B4GALNT2: Difference between revisions
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'''Beta-1,4 N-acetylgalactosaminyltransferase 2''' is an [[enzyme]] that in humans is encoded by the ''B4GALNT2'' [[gene]].<ref name="pmid8782649">{{cite journal | vauthors = Dohi T, Yuyama Y, Natori Y, Smith PL, Lowe JB, Oshima M | title = Detection of N-acetylgalactosaminyltransferase mRNA which determines expression of Sda blood group carbohydrate structure in human gastrointestinal mucosa and cancer | journal = International Journal of Cancer | volume = 67 | issue = 5 | pages = 626–31 | date = Sep 1996 | pmid = 8782649 | pmc = | doi = 10.1002/(SICI)1097-0215(19960904)67:5<626::AID-IJC6>3.0.CO;2-W }}</ref><ref name="pmid12678917">{{cite journal | vauthors = Montiel MD, Krzewinski-Recchi MA, Delannoy P, Harduin-Lepers A | title = Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain | journal = The Biochemical Journal | volume = 373 | issue = Pt 2 | pages = 369–79 | date = Jul 2003 | pmid = 12678917 | pmc = 1223490 | doi = 10.1042/BJ20021892 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=124872| accessdate = }}</ref> | '''Beta-1,4 N-acetylgalactosaminyltransferase 2''' is an [[enzyme]] that in humans is encoded by the ''B4GALNT2'' [[gene]].<ref name="pmid8782649">{{cite journal | vauthors = Dohi T, Yuyama Y, Natori Y, Smith PL, Lowe JB, Oshima M | title = Detection of N-acetylgalactosaminyltransferase mRNA which determines expression of Sda blood group carbohydrate structure in human gastrointestinal mucosa and cancer | journal = International Journal of Cancer | volume = 67 | issue = 5 | pages = 626–31 | date = Sep 1996 | pmid = 8782649 | pmc = | doi = 10.1002/(SICI)1097-0215(19960904)67:5<626::AID-IJC6>3.0.CO;2-W }}</ref><ref name="pmid12678917">{{cite journal | vauthors = Montiel MD, Krzewinski-Recchi MA, Delannoy P, Harduin-Lepers A | title = Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain | journal = The Biochemical Journal | volume = 373 | issue = Pt 2 | pages = 369–79 | date = Jul 2003 | pmid = 12678917 | pmc = 1223490 | doi = 10.1042/BJ20021892 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=124872| accessdate = }}</ref> |
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Beta-1,4 N-acetylgalactosaminyltransferase 2 is an enzyme that in humans is encoded by the B4GALNT2 gene.[1][2][3]
References
- ↑ Dohi T, Yuyama Y, Natori Y, Smith PL, Lowe JB, Oshima M (Sep 1996). "Detection of N-acetylgalactosaminyltransferase mRNA which determines expression of Sda blood group carbohydrate structure in human gastrointestinal mucosa and cancer". International Journal of Cancer. 67 (5): 626–31. doi:10.1002/(SICI)1097-0215(19960904)67:5<626::AID-IJC6>3.0.CO;2-W. PMID 8782649.
- ↑ Montiel MD, Krzewinski-Recchi MA, Delannoy P, Harduin-Lepers A (Jul 2003). "Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain". The Biochemical Journal. 373 (Pt 2): 369–79. doi:10.1042/BJ20021892. PMC 1223490. PMID 12678917.
- ↑ "Entrez Gene: B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2".
External links
- Human B4GALNT2 genome location and B4GALNT2 gene details page in the UCSC Genome Browser.
Further reading
- Berger EG (Feb 2002). "Ectopic localizations of Golgi glycosyltransferases". Glycobiology. 12 (2): 29R–36R. doi:10.1093/glycob/12.2.29R. PMID 11886838.
- Wang HR, Hsieh CY, Twu YC, Yu LC (Jan 2008). "Expression of the human Sd(a) beta-1,4-N-acetylgalactosaminyltransferase II gene is dependent on the promoter methylation status". Glycobiology. 18 (1): 104–13. doi:10.1093/glycob/cwm120. PMID 17965433.
- Kawamura YI, Kawashima R, Fukunaga R, Hirai K, Toyama-Sorimachi N, Tokuhara M, Shimizu T, Dohi T (Jul 2005). "Introduction of Sd(a) carbohydrate antigen in gastrointestinal cancer cells eliminates selectin ligands and inhibits metastasis". Cancer Research. 65 (14): 6220–7. doi:10.1158/0008-5472.CAN-05-0639. PMID 16024623.
- Lo Presti L, Cabuy E, Chiricolo M, Dall'Olio F (Nov 2003). "Molecular cloning of the human beta1,4 N-acetylgalactosaminyltransferase responsible for the biosynthesis of the Sd(a) histo-blood group antigen: the sequence predicts a very long cytoplasmic domain". Journal of Biochemistry. 134 (5): 675–82. doi:10.1093/jb/mvg192. PMID 14688233.
- Piller F, Blanchard D, Huet M, Cartron JP (Jun 1986). "Identification of a alpha-NeuAc-(2----3)-beta-D-galactopyranosyl N-acetyl-beta-D-galactosaminyltransferase in human kidney". Carbohydrate Research. 149 (1): 171–84. doi:10.1016/S0008-6215(00)90376-8. PMID 2425965.
- Li PT, Liao CJ, Wu WG, Yu LC, Chu ST (Jun 2011). "Progesterone-regulated B4galnt2 expression is a requirement for embryo implantation in mice". Fertility and Sterility. 95 (7): 2404–9, 2409.e1–3. doi:10.1016/j.fertnstert.2011.03.043. PMID 21481371.
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