FUT6: Difference between revisions

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*{{cite journal  |vauthors=Weston BW, Smith PL, Kelly RJ, Lowe JB |title=Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. |journal=J. Biol. Chem. |volume=267 |issue= 34 |pages= 24575–84 |year= 1992 |pmid= 1339443 |doi=  }}
*{{cite journal  |vauthors=Weston BW, Smith PL, Kelly RJ, Lowe JB |title=Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. |journal=J. Biol. Chem. |volume=267 |issue= 34 |pages= 24575–84 |year= 1992 |pmid= 1339443 |doi=  }}
*{{cite journal  |vauthors=Cameron HS, Szczepaniak D, Weston BW |title=Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms. |journal=J. Biol. Chem. |volume=270 |issue= 34 |pages= 20112–22 |year= 1995 |pmid= 7650030 |doi=10.1074/jbc.270.34.20112  }}
*{{cite journal  |vauthors=Cameron HS, Szczepaniak D, Weston BW |title=Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms. |journal=J. Biol. Chem. |volume=270 |issue= 34 |pages= 20112–22 |year= 1995 |pmid= 7650030 |doi=10.1074/jbc.270.34.20112  }}
*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
*{{cite journal  |vauthors=Mollicone R, Reguigne I, Fletcher A |title=Molecular basis for plasma alpha(1,3)-fucosyltransferase gene deficiency (FUT6). |journal=J. Biol. Chem. |volume=269 |issue= 17 |pages= 12662–71 |year= 1994 |pmid= 8175676 |doi=  |display-authors=etal}}
*{{cite journal  |vauthors=Mollicone R, Reguigne I, Fletcher A |title=Molecular basis for plasma alpha(1,3)-fucosyltransferase gene deficiency (FUT6). |journal=J. Biol. Chem. |volume=269 |issue= 17 |pages= 12662–71 |year= 1994 |pmid= 8175676 |doi=  |display-authors=etal}}
*{{cite journal  |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  |display-authors=etal}}
*{{cite journal  |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  |display-authors=etal}}
*{{cite journal  |vauthors=Borsig L, Imbach T, Höchli M, Berger EG |title=alpha1,3Fucosyltransferase VI is expressed in HepG2 cells and codistributed with beta1,4galactosyltransferase I in the golgi apparatus and monensin-induced swollen vesicles. |journal=Glycobiology |volume=9 |issue= 11 |pages= 1273–80 |year= 2000 |pmid= 10536043 |doi=10.1093/glycob/9.11.1273  }}
*{{cite journal  |vauthors=Borsig L, Imbach T, Höchli M, Berger EG |title=alpha1,3Fucosyltransferase VI is expressed in HepG2 cells and codistributed with beta1,4galactosyltransferase I in the golgi apparatus and monensin-induced swollen vesicles. |journal=Glycobiology |volume=9 |issue= 11 |pages= 1273–80 |year= 2000 |pmid= 10536043 |doi=10.1093/glycob/9.11.1273  }}
*{{cite journal  |vauthors=Schnyder-Candrian S, Borsig L, Moser R, Berger EG |title=Localization of alpha 1,3-fucosyltransferase VI in Weibel-Palade bodies of human endothelial cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 15 |pages= 8369–74 |year= 2000 |pmid= 10900002 |doi=10.1073/pnas.97.15.8369  | pmc=26954  }}
*{{cite journal  |vauthors=Schnyder-Candrian S, Borsig L, Moser R, Berger EG |title=Localization of alpha 1,3-fucosyltransferase VI in Weibel-Palade bodies of human endothelial cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 15 |pages= 8369–74 |year= 2000 |pmid= 10900002 |doi=10.1073/pnas.97.15.8369  | pmc=26954  }}

Latest revision as of 13:19, 7 November 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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n/a

RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT6 gene.[1][2][3]

The alpha-1,3-fucosyltransferases constitute a large family of glycosyltransferases with a high degree of homology. The enzymes of this family comprise 3 main activity patterns called myeloid, plasma, and Lewis, based on their capacity to transfer alpha-L-fucose to distinct oligosaccharide acceptors, their sensitivity to N-ethylmaleimide inhibition, their cation requirements, and their tissue-specific expression patterns. The different categories of alpha-1,3-fucosyltransferases are sequentially expressed during embryo-fetal development.[supplied by OMIM][3]

References

  1. Koszdin KL, Bowen BR (Oct 1992). "The cloning and expression of a human alpha-1,3 fucosyltransferase capable of forming the E-selectin ligand". Biochem Biophys Res Commun. 187 (1): 152–7. doi:10.1016/S0006-291X(05)81472-X. PMID 1520296.
  2. McCurley RS, Recinos A III, Olsen AS, Gingrich JC, Szczepaniak D, Cameron HS, Krauss R, Weston BW (Jul 1995). "Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21". Genomics. 26 (1): 142–6. doi:10.1016/0888-7543(95)80094-3. PMID 7782074.
  3. 3.0 3.1 "Entrez Gene: FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)".

Further reading