PDF (gene): Difference between revisions
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'''Peptide deformylase, mitochondrial''' is an [[enzyme]] that in humans is encoded by the ''PDF'' [[gene]].<ref name="pmid11060042">{{cite journal | vauthors = Giglione C, Serero A, Pierre M, Boisson B, Meinnel T | title = Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms | journal = EMBO J | volume = 19 | issue = 21 | pages = 5916–29 |date=Nov 2000 | pmid = 11060042 | pmc = 305796 | doi = 10.1093/emboj/19.21.5916 }}</ref><ref name="pmid15489958">{{cite journal | vauthors = Lee MD, She Y, Soskis MJ, Borella CP, Gardner JR, Hayes PA, Dy BM, Heaney ML, Philips MR, Bornmann WG, Sirotnak FM, Scheinberg DA | title = Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics | journal = J Clin Invest | volume = 114 | issue = 8 | pages = 1107–16 |date=Oct 2004 | pmid = 15489958 | pmc = 522256 | doi = 10.1172/JCI22269 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PDF peptide deformylase (mitochondrial)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64146| accessdate = }}</ref> | '''Peptide deformylase, mitochondrial''' is an [[enzyme]] that in humans is encoded by the ''PDF'' [[gene]].<ref name="pmid11060042">{{cite journal | vauthors = Giglione C, Serero A, Pierre M, Boisson B, Meinnel T | title = Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms | journal = EMBO J | volume = 19 | issue = 21 | pages = 5916–29 |date=Nov 2000 | pmid = 11060042 | pmc = 305796 | doi = 10.1093/emboj/19.21.5916 }}</ref><ref name="pmid15489958">{{cite journal | vauthors = Lee MD, She Y, Soskis MJ, Borella CP, Gardner JR, Hayes PA, Dy BM, Heaney ML, Philips MR, Bornmann WG, Sirotnak FM, Scheinberg DA | title = Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics | journal = J Clin Invest | volume = 114 | issue = 8 | pages = 1107–16 |date=Oct 2004 | pmid = 15489958 | pmc = 522256 | doi = 10.1172/JCI22269 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PDF peptide deformylase (mitochondrial)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64146| accessdate = }}</ref> | ||
Revision as of 15:16, 14 February 2018
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Peptide deformylase, mitochondrial is an enzyme that in humans is encoded by the PDF gene.[1][2][3]
See also
References
- ↑ Giglione C, Serero A, Pierre M, Boisson B, Meinnel T (Nov 2000). "Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms". EMBO J. 19 (21): 5916–29. doi:10.1093/emboj/19.21.5916. PMC 305796. PMID 11060042.
- ↑ Lee MD, She Y, Soskis MJ, Borella CP, Gardner JR, Hayes PA, Dy BM, Heaney ML, Philips MR, Bornmann WG, Sirotnak FM, Scheinberg DA (Oct 2004). "Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics". J Clin Invest. 114 (8): 1107–16. doi:10.1172/JCI22269. PMC 522256. PMID 15489958.
- ↑ "Entrez Gene: PDF peptide deformylase (mitochondrial)".
Further reading
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Lee MD, Antczak C, Li Y, et al. (2004). "A new human peptide deformylase inhibitable by actinonin". Biochem. Biophys. Res. Commun. 312 (2): 309–15. doi:10.1016/j.bbrc.2003.10.123. PMID 14637138.
- Serero A, Giglione C, Sardini A, et al. (2004). "An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway". J. Biol. Chem. 278 (52): 52953–63. doi:10.1074/jbc.M309770200. PMID 14532271.
- Nguyen KT, Hu X, Colton C, et al. (2003). "Characterization of a human peptide deformylase: implications for antibacterial drug design". Biochemistry. 42 (33): 9952–8. doi:10.1021/bi0346446. PMID 12924944.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Chagnon P, Michaud J, Mitchell G, et al. (2003). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis". Am. J. Hum. Genet. 71 (6): 1443–9. doi:10.1086/344580. PMC 378590. PMID 12417987.
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