MARCH2: Difference between revisions
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'''E3 ubiquitin-protein ligase MARCH2''' is an [[enzyme]] that in humans is encoded by the ''MARCH2'' [[gene]].<ref name="pmid11042152">{{cite journal |vauthors=Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z | title = Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells | journal = Genome | '''E3 ubiquitin-protein ligase MARCH2''' is an [[enzyme]] that in humans is encoded by the ''MARCH2'' [[gene]].<ref name="pmid11042152">{{cite journal | vauthors = Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z | title = Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells | journal = Genome Research | volume = 10 | issue = 10 | pages = 1546–60 | date = October 2000 | pmid = 11042152 | pmc = 310934 | doi = 10.1101/gr.140200 }}</ref><ref name="pmid14722266">{{cite journal | vauthors = Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Früh K | title = Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins | journal = Journal of Virology | volume = 78 | issue = 3 | pages = 1109–20 | date = February 2004 | pmid = 14722266 | pmc = 321412 | doi = 10.1128/JVI.78.3.1109-1120.2004 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MARCH2 membrane-associated ring finger (C3HC4) 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51257| access-date = }}</ref> It is a member of the MARCH family of E3 ligases, and plays an important role in the [[Protein turnover|turnover]] of [[membrane proteins]].<ref name="Zhang_2018">{{cite journal | vauthors = Zhang Y, Lu J, Liu X | title = MARCH2 is upregulated in HIV-1 infection and inhibits HIV-1 production through envelope protein translocation or degradation | journal = Virology | volume = 518 | issue = | pages = 293–300 | date = May 2018 | pmid = 29573664 | doi = 10.1016/j.virol.2018.02.003 }}</ref> | ||
== References == | |||
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== Further reading == | |||
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* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = April 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }} | |||
==Further reading== | * {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = April 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }} | ||
{{refbegin | | * {{cite journal | vauthors = Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW | title = Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation | journal = Nature Biotechnology | volume = 22 | issue = 6 | pages = 707–16 | date = June 2004 | pmid = 15146197 | doi = 10.1038/nbt971 }} | ||
* {{cite journal | vauthors = Nakamura N, Fukuda H, Kato A, Hirose S | title = MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking | journal = Molecular Biology of the Cell | volume = 16 | issue = 4 | pages = 1696–710 | date = April 2005 | pmid = 15689499 | pmc = 1073653 | doi = 10.1091/mbc.E04-03-0216 }} | |||
* {{cite journal | vauthors = Fukuda H, Nakamura N, Hirose S | title = MARCH-III Is a novel component of endosomes with properties similar to those of MARCH-II | journal = Journal of Biochemistry | volume = 139 | issue = 1 | pages = 137–45 | date = January 2006 | pmid = 16428329 | doi = 10.1093/jb/mvj012 }} | |||
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{{gene-19-stub}} | {{gene-19-stub}} |
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E3 ubiquitin-protein ligase MARCH2 is an enzyme that in humans is encoded by the MARCH2 gene.[1][2][3] It is a member of the MARCH family of E3 ligases, and plays an important role in the turnover of membrane proteins.[4]
References
- ↑ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (October 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Research. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
- ↑ Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Früh K (February 2004). "Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins". Journal of Virology. 78 (3): 1109–20. doi:10.1128/JVI.78.3.1109-1120.2004. PMC 321412. PMID 14722266.
- ↑ "Entrez Gene: MARCH2 membrane-associated ring finger (C3HC4) 2".
- ↑ Zhang Y, Lu J, Liu X (May 2018). "MARCH2 is upregulated in HIV-1 infection and inhibits HIV-1 production through envelope protein translocation or degradation". Virology. 518: 293–300. doi:10.1016/j.virol.2018.02.003. PMID 29573664.
Further reading
- Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (April 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
- Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (April 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
- Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW (June 2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature Biotechnology. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Nakamura N, Fukuda H, Kato A, Hirose S (April 2005). "MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking". Molecular Biology of the Cell. 16 (4): 1696–710. doi:10.1091/mbc.E04-03-0216. PMC 1073653. PMID 15689499.
- Fukuda H, Nakamura N, Hirose S (January 2006). "MARCH-III Is a novel component of endosomes with properties similar to those of MARCH-II". Journal of Biochemistry. 139 (1): 137–45. doi:10.1093/jb/mvj012. PMID 16428329.
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