Spondin 1: Difference between revisions

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{{Infobox_gene}}
{{Infobox_gene}}
'''Spondin-1''' (also known as F-spondin) is a [[protein]] that in humans is encoded by the ''SPON1'' [[gene]].<ref name="pmid9872452">{{cite journal |vauthors=Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 5 | issue = 5 | pages = 277–86 | date = Apr 1999| pmid = 9872452 | pmc =  | doi =10.1093/dnares/5.5.277  }}</ref> It is secreted by cells of the [[floor plate]] and may be involved in [[axon guidance]]<ref name="entrez">{{cite web | title = Entrez Gene: SPON1 spondin 1, extracellular matrix protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10418| accessdate = }}</ref> The protein contains 807 aminoacids and is structurally composed of six [[thrombospondin]] domains, one [[reelin]] domain, and one spondin domain.
'''Spondin-1''' (also known as F-spondin) is a [[protein]] that in humans is encoded by the ''SPON1'' [[gene]].<ref name="pmid9872452">{{cite journal |vauthors=Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 5 | issue = 5 | pages = 277–86 | date = Apr 1999| pmid = 9872452 | pmc =  | doi =10.1093/dnares/5.5.277  }}</ref> It is secreted by cells of the [[floor plate]] and may be involved in [[axon guidance]]<ref name="entrez">{{cite web | title = Entrez Gene: SPON1 spondin 1, extracellular matrix protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10418| accessdate = }}</ref> The protein contains 807 amino acids and is structurally composed of six [[thrombospondin]] domains, one [[reelin]] domain, and one spondin domain.


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Latest revision as of 14:36, 13 September 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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Wikidata
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Spondin-1 (also known as F-spondin) is a protein that in humans is encoded by the SPON1 gene.[1] It is secreted by cells of the floor plate and may be involved in axon guidance[2] The protein contains 807 amino acids and is structurally composed of six thrombospondin domains, one reelin domain, and one spondin domain.


References

  1. ↑ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
  2. ↑ "Entrez Gene: SPON1 spondin 1, extracellular matrix protein".

Further reading


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