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*{{cite journal |vauthors=Jankowski SA, De Jong P, Meltzer PS |title=Genomic structure of SAS, a member of the transmembrane 4 superfamily amplified in human sarcomas |journal=Genomics |volume=25 |issue= 2 |pages= 501–6 |year= 1995 |pmid= 7789984 |doi=10.1016/0888-7543(95)80051-M }} | *{{cite journal |vauthors=Jankowski SA, De Jong P, Meltzer PS |title=Genomic structure of SAS, a member of the transmembrane 4 superfamily amplified in human sarcomas |journal=Genomics |volume=25 |issue= 2 |pages= 501–6 |year= 1995 |pmid= 7789984 |doi=10.1016/0888-7543(95)80051-M }} | ||
*{{cite journal | author=Jankowski SA |title=SAS, a gene amplified in human sarcomas, encodes a new member of the transmembrane 4 superfamily of proteins |journal=Oncogene |volume=9 |issue= 4 |pages= 1205–11 |year= 1994 |pmid= 8134123 |doi= |name-list-format=vanc| author2=Mitchell DS | author3=Smith SH | display-authors=3 | last4=Trent | first4=JM | last5=Meltzer | first5=PS }} | *{{cite journal | author=Jankowski SA |title=SAS, a gene amplified in human sarcomas, encodes a new member of the transmembrane 4 superfamily of proteins |journal=Oncogene |volume=9 |issue= 4 |pages= 1205–11 |year= 1994 |pmid= 8134123 |doi= |name-list-format=vanc| author2=Mitchell DS | author3=Smith SH | display-authors=3 | last4=Trent | first4=JM | last5=Meltzer | first5=PS }} | ||
*{{cite journal | author=Elkahloun AG |title=Transcript mapping in a 46-kb sequenced region at the core of 12q13.3 amplification in human cancers |journal=Genomics |volume=42 |issue= 2 |pages= 295–301 |year= 1997 |pmid= 9192850 |doi= 10.1006/geno.1997.4727 |name-list-format=vanc| author2=Krizman DB | author3=Wang Z | display-authors=3 | last4=Hofmann | first4=Tiffany A. | last5=Roe | first5=Bruce | last6=Meltzer | first6=Paul S. }} | *{{cite journal | author=Elkahloun AG |title=Transcript mapping in a 46-kb sequenced region at the core of 12q13.3 amplification in human cancers |journal=Genomics |volume=42 |issue= 2 |pages= 295–301 |year= 1997 |pmid= 9192850 |doi= 10.1006/geno.1997.4727 |name-list-format=vanc| author2=Krizman DB | author3=Wang Z | display-authors=3 | last4=Hofmann | first4=Tiffany A. | last5=Roe | first5=Bruce | last6=Meltzer | first6=Paul S. |url=https://zenodo.org/record/1229731/files/article.pdf}} | ||
*{{cite journal | author=Wunder JS |title=Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas |journal=Oncogene |volume=18 |issue= 3 |pages= 783–8 |year= 1999 |pmid= 9989829 |doi= 10.1038/sj.onc.1202346 |name-list-format=vanc| author2=Eppert K | author3=Burrow SR | display-authors=3 | last4=Gogkoz | first4=Nalan | last5=Bell | first5=Robert S | last6=Andrulis | first6=Irene L }} | *{{cite journal | author=Wunder JS |title=Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas |journal=Oncogene |volume=18 |issue= 3 |pages= 783–8 |year= 1999 |pmid= 9989829 |doi= 10.1038/sj.onc.1202346 |name-list-format=vanc| author2=Eppert K | author3=Burrow SR | display-authors=3 | last4=Gogkoz | first4=Nalan | last5=Bell | first5=Robert S | last6=Andrulis | first6=Irene L }} | ||
*{{cite journal | author=Ragazzini P |title=Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma |journal=Cancer Detect. Prev. |volume=23 |issue= 2 |pages= 129–36 |year= 1999 |pmid= 10101594 |doi=10.1046/j.1525-1500.1999.09907.x |name-list-format=vanc| author2=Gamberi G | author3=Benassi MS | display-authors=3 | last4=Orlando | last5=Sestini | last6=Ferrari | last7=Molendini | last8=Sollazzo | last9=Merli | first4=C | first5=R | first6=C | first7=L | first8=MR | first9=M }} | *{{cite journal | author=Ragazzini P |title=Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma |journal=Cancer Detect. Prev. |volume=23 |issue= 2 |pages= 129–36 |year= 1999 |pmid= 10101594 |doi=10.1046/j.1525-1500.1999.09907.x |name-list-format=vanc| author2=Gamberi G | author3=Benassi MS | display-authors=3 | last4=Orlando | last5=Sestini | last6=Ferrari | last7=Molendini | last8=Sollazzo | last9=Merli | first4=C | first5=R | first6=C | first7=L | first8=MR | first9=M }} | ||
*{{cite journal | author=Suzuki Y |title=Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes |journal=Genome Res. |volume=11 |issue= 5 |pages= 677–84 |year= 2001 |pmid= 11337467 |doi= 10.1101/gr. | *{{cite journal | author=Suzuki Y |title=Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes |journal=Genome Res. |volume=11 |issue= 5 |pages= 677–84 |year= 2001 |pmid= 11337467 |doi= 10.1101/gr.gr-1640r| pmc=311086 |name-list-format=vanc| author2=Tsunoda T | author3=Sese J | display-authors=3 | last4=Taira | first4=H | last5=Mizushima-Sugano | first5=J | last6=Hata | first6=H | last7=Ota | first7=T | last8=Isogai | first8=T | last9=Tanaka | first9=T }} | ||
*{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} | *{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} | ||
*{{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }} | *{{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }} | ||
Latest revision as of 17:05, 5 November 2018
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Tetraspanin-31 is a protein that in humans is encoded by the TSPAN31 gene.[1]
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma.[1]
References
Further reading
- Wright MD, Tomlinson MG (1995). "The ins and outs of the transmembrane 4 superfamily". Immunol. Today. 15 (12): 588–94. doi:10.1016/0167-5699(94)90222-4. PMID 7531445.
- Meltzer PS, Jankowski SA, Dal Cin P, et al. (1992). "Identification and cloning of a novel amplified DNA sequence in human malignant fibrous histiocytoma derived from a region of chromosome 12 frequently rearranged in soft tissue tumors". Cell Growth Differ. 2 (10): 495–501. PMID 1661131.
- Jankowski SA, De Jong P, Meltzer PS (1995). "Genomic structure of SAS, a member of the transmembrane 4 superfamily amplified in human sarcomas". Genomics. 25 (2): 501–6. doi:10.1016/0888-7543(95)80051-M. PMID 7789984.
- Jankowski SA, Mitchell DS, Smith SH, et al. (1994). "SAS, a gene amplified in human sarcomas, encodes a new member of the transmembrane 4 superfamily of proteins". Oncogene. 9 (4): 1205–11. PMID 8134123.
- Elkahloun AG, Krizman DB, Wang Z, et al. (1997). "Transcript mapping in a 46-kb sequenced region at the core of 12q13.3 amplification in human cancers" (PDF). Genomics. 42 (2): 295–301. doi:10.1006/geno.1997.4727. PMID 9192850.
- Wunder JS, Eppert K, Burrow SR, et al. (1999). "Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas". Oncogene. 18 (3): 783–8. doi:10.1038/sj.onc.1202346. PMID 9989829.
- Ragazzini P, Gamberi G, Benassi MS, et al. (1999). "Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma". Cancer Detect. Prev. 23 (2): 129–36. doi:10.1046/j.1525-1500.1999.09907.x. PMID 10101594.
- Suzuki Y, Tsunoda T, Sese J, et al. (2001). "Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes". Genome Res. 11 (5): 677–84. doi:10.1101/gr.gr-1640r. PMC 311086. PMID 11337467.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Ragazzini P, Gamberi G, Pazzaglia L, et al. (2004). "Amplification of CDK4, MDM2, SAS and GLI genes in leiomyosarcoma, alveolar and embryonal rhabdomyosarcoma". Histol. Histopathol. 19 (2): 401–11. PMID 15024701.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
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