Mu hemoglobin: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
(Rephrase) |
||
| Line 18: | Line 18: | ||
|LocusSupplementaryData= | |LocusSupplementaryData= | ||
}} | }} | ||
'''Mu hemoglobin''' is a | '''Mu hemoglobin''' is a [[Open_reading_frame#ORF_Predictor|predicted]] protein encoded in the ''HBM'' [[gene]]. The mRNA is expressed at moderate levels, but the protein has not been detected by mass spectrometry.<ref name="pmid2649166">{{cite journal | vauthors = Higgs DR, Vickers MA, Wilkie AO, Pretorius IM, Jarman AP, Weatherall DJ | title = A review of the molecular genetics of the human alpha-globin gene cluster | journal = Blood | volume = 73 | issue = 5 | pages = 1081–104 |date=April 1989 | pmid = 2649166 | doi = | url = http://www.bloodjournal.org/cgi/pmidlookup?view=long&pmid=2649166 | issn = }}</ref><ref name="pmid2825132">{{cite journal |vauthors=Fischel-Ghodsian N, Nicholls RD, Higgs DR | title = Unusual features of CpG-rich (HTF) islands in the human alpha globin complex: association with non-functional pseudogenes and presence within the 3' portion of the zeta gene | journal = Nucleic Acids Res. | volume = 15 | issue = 22 | pages = 9215–25 |date=November 1987 | pmid = 2825132 | pmc = 306463 | doi = 10.1093/nar/15.22.9215| url = http://nar.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=2825132 | issn = }}</ref><ref name="pmid15855277">{{cite journal |vauthors=Goh SH, Lee YT, Bhanu NV, etal |title=A newly discovered human alpha-globin gene |journal=Blood |volume=106 |issue=4 |pages=1466–72 |date=August 2005 |pmid=15855277 |pmc=1895206 |doi=10.1182/blood-2005-03-0948 |url=http://www.bloodjournal.org/cgi/pmidlookup?view=long&pmid=15855277}}</ref> The order of genes is: 5' - [[Hemoglobin subunit zeta|zeta]] - pseudozeta - '''mu''' - pseudoalpha-1 - [[HBA2|alpha-2]] - [[Hemoglobin, alpha 1|alpha-1]] - [[HBQ1|theta1]] - 3'. | ||
==References== | ==References== | ||
Revision as of 12:06, 28 July 2018
| hemoglobin, mu | |
|---|---|
| Identifiers | |
| Symbol | HBM |
| Alt. symbols | HBAP2 |
| Entrez | 3042 |
| HUGO | 4826 |
| OMIM | 609639 |
| RefSeq | NM_001003938 |
| UniProt | Q6B0K9 |
| Other data | |
| Locus | Chr. 16 p13.3 |
Mu hemoglobin is a predicted protein encoded in the HBM gene. The mRNA is expressed at moderate levels, but the protein has not been detected by mass spectrometry.[1][2][3] The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta1 - 3'.
References
- ↑ Higgs DR, Vickers MA, Wilkie AO, Pretorius IM, Jarman AP, Weatherall DJ (April 1989). "A review of the molecular genetics of the human alpha-globin gene cluster". Blood. 73 (5): 1081–104. PMID 2649166.
- ↑ Fischel-Ghodsian N, Nicholls RD, Higgs DR (November 1987). "Unusual features of CpG-rich (HTF) islands in the human alpha globin complex: association with non-functional pseudogenes and presence within the 3' portion of the zeta gene". Nucleic Acids Res. 15 (22): 9215–25. doi:10.1093/nar/15.22.9215. PMC 306463. PMID 2825132.
- ↑ Goh SH, Lee YT, Bhanu NV, et al. (August 2005). "A newly discovered human alpha-globin gene". Blood. 106 (4): 1466–72. doi:10.1182/blood-2005-03-0948. PMC 1895206. PMID 15855277.
| Stub icon | This genetics article is a stub. You can help Wikipedia by expanding it. |
