| accessdate = }}</ref> | ||
AIF1L is an [[actin]]-binding protein that promotes actin bundling. It may neither bind [[calcium]] nor depend on calcium for function.<ref>{{cite web|title=Aif1l - Allograft inflammatory factor 1-like - Mus musculus (Mouse) - Aif1l gene & protein|url= | AIF1L is an [[actin]]-binding protein that promotes actin bundling. It may neither bind [[calcium]] nor depend on calcium for function.<ref>{{cite web|title=Aif1l - Allograft inflammatory factor 1-like - Mus musculus (Mouse) - Aif1l gene & protein|url=https://www.uniprot.org/uniprot/Q9EQX4|website=www.uniprot.org|accessdate=3 December 2017|language=en}}</ref> It has biased expression in [[kidney]] (RPKM 130.1), [[spleen]] (RPKM 121.3) and 8 other tissues.<ref>{{cite web|title=AIF1L allograft inflammatory factor 1 like [Homo sapiens (human)] - Gene - NCBI|url=https://www.ncbi.nlm.nih.gov/gene/83543#gene-expression|website=www.ncbi.nlm.nih.gov|accessdate=3 December 2017}}</ref> | ||
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Revision as of 02:45, 24 March 2018
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Allograft inflammatory factor 1-like(AIF1L) is a protein that is encoded by the AIF1L gene in humans.[1][2]
AIF1L is an actin-binding protein that promotes actin bundling. It may neither bind calcium nor depend on calcium for function.[3] It has biased expression in kidney (RPKM 130.1), spleen (RPKM 121.3) and 8 other tissues.[4]
References
- ↑ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- ↑ "Entrez Gene: C9orf58 chromosome 9 open reading frame 58".
- ↑ "Aif1l - Allograft inflammatory factor 1-like - Mus musculus (Mouse) - Aif1l gene & protein". www.uniprot.org. Retrieved 3 December 2017.
- ↑ "AIF1L allograft inflammatory factor 1 like [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 3 December 2017.
External links
- Human AIF1L genome location and AIF1L gene details page in the UCSC Genome Browser.
Further reading
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
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