MicroRNA 5680: Difference between revisions

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

VisualWikitext

Revision as of 21:10, 27 May 2018

MicroRNA 5680 is a protein that in humans is encoded by the MIR5680 gene. ^[1]

Function

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

References

↑ "Entrez Gene: MicroRNA 5680". Retrieved 2016-05-09.

@@ Line 1: / Line 1: @@
-{{Multiple issues|
-{{Underlinked|date=September 2017}}
 {{Orphan|date=September 2017}}
-}}
 {{Infobox_gene}}
@@ Line 16: / Line 13: @@
 ==Function==
-microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.
+[[MicroRNA|microRNAs]] (miRNAs) are short (20-24 nt) [[Non-coding RNA|non-coding RNAs]] that are involved in post-transcriptional regulation of [[gene expression]] in multicellular organisms by affecting both the stability and translation of [[Messenger RNA|mRNAs]]. miRNAs are transcribed by [[RNA polymerase II]] as part of capped and polyadenylated [[Primary transcript|primary transcripts]] (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the [[Drosha ribonuclease III]] enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic [[Dicer ribonuclease]] to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a [[RNA-induced silencing complex]] (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The [[RefSeq]] represents the predicted microRNA stem-loop.
 == References ==

MicroRNA 5680: Difference between revisions

Revision as of 21:10, 27 May 2018

Function

References

Further reading

Navigation menu