AHNAK: Difference between revisions

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{{Infobox_gene}}
{{Infobox_gene}}
'''Neuroblast differentiation-associated protein AHNAK''', also known as desmoyokin, is a [[protein]] that in humans is encoded by the ''AHNAK'' [[gene]].<ref name="pmid7987395">{{cite journal | vauthors = James MR, ((Richard CW III)), Schott JJ, Yousry C, Clark K, Bell J, Terwilliger JD, Hazan J, Dubay C, Vignal A | title = A radiation hybrid map of 506 STS markers spanning human chromosome 11 | journal = Nat Genet | volume = 8 | issue = 1 | pages = 70–6 |date=Jan 1995 | pmid = 7987395 | pmc =  | doi = 10.1038/ng0994-70 |display-authors=etal}}</ref><ref name="pmid12153988">{{cite journal |vauthors=Hohaus A, Person V, Behlke J, Schaper J, Morano I, Haase H | title = The carboxyl-terminal region of ahnak provides a link between cardiac L-type Ca2+ channels and the actin-based cytoskeleton | journal = FASEB J | volume = 16 | issue = 10 | pages = 1205–16 |date=Aug 2002 | pmid = 12153988 | pmc =  | doi = 10.1096/fj.01-0855com }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: AHNAK AHNAK nucleoprotein (desmoyokin)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79026| accessdate = }}</ref> AHNAK was originally identified in 1989 (in [[Bovinae|bovine]] muzzle [[Epidermis (skin)|epidermal]] cells) and named desmoyokin due to its localization pattern (that resembled a [[yoke]]) in the [[Desmosome|desmosomal]] plaque.<ref name="pmid2677021">{{cite journal |vauthors=Hieda Y, Tsukita S, Tsukita S | title = A new high molecular mass protein showing unique localization in desmosomal plaque. | journal = J. Cell Biol. | volume = 109 | issue = 4 | pages = 1511–1518 |date=Oct 1989 | pmid = 2677021 | pmc = 2115823 | doi=10.1083/jcb.109.4.1511}}</ref> AHNAK has been shown to be essential for [[Pseudopodia|pseudopod]] protrusion and cell [[Cell migration|migration]].  
'''Neuroblast differentiation-associated protein AHNAK''', also known as desmoyokin, is a [[protein]] that in humans is encoded by the ''AHNAK'' [[gene]].<ref name="pmid7987395">{{cite journal | vauthors = James MR, Richard CW, Schott JJ, Yousry C, Clark K, Bell J, Terwilliger JD, Hazan J, Dubay C, Vignal A | title = A radiation hybrid map of 506 STS markers spanning human chromosome 11 | journal = Nature Genetics | volume = 8 | issue = 1 | pages = 70–6 | date = September 1994 | pmid = 7987395 | pmc =  | doi = 10.1038/ng0994-70 }}</ref><ref name="pmid12153988">{{cite journal | vauthors = Hohaus A, Person V, Behlke J, Schaper J, Morano I, Haase H | title = The carboxyl-terminal region of ahnak provides a link between cardiac L-type Ca2+ channels and the actin-based cytoskeleton | journal = FASEB Journal | volume = 16 | issue = 10 | pages = 1205–16 | date = August 2002 | pmid = 12153988 | pmc =  | doi = 10.1096/fj.01-0855com }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: AHNAK AHNAK nucleoprotein (desmoyokin)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79026| access-date = }}</ref> AHNAK was originally identified in 1989 (in [[Bovinae|bovine]] muzzle [[Epidermis (skin)|epidermal]] cells) and named desmoyokin due to its localization pattern (that resembled a [[yoke]]) in the [[Desmosome|desmosomal]] plaque.<ref name="pmid2677021">{{cite journal | vauthors = Hieda Y, Tsukita S, Tsukita S | title = A new high molecular mass protein showing unique localization in desmosomal plaque | journal = The Journal of Cell Biology | volume = 109 | issue = 4 Pt 1 | pages = 1511–8 | date = October 1989 | pmid = 2677021 | pmc = 2115823 | doi = 10.1083/jcb.109.4.1511 }}</ref> AHNAK has been shown to be essential for [[Pseudopodia|pseudopod]] protrusion and cell [[Cell migration|migration]].  
<ref name="pmid20388789">{{cite journal |vauthors=Shankar J, Messenberg A, Chan J, Underhill TM, Foster LJ, Nabi IR | title = Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells. | journal = Cancer Res. | volume = 70 | issue = 9 | pages = 3780–3790 |date=May 2010 | pmid = 20388789 | doi=10.1158/0008-5472.CAN-09-4439}}</ref>
<ref name="pmid20388789">{{cite journal | vauthors = Shankar J, Messenberg A, Chan J, Underhill TM, Foster LJ, Nabi IR | title = Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells | journal = Cancer Research | volume = 70 | issue = 9 | pages = 3780–90 | date = May 2010 | pmid = 20388789 | doi = 10.1158/0008-5472.CAN-09-4439 }}</ref>


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==Interactions==
== Interactions ==
AHNAK has been shown to [[Protein-protein interaction|interact]] with [[S100B]].<ref name=pmid11312263>{{cite journal |last=Gentil |first=B J |author2=Delphin C|author3=Mbele G O|author4=Deloulme J C|author5=Ferro M|author6=Garin J|author7= Baudier J |date=Jun 2001 |title=The giant protein AHNAK is a specific target for the calcium- and zinc-binding S100B protein: potential implications for Ca2+ homeostasis regulation by S100B |journal=J. Biol. Chem. |volume=276 |issue=26 |pages=23253–61 |publisher= |location = United States| issn = 0021-9258| pmid = 11312263 |doi = 10.1074/jbc.M010655200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>


==References==
AHNAK has been shown to [[Protein-protein interaction|interact]] with [[S100B]].<ref name=pmid11312263>{{cite journal | vauthors = Gentil BJ, Delphin C, Mbele GO, Deloulme JC, Ferro M, Garin J, Baudier J | title = The giant protein AHNAK is a specific target for the calcium- and zinc-binding S100B protein: potential implications for Ca2+ homeostasis regulation by S100B | journal = The Journal of Biological Chemistry | volume = 276 | issue = 26 | pages = 23253–61 | date = June 2001 | pmid = 11312263 | doi = 10.1074/jbc.M010655200 }}</ref>
 
== References ==
{{Reflist}}
{{Reflist}}


==External links==
== Further reading ==
* {{UCSC gene info|AHNAK}}
 
==Further reading==
{{Refbegin | 2}}
{{Refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Shtivelman E, Cohen FE, Bishop JM | title = A human gene (AHNAK) encoding an unusually large protein with a 1.2-microns polyionic rod structure | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 89 | issue = 12 | pages = 5472–6 | date = June 1992 | pmid = 1608957 | pmc = 49314 | doi = 10.1073/pnas.89.12.5472 }}
| citations =
* {{cite journal | vauthors = Kudoh J, Wang Y, Minoshima S, Hashimoto T, Amagai M, Nishikawa T, Shtivelman E, Bishop JM, Shimizu N | title = Localization of the human AHNAK/desmoyokin gene (AHNAK) to chromosome band 11q12 by somatic cell hybrid analysis and fluorescence in situ hybridization | journal = Cytogenetics and Cell Genetics | volume = 70 | issue = 3-4 | pages = 218–20 | year = 1995 | pmid = 7789175 | doi = 10.1159/000134037 }}
*{{cite journal | vauthors=Shtivelman E, Cohen FE, Bishop JM |title=A human gene (AHNAK) encoding an unusually large protein with a 1.2-microns polyionic rod structure. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 12 |pages= 5472–6 |year= 1992 |pmid= 1608957 |doi=10.1073/pnas.89.12.5472 | pmc=49314  }}
* {{cite journal | vauthors = Dias Neto E, Correa RG, Verjovski-Almeida S, Briones MR, Nagai MA, da Silva W, Zago MA, Bordin S, Costa FF, Goldman GH, Carvalho AF, Matsukuma A, Baia GS, Simpson DH, Brunstein A, de Oliveira PS, Bucher P, Jongeneel CV, O'Hare MJ, Soares F, Brentani RR, Reis LF, de Souza SJ, Simpson AJ | title = Shotgun sequencing of the human transcriptome with ORF expressed sequence tags | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 7 | pages = 3491–6 | date = March 2000 | pmid = 10737800 | pmc = 16267 | doi = 10.1073/pnas.97.7.3491 }}
*{{cite journal |vauthors=Kudoh J, Wang Y, Minoshima S |title=Localization of the human AHNAK/desmoyokin gene (AHNAK) to chromosome band 11q12 by somatic cell hybrid analysis and fluorescence in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=70 |issue= 3-4 |pages= 218–20 |year= 1995 |pmid= 7789175 |doi=10.1159/000134037 |display-authors=etal}}
* {{cite journal | vauthors = Gentil BJ, Delphin C, Mbele GO, Deloulme JC, Ferro M, Garin J, Baudier J | title = The giant protein AHNAK is a specific target for the calcium- and zinc-binding S100B protein: potential implications for Ca2+ homeostasis regulation by S100B | journal = The Journal of Biological Chemistry | volume = 276 | issue = 26 | pages = 23253–61 | date = June 2001 | pmid = 11312263 | doi = 10.1074/jbc.M010655200 }}
*{{cite journal |vauthors=Dias Neto E, Correa RG, Verjovski-Almeida S |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=10.1073/pnas.97.7.3491 | pmc=16267  |display-authors=etal}}
* {{cite journal | vauthors = Sussman J, Stokoe D, Ossina N, Shtivelman E | title = Protein kinase B phosphorylates AHNAK and regulates its subcellular localization | journal = The Journal of Cell Biology | volume = 154 | issue = 5 | pages = 1019–30 | date = September 2001 | pmid = 11535620 | pmc = 2196192 | doi = 10.1083/jcb.200105121 }}
*{{cite journal |vauthors=Gentil BJ, Delphin C, Mbele GO |title=The giant protein AHNAK is a specific target for the calcium- and zinc-binding S100B protein: potential implications for Ca2+ homeostasis regulation by S100B. |journal=J. Biol. Chem. |volume=276 |issue= 26 |pages= 23253–61 |year= 2001 |pmid= 11312263 |doi= 10.1074/jbc.M010655200 |display-authors=etal}}
* {{cite journal | vauthors = Wernyj RP, Ewing CM, Isaacs WB | title = Multiple antibodies to titin immunoreact with AHNAK and localize to the mitotic spindle machinery | journal = Cell Motility and the Cytoskeleton | volume = 50 | issue = 2 | pages = 101–13 | date = October 2001 | pmid = 11746675 | doi = 10.1002/cm.1044 }}
*{{cite journal |vauthors=Sussman J, Stokoe D, Ossina N, Shtivelman E |title=Protein kinase B phosphorylates AHNAK and regulates its subcellular localization. |journal=J. Cell Biol. |volume=154 |issue= 5 |pages= 1019–30 |year= 2001 |pmid= 11535620 |doi= 10.1083/jcb.200105121 | pmc=2196192 }}
* {{cite journal | vauthors = Straub BK, Boda J, Kuhn C, Schnoelzer M, Korf U, Kempf T, Spring H, Hatzfeld M, Franke WW | title = A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells | journal = Journal of Cell Science | volume = 116 | issue = Pt 24 | pages = 4985–95 | date = December 2003 | pmid = 14625392 | doi = 10.1242/jcs.00815 }}
*{{cite journal |vauthors=Wernyj RP, Ewing CM, Isaacs WB |title=Multiple antibodies to titin immunoreact with AHNAK and localize to the mitotic spindle machinery. |journal=Cell Motil. Cytoskeleton |volume=50 |issue= 2 |pages= 101–13 |year= 2004 |pmid= 11746675 |doi= 10.1002/cm.1044 }}
* {{cite journal | vauthors = Haase H, Pagel I, Khalina Y, Zacharzowsky U, Person V, Lutsch G, Petzhold D, Kott M, Schaper J, Morano I | title = The carboxyl-terminal ahnak domain induces actin bundling and stabilizes muscle contraction | journal = FASEB Journal | volume = 18 | issue = 7 | pages = 839–41 | date = May 2004 | pmid = 15001564 | doi = 10.1096/fj.03-0446fje }}
*{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
* {{cite journal | vauthors = Lee IH, You JO, Ha KS, Bae DS, Suh PG, Rhee SG, Bae YS | title = AHNAK-mediated activation of phospholipase C-gamma1 through protein kinase C | journal = The Journal of Biological Chemistry | volume = 279 | issue = 25 | pages = 26645–53 | date = June 2004 | pmid = 15033986 | doi = 10.1074/jbc.M311525200 }}
*{{cite journal  |vauthors=Straub BK, Boda J, Kuhn C |title=A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells. |journal=J. Cell Sci. |volume=116 |issue= Pt 24 |pages= 4985–95 |year= 2004 |pmid= 14625392 |doi= 10.1242/jcs.00815 |display-authors=etal}}
* {{cite journal | vauthors = Stiff T, Shtivelman E, Jeggo P, Kysela B | title = AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV-mediated double-stranded ligation | journal = DNA Repair | volume = 3 | issue = 3 | pages = 245–56 | date = March 2004 | pmid = 15177040 | doi = 10.1016/j.dnarep.2003.11.001 }}
*{{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
* {{cite journal | vauthors = Ahn J, Chung KS, Kim DU, Won M, Kim L, Kim KS, Nam M, Choi SJ, Kim HC, Yoon M, Chae SK, Hoe KL | title = Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus | journal = Journal of Biochemistry and Molecular Biology | volume = 37 | issue = 6 | pages = 741–8 | date = November 2004 | pmid = 15607035 | doi = 10.5483/bmbrep.2004.37.6.741 }}
*{{cite journal  |vauthors=Haase H, Pagel I, Khalina Y |title=The carboxyl-terminal ahnak domain induces actin bundling and stabilizes muscle contraction. |journal=FASEB J. |volume=18 |issue= 7 |pages= 839–41 |year= 2004 |pmid= 15001564 |doi= 10.1096/fj.03-0446fje |display-authors=etal}}
* {{cite journal | vauthors = Haase H, Alvarez J, Petzhold D, Doller A, Behlke J, Erdmann J, Hetzer R, Regitz-Zagrosek V, Vassort G, Morano I | title = Ahnak is critical for cardiac Ca(V)1.2 calcium channel function and its beta-adrenergic regulation | journal = FASEB Journal | volume = 19 | issue = 14 | pages = 1969–77 | date = December 2005 | pmid = 16319140 | doi = 10.1096/fj.05-3997com }}
*{{cite journal |vauthors=Lee IH, You JO, Ha KS |title=AHNAK-mediated activation of phospholipase C-gamma1 through protein kinase C. |journal=J. Biol. Chem. |volume=279 |issue= 25 |pages= 26645–53 |year= 2004 |pmid= 15033986 |doi= 10.1074/jbc.M311525200 |display-authors=etal}}
* {{cite journal | vauthors = Tompkins V, Hagen J, Zediak VP, Quelle DE | title = Identification of novel ARF binding proteins by two-hybrid screening | journal = Cell Cycle | volume = 5 | issue = 6 | pages = 641–6 | date = March 2006 | pmid = 16582619 | doi = 10.4161/cc.5.6.2560 }}
*{{cite journal |vauthors=Stiff T, Shtivelman E, Jeggo P, Kysela B |title=AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV-mediated double-stranded ligation. |journal=DNA Repair (Amst.) |volume=3 |issue= 3 |pages= 245–56 |year= 2004 |pmid= 15177040 |doi= 10.1016/j.dnarep.2003.11.001 }}
* {{cite journal | vauthors = De Seranno S, Benaud C, Assard N, Khediri S, Gerke V, Baudier J, Delphin C | title = Identification of an AHNAK binding motif specific for the Annexin2/S100A10 tetramer | journal = The Journal of Biological Chemistry | volume = 281 | issue = 46 | pages = 35030–8 | date = November 2006 | pmid = 16984913 | doi = 10.1074/jbc.M606545200 }}
*{{cite journal |vauthors=Ahn J, Chung KS, Kim DU |title=Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus. |journal=J. Biochem. Mol. Biol. |volume=37 |issue= 6 |pages= 741–8 |year= 2005 |pmid= 15607035 |doi= |display-authors=etal}}
*{{cite journal |vauthors=Haase H, Alvarez J, Petzhold D |title=Ahnak is critical for cardiac Ca(V)1.2 calcium channel function and its beta-adrenergic regulation. |journal=FASEB J. |volume=19 |issue= 14 |pages= 1969–77 |year= 2006 |pmid= 16319140 |doi= 10.1096/fj.05-3997com |display-authors=etal}}
*{{cite journal |vauthors=Tompkins V, Hagen J, Zediak VP, Quelle DE |title=Identification of novel ARF binding proteins by two-hybrid screening. |journal=Cell Cycle |volume=5 |issue= 6 |pages= 641–6 |year= 2006 |pmid= 16582619 |doi= 10.4161/cc.5.6.2560}}
*{{cite journal |vauthors=De Seranno S, Benaud C, Assard N |title=Identification of an AHNAK binding motif specific for the Annexin2/S100A10 tetramer. |journal=J. Biol. Chem. |volume=281 |issue= 46 |pages= 35030–8 |year= 2007 |pmid= 16984913 |doi= 10.1074/jbc.M606545200 |display-authors=etal}}
}}
{{Refend}}
{{Refend}}


<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
== External links ==
{{PBB_Controls
* {{UCSC gene info|AHNAK}}
| update_page = yes
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| update_protein_box = yes
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{{Gene-11-stub}}
{{Gene-11-stub}}

Latest revision as of 21:41, 17 March 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Neuroblast differentiation-associated protein AHNAK, also known as desmoyokin, is a protein that in humans is encoded by the AHNAK gene.[1][2][3] AHNAK was originally identified in 1989 (in bovine muzzle epidermal cells) and named desmoyokin due to its localization pattern (that resembled a yoke) in the desmosomal plaque.[4] AHNAK has been shown to be essential for pseudopod protrusion and cell migration. [5]


Interactions

AHNAK has been shown to interact with S100B.[6]

References

  1. ↑ James MR, Richard CW, Schott JJ, Yousry C, Clark K, Bell J, Terwilliger JD, Hazan J, Dubay C, Vignal A (September 1994). "A radiation hybrid map of 506 STS markers spanning human chromosome 11". Nature Genetics. 8 (1): 70–6. doi:10.1038/ng0994-70. PMID 7987395.
  2. ↑ Hohaus A, Person V, Behlke J, Schaper J, Morano I, Haase H (August 2002). "The carboxyl-terminal region of ahnak provides a link between cardiac L-type Ca2+ channels and the actin-based cytoskeleton". FASEB Journal. 16 (10): 1205–16. doi:10.1096/fj.01-0855com. PMID 12153988.
  3. ↑ "Entrez Gene: AHNAK AHNAK nucleoprotein (desmoyokin)".
  4. ↑ Hieda Y, Tsukita S, Tsukita S (October 1989). "A new high molecular mass protein showing unique localization in desmosomal plaque". The Journal of Cell Biology. 109 (4 Pt 1): 1511–8. doi:10.1083/jcb.109.4.1511. PMC 2115823. PMID 2677021.
  5. ↑ Shankar J, Messenberg A, Chan J, Underhill TM, Foster LJ, Nabi IR (May 2010). "Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells". Cancer Research. 70 (9): 3780–90. doi:10.1158/0008-5472.CAN-09-4439. PMID 20388789.
  6. ↑ Gentil BJ, Delphin C, Mbele GO, Deloulme JC, Ferro M, Garin J, Baudier J (June 2001). "The giant protein AHNAK is a specific target for the calcium- and zinc-binding S100B protein: potential implications for Ca2+ homeostasis regulation by S100B". The Journal of Biological Chemistry. 276 (26): 23253–61. doi:10.1074/jbc.M010655200. PMID 11312263.

Further reading

  • Shtivelman E, Cohen FE, Bishop JM (June 1992). "A human gene (AHNAK) encoding an unusually large protein with a 1.2-microns polyionic rod structure". Proceedings of the National Academy of Sciences of the United States of America. 89 (12): 5472–6. doi:10.1073/pnas.89.12.5472. PMC 49314. PMID 1608957.
  • Kudoh J, Wang Y, Minoshima S, Hashimoto T, Amagai M, Nishikawa T, Shtivelman E, Bishop JM, Shimizu N (1995). "Localization of the human AHNAK/desmoyokin gene (AHNAK) to chromosome band 11q12 by somatic cell hybrid analysis and fluorescence in situ hybridization". Cytogenetics and Cell Genetics. 70 (3–4): 218–20. doi:10.1159/000134037. PMID 7789175.
  • Dias Neto E, Correa RG, Verjovski-Almeida S, Briones MR, Nagai MA, da Silva W, Zago MA, Bordin S, Costa FF, Goldman GH, Carvalho AF, Matsukuma A, Baia GS, Simpson DH, Brunstein A, de Oliveira PS, Bucher P, Jongeneel CV, O'Hare MJ, Soares F, Brentani RR, Reis LF, de Souza SJ, Simpson AJ (March 2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proceedings of the National Academy of Sciences of the United States of America. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
  • Gentil BJ, Delphin C, Mbele GO, Deloulme JC, Ferro M, Garin J, Baudier J (June 2001). "The giant protein AHNAK is a specific target for the calcium- and zinc-binding S100B protein: potential implications for Ca2+ homeostasis regulation by S100B". The Journal of Biological Chemistry. 276 (26): 23253–61. doi:10.1074/jbc.M010655200. PMID 11312263.
  • Sussman J, Stokoe D, Ossina N, Shtivelman E (September 2001). "Protein kinase B phosphorylates AHNAK and regulates its subcellular localization". The Journal of Cell Biology. 154 (5): 1019–30. doi:10.1083/jcb.200105121. PMC 2196192. PMID 11535620.
  • Wernyj RP, Ewing CM, Isaacs WB (October 2001). "Multiple antibodies to titin immunoreact with AHNAK and localize to the mitotic spindle machinery". Cell Motility and the Cytoskeleton. 50 (2): 101–13. doi:10.1002/cm.1044. PMID 11746675.
  • Straub BK, Boda J, Kuhn C, Schnoelzer M, Korf U, Kempf T, Spring H, Hatzfeld M, Franke WW (December 2003). "A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells". Journal of Cell Science. 116 (Pt 24): 4985–95. doi:10.1242/jcs.00815. PMID 14625392.
  • Haase H, Pagel I, Khalina Y, Zacharzowsky U, Person V, Lutsch G, Petzhold D, Kott M, Schaper J, Morano I (May 2004). "The carboxyl-terminal ahnak domain induces actin bundling and stabilizes muscle contraction". FASEB Journal. 18 (7): 839–41. doi:10.1096/fj.03-0446fje. PMID 15001564.
  • Lee IH, You JO, Ha KS, Bae DS, Suh PG, Rhee SG, Bae YS (June 2004). "AHNAK-mediated activation of phospholipase C-gamma1 through protein kinase C". The Journal of Biological Chemistry. 279 (25): 26645–53. doi:10.1074/jbc.M311525200. PMID 15033986.
  • Stiff T, Shtivelman E, Jeggo P, Kysela B (March 2004). "AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV-mediated double-stranded ligation". DNA Repair. 3 (3): 245–56. doi:10.1016/j.dnarep.2003.11.001. PMID 15177040.
  • Ahn J, Chung KS, Kim DU, Won M, Kim L, Kim KS, Nam M, Choi SJ, Kim HC, Yoon M, Chae SK, Hoe KL (November 2004). "Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus". Journal of Biochemistry and Molecular Biology. 37 (6): 741–8. doi:10.5483/bmbrep.2004.37.6.741. PMID 15607035.
  • Haase H, Alvarez J, Petzhold D, Doller A, Behlke J, Erdmann J, Hetzer R, Regitz-Zagrosek V, Vassort G, Morano I (December 2005). "Ahnak is critical for cardiac Ca(V)1.2 calcium channel function and its beta-adrenergic regulation". FASEB Journal. 19 (14): 1969–77. doi:10.1096/fj.05-3997com. PMID 16319140.
  • Tompkins V, Hagen J, Zediak VP, Quelle DE (March 2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle. 5 (6): 641–6. doi:10.4161/cc.5.6.2560. PMID 16582619.
  • De Seranno S, Benaud C, Assard N, Khediri S, Gerke V, Baudier J, Delphin C (November 2006). "Identification of an AHNAK binding motif specific for the Annexin2/S100A10 tetramer". The Journal of Biological Chemistry. 281 (46): 35030–8. doi:10.1074/jbc.M606545200. PMID 16984913.

External links


Retrieved from "https://www.wikidoc.org/index.php?title=AHNAK&oldid=1527862"