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{{Infobox_gene}}
{{Infobox_gene}}
'''SHC-transforming protein 2''' is a [[protein]] that in humans is encoded by the ''SHC2'' [[gene]].<ref name="pmid7527937">{{cite journal |author1=Kavanaugh WM |author2=Williams LT | title = An alternative to SH2 domains for binding tyrosine-phosphorylated proteins | journal = Science | volume = 266 | issue = 5192 | pages = 1862–5 |date=Jan 1995 | pmid = 7527937 | pmc =  | doi =10.1126/science.7527937  }}</ref><ref name="pmid9507002">{{cite journal |author1=Nakamura T |author2=Muraoka S |author3=Sanokawa R |author4=Mori N | title = N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling | journal = J Biol Chem | volume = 273 | issue = 12 | pages = 6960–7 |date=Apr 1998 | pmid = 9507002 | pmc =  | doi =10.1074/jbc.273.12.6960  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SHC2 SHC (Src homology 2 domain containing) transforming protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25759| accessdate = }}</ref>
'''SHC-transforming protein 2''' is a [[protein]] that in humans is encoded by the ''SHC2'' [[gene]].<ref name="pmid7527937">{{cite journal |author1=Kavanaugh WM |author2=Williams LT | title = An alternative to SH2 domains for binding tyrosine-phosphorylated proteins | journal = Science | volume = 266 | issue = 5192 | pages = 1862–5 |date=Jan 1995 | pmid = 7527937 | pmc =  | doi =10.1126/science.7527937  |bibcode=1994Sci...266.1862K }}</ref><ref name="pmid9507002">{{cite journal |author1=Nakamura T |author2=Muraoka S |author3=Sanokawa R |author4=Mori N | title = N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling | journal = J Biol Chem | volume = 273 | issue = 12 | pages = 6960–7 |date=Apr 1998 | pmid = 9507002 | pmc =  | doi =10.1074/jbc.273.12.6960  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SHC2 SHC (Src homology 2 domain containing) transforming protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25759| accessdate = }}</ref>


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| citations =
| citations =
*{{cite journal  |vauthors=Choy KW, Wang CC, Ogura A, etal |title=Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes. |journal=Physiol. Genomics |volume=25 |issue= 1 |pages= 9–15 |year= 2007 |pmid= 16368877 |doi= 10.1152/physiolgenomics.00121.2005 }}
*{{cite journal  |vauthors=Choy KW, Wang CC, Ogura A, etal |title=Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes. |journal=Physiol. Genomics |volume=25 |issue= 1 |pages= 9–15 |year= 2007 |pmid= 16368877 |doi= 10.1152/physiolgenomics.00121.2005 }}
*{{cite journal  |vauthors=Grimwood J, Gordon LA, Olsen A, etal |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 }}
*{{cite journal  |vauthors=Grimwood J, Gordon LA, Olsen A, etal |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 |bibcode=2004Natur.428..529G }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M }}
*{{cite journal  |author1=Liu HY |author2=Meakin SO |title=ShcB and ShcC activation by the Trk family of receptor tyrosine kinases. |journal=J. Biol. Chem. |volume=277 |issue= 29 |pages= 26046–56 |year= 2002 |pmid= 12006576 |doi= 10.1074/jbc.M111659200 }}
*{{cite journal  |author1=Liu HY |author2=Meakin SO |title=ShcB and ShcC activation by the Trk family of receptor tyrosine kinases. |journal=J. Biol. Chem. |volume=277 |issue= 29 |pages= 26046–56 |year= 2002 |pmid= 12006576 |doi= 10.1074/jbc.M111659200 }}
*{{cite journal  |vauthors=Warner AJ, Lopez-Dee J, Knight EL, etal |title=The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells. |journal=Biochem. J. |volume=347 |issue= Pt 2 |pages= 501–9 |year= 2001 |pmid= 10749680 |doi=  10.1042/0264-6021:3470501| pmc=1220983  }}
*{{cite journal  |vauthors=Warner AJ, Lopez-Dee J, Knight EL, etal |title=The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells. |journal=Biochem. J. |volume=347 |issue= Pt 2 |pages= 501–9 |year= 2001 |pmid= 10749680 |doi=  10.1042/0264-6021:3470501| pmc=1220983  }}

Latest revision as of 04:34, 26 June 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

SHC-transforming protein 2 is a protein that in humans is encoded by the SHC2 gene.[1][2][3]


Interactions

SHC2 has been shown to interact with Kinase insert domain receptor.[4]

References

  1. ↑ Kavanaugh WM; Williams LT (Jan 1995). "An alternative to SH2 domains for binding tyrosine-phosphorylated proteins". Science. 266 (5192): 1862–5. Bibcode:1994Sci...266.1862K. doi:10.1126/science.7527937. PMID 7527937.
  2. ↑ Nakamura T; Muraoka S; Sanokawa R; Mori N (Apr 1998). "N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling". J Biol Chem. 273 (12): 6960–7. doi:10.1074/jbc.273.12.6960. PMID 9507002.
  3. ↑ "Entrez Gene: SHC2 SHC (Src homology 2 domain containing) transforming protein 2".
  4. ↑ Warner, A J; Lopez-Dee J; Knight E L; Feramisco J R; Prigent S A (Apr 2000). "The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells". Biochem. J. England. 347 (Pt 2): 501–9. doi:10.1042/0264-6021:3470501. ISSN 0264-6021. PMC 1220983. PMID 10749680.

Further reading



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