Dendrocyte expressed seven transmembrane protein: Difference between revisions

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{{Underlinked|date=September 2014}}
{{Infobox_gene}}
{{Infobox_gene}}
'''Dendrocyte expressed seven transmembrane protein''' is a [[protein]] that in humans is encoded by the DCSTAMP [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: Dendrocyte expressed seven transmembrane protein | url = https://www.ncbi.nlm.nih.gov/gene/81501 }}</ref>


'''Dendrocyte expressed seven transmembrane protein''' is a [[protein]] that in humans is encoded by the DCSTAMP [[gene]].
== Function ==
<ref name="entrez">
{{cite web
| title = Entrez Gene: Dendrocyte expressed seven transmembrane protein
| url = https://www.ncbi.nlm.nih.gov/gene/81501
| accessdate = 2014-09-11 <!-- T11:11:52.305219-08:00 -->
}}</ref>
 
==Function==


This gene encodes a seven-pass [[transmembrane]] protein that is primarily expressed in [[Dendrite (non-neuronal)|dendritic]] cells. The encoded protein is involved in a range of [[Immunology|immunological]] functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and [[myeloid]] differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012].
This gene encodes a seven-pass [[transmembrane]] protein that is primarily expressed in [[Dendrite (non-neuronal)|dendritic]] cells. The encoded protein is involved in a range of [[Immunology|immunological]] functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and [[myeloid]] differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012].


== References ==
== References ==
{{reflist}}
{{reflist}}


== Further reading ==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
*{{Cite journal
* {{cite journal | vauthors = Lee KY, Huang SM, Li S, Kim JM | title = Identification of differentially expressed genes in papillary thyroid cancers | journal = Yonsei Medical Journal | volume = 50 | issue = 1 | pages = 60–7 | date = February 2009 | pmid = 19259350 | pmc = 2649849 | doi = 10.3349/ymj.2009.50.1.60 }}
| pmid = 19259350
* {{cite journal | vauthors = Sakai H, Okafuji I, Nishikomori R, Abe J, Izawa K, Kambe N, Yasumi T, Nakahata T, Heike T | title = The CD40-CD40L axis and IFN-γ play critical roles in Langhans giant cell formation | journal = International Immunology | volume = 24 | issue = 1 | pages = 5–15 | date = January 2012 | pmid = 22058328 | doi = 10.1093/intimm/dxr088 }}
| pmc = 2649849
* {{cite journal | vauthors = Eleveld-Trancikova D, Triantis V, Moulin V, Looman MW, Wijers M, Fransen JA, Lemckert AA, Havenga MJ, Figdor CG, Janssen RA, Adema GJ | title = The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum | journal = Journal of Leukocyte Biology | volume = 77 | issue = 3 | pages = 337–43 | date = March 2005 | pmid = 15601667 | doi = 10.1189/jlb.0804441 }}
| year = 2009
* {{cite journal | vauthors = Beauregard M, Gagnon E, Guay-Bélanger S, Morissette J, Brown JP, Michou L | title = Identification of rare genetic variants in novel loci associated with Paget's disease of bone | journal = Human Genetics | volume = 133 | issue = 6 | pages = 755–68 | date = June 2014 | pmid = 24370779 | doi = 10.1007/s00439-013-1409-x }}
| author1 = Lee
* {{cite journal | vauthors = Kim HY, Cho S, Yu J, Sung S, Kim H | title = Analysis of copy number variation in 8,842 Korean individuals reveals 39 genes associated with hepatic biomarkers AST and ALT | journal = BMB Reports | volume = 43 | issue = 8 | pages = 547–53 | date = August 2010 | pmid = 20797317 }}
| first1 = K. Y.
* {{cite journal | vauthors = Eleveld-Trancikova D, Sanecka A, van Hout-Kuijer MA, Looman MW, Hendriks IA, Jansen BJ, Adema GJ | title = DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation | journal = Molecular Immunology | volume = 47 | issue = 11–12 | pages = 1963–73 | date = July 2010 | pmid = 20546900 | doi = 10.1016/j.molimm.2010.04.019 }}
| title = Identification of differentially expressed genes in papillary thyroid cancers
* {{cite journal | vauthors = Zeng Z, Zhang C, Chen J | title = Lentivirus-mediated RNA interference of DC-STAMP expression inhibits the fusion and resorptive activity of human osteoclasts | journal = Journal of Bone and Mineral Metabolism | volume = 31 | issue = 4 | pages = 409–16 | date = July 2013 | pmid = 23525827 | doi = 10.1007/s00774-013-0434-0 }}
| journal = Yonsei Medical Journal
* {{cite journal | vauthors = Hartgers FC, Looman MW, van der Woning B, Merkx GF, Figdor CG, Adema GJ | title = Genomic organization, chromosomal localization, and 5' upstream region of the human DC-STAMP gene | journal = Immunogenetics | volume = 53 | issue = 2 | pages = 145–9 | date = March 2001 | pmid = 11345591 | doi = 10.1007/s002510100302 }}
| volume = 50
* {{cite journal | vauthors = Chiu YH, Mensah KA, Schwarz EM, Ju Y, Takahata M, Feng C, McMahon LA, Hicks DG, Panepento B, Keng PC, Ritchlin CT | title = Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP) | journal = Journal of Bone and Mineral Research | volume = 27 | issue = 1 | pages = 79–92 | date = January 2012 | pmid = 21987375 | pmc = 3304467 | doi = 10.1002/jbmr.531 }}
| issue = 1
| pages = 60–7
| last2 = Huang
| first2 = S. M.
| last3 = Li
| first3 = S
| last4 = Kim
| first4 = J. M.
| doi = 10.3349/ymj.2009.50.1.60
}}
*{{Cite journal
| pmid = 22058328
| year = 2012
| author1 = Sakai
| first1 = H
| title = The CD40-CD40L axis and IFN-γ play critical roles in Langhans giant cell formation
| journal = International Immunology
| volume = 24
| issue = 1
| pages = 5–15
| last2 = Okafuji
| first2 = I
| last3 = Nishikomori
| first3 = R
| last4 = Abe
| first4 = J
| last5 = Izawa
| first5 = K
| last6 = Kambe
| first6 = N
| last7 = Yasumi
| first7 = T
| last8 = Nakahata
| first8 = T
| last9 = Heike
| first9 = T
| doi = 10.1093/intimm/dxr088
 
}}
*{{Cite journal
| pmid = 15601667
| year = 2005
| author1 = Eleveld-Trancikova
| first1 = D
| title = The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum
| journal = Journal of Leukocyte Biology
| volume = 77
| issue = 3
| pages = 337–43
| last2 = Triantis
| first2 = V
| last3 = Moulin
| first3 = V
| last4 = Looman
| first4 = M. W.
| last5 = Wijers
| first5 = M
| last6 = Fransen
| first6 = J. A.
| last7 = Lemckert
| first7 = A. A.
| last8 = Havenga
| first8 = M. J.
| last9 = Figdor
| first9 = C. G.
| last10 = Janssen
| first10 = R. A.
| last11 = Adema
| first11 = G. J.
| doi = 10.1189/jlb.0804441
}}
*{{Cite journal
| pmid = 24370779
| year = 2014
| author1 = Beauregard
| first1 = M
| title = Identification of rare genetic variants in novel loci associated with Paget's disease of bone
| journal = Human Genetics
| volume = 133
| issue = 6
| pages = 755–68
| last2 = Gagnon
| first2 = E
| last3 = Guay-Bélanger
| first3 = S
| last4 = Morissette
| first4 = J
| last5 = Brown
| first5 = J. P.
| last6 = Michou
| first6 = L
| doi = 10.1007/s00439-013-1409-x
}}
*{{Cite journal
| pmid = 20797317
| year = 2010
| author1 = Kim
| first1 = H. Y.
| title = Analysis of copy number variation in 8,842 Korean individuals reveals 39 genes associated with hepatic biomarkers AST and ALT
| journal = BMB reports
| volume = 43
| issue = 8
| pages = 547–53
| last2 = Cho
| first2 = S
| last3 = Yu
| first3 = J
| last4 = Sung
| first4 = S
| last5 = Kim
| first5 = H
}}
*{{Cite journal
| pmid = 20546900
| year = 2010
| author1 = Eleveld-Trancikova
| first1 = D
| title = DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation
| journal = Molecular Immunology
| volume = 47
| issue = 11–12
| pages = 1963–73
| last2 = Sanecka
| first2 = A
| last3 = Van Hout-Kuijer
| first3 = M. A.
| last4 = Looman
| first4 = M. W.
| last5 = Hendriks
| first5 = I. A.
| last6 = Jansen
| first6 = B. J.
| last7 = Adema
| first7 = G. J.
| doi = 10.1016/j.molimm.2010.04.019
}}
*{{Cite journal
| pmid = 23525827
| year = 2013
| author1 = Zeng
| first1 = Z
| title = Lentivirus-mediated RNA interference of DC-STAMP expression inhibits the fusion and resorptive activity of human osteoclasts
| journal = Journal of Bone and Mineral Metabolism
| volume = 31
| issue = 4
| pages = 409–16
| last2 = Zhang
| first2 = C
| last3 = Chen
| first3 = J
| doi = 10.1007/s00774-013-0434-0
}}
*{{Cite journal
| pmid = 11345591
| year = 2001
| author1 = Hartgers
| first1 = F. C.
| title = Genomic organization, chromosomal localization, and 5' upstream region of the human DC-STAMP gene
| journal = Immunogenetics
| volume = 53
| issue = 2
| pages = 145–9
| last2 = Looman
| first2 = M. W.
| last3 = Van Der Woning
| first3 = B
| last4 = Merkx
| first4 = G. F.
| last5 = Figdor
| first5 = C. G.
| last6 = Adema
| first6 = G. J.
| doi=10.1007/s002510100302
}}
*{{Cite journal
| pmid = 21987375
| pmc = 3304467
| year = 2012
| author1 = Chiu
| first1 = Y. H.
| title = Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP)
| journal = Journal of Bone and Mineral Research
| volume = 27
| issue = 1
| pages = 79–92
| last2 = Mensah
| first2 = K. A.
| last3 = Schwarz
| first3 = E. M.
| last4 = Ju
| first4 = Y
| last5 = Takahata
| first5 = M
| last6 = Feng
| first6 = C
| last7 = McMahon
| first7 = L. A.
| last8 = Hicks
| first8 = D. G.
| last9 = Panepento
| first9 = B
| last10 = Keng
| first10 = P. C.
| last11 = Ritchlin
| first11 = C. T.
| doi = 10.1002/jbmr.531
}}
 
{{refend}}
{{refend}}


{{NLM content}}
{{NLM content}}


{{gene-8-stub}}
{{gene-8-stub}}

Revision as of 21:15, 29 January 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Dendrocyte expressed seven transmembrane protein is a protein that in humans is encoded by the DCSTAMP gene.[1]

Function

This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012].

References

  1. ↑ "Entrez Gene: Dendrocyte expressed seven transmembrane protein".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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