TNPO2: Difference between revisions
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'''Transportin-2''' is a [[protein]] that in humans is encoded by the ''TNPO2'' [[gene]].<ref name="pmid9298975">{{cite journal |vauthors=Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G | title = Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins | journal = J Cell Biol | volume = 138 | issue = 6 | pages = 1181–92 |date=October 1997 | pmid = 9298975 | pmc = 2132560 | doi =10.1083/jcb.138.6.1181 }}</ref><ref name="pmid12384575">{{cite journal |vauthors=Shamsher MK, Ploski J, Radu A | title = Karyopherin beta 2B participates in mRNA export from the nucleus | journal = Proc Natl Acad Sci U S A | volume = 99 | issue = 22 | pages = 14195–9 |date=October 2002 | pmid = 12384575 | pmc = 137860 | doi = 10.1073/pnas.212518199 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=30000| accessdate = }}</ref> | '''Transportin-2''' is a [[protein]] that in humans is encoded by the ''TNPO2'' [[gene]].<ref name="pmid9298975">{{cite journal |vauthors=Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G | title = Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins | journal = J Cell Biol | volume = 138 | issue = 6 | pages = 1181–92 |date=October 1997 | pmid = 9298975 | pmc = 2132560 | doi =10.1083/jcb.138.6.1181 }}</ref><ref name="pmid12384575">{{cite journal |vauthors=Shamsher MK, Ploski J, Radu A | title = Karyopherin beta 2B participates in mRNA export from the nucleus | journal = Proc Natl Acad Sci U S A | volume = 99 | issue = 22 | pages = 14195–9 |date=October 2002 | pmid = 12384575 | pmc = 137860 | doi = 10.1073/pnas.212518199 | bibcode = 2002PNAS...9914195S }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=30000| accessdate = }}</ref> | ||
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*{{cite journal |vauthors=Gallouzi IE, Steitz JA |title=Delineation of mRNA export pathways by the use of cell-permeable peptides. |journal=Science |volume=294 |issue= 5548 |pages= 1895–901 |year= 2001 |pmid= 11729309 |doi= 10.1126/science.1064693 }} | *{{cite journal |vauthors=Gallouzi IE, Steitz JA |title=Delineation of mRNA export pathways by the use of cell-permeable peptides. |journal=Science |volume=294 |issue= 5548 |pages= 1895–901 |year= 2001 |pmid= 11729309 |doi= 10.1126/science.1064693 |bibcode=2001Sci...294.1895G }} | ||
*{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }} | *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }} | ||
*{{cite journal |vauthors=Blanc V, Kennedy S, Davidson NO |title=A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling. |journal=J. Biol. Chem. |volume=278 |issue= 42 |pages= 41198–204 |year= 2003 |pmid= 12896982 |doi= 10.1074/jbc.M302951200 }} | *{{cite journal |vauthors=Blanc V, Kennedy S, Davidson NO |title=A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling. |journal=J. Biol. Chem. |volume=278 |issue= 42 |pages= 41198–204 |year= 2003 |pmid= 12896982 |doi= 10.1074/jbc.M302951200 }} | ||
*{{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }} | *{{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }} | ||
*{{cite journal |vauthors=Güttinger S, Mühlhäusser P, Koller-Eichhorn R, etal |title=Transportin2 functions as importin and mediates nuclear import of HuR. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 9 |pages= 2918–23 |year= 2004 |pmid= 14981248 |doi= 10.1073/pnas.0400342101 | pmc=365720 }} | *{{cite journal |vauthors=Güttinger S, Mühlhäusser P, Koller-Eichhorn R, etal |title=Transportin2 functions as importin and mediates nuclear import of HuR. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 9 |pages= 2918–23 |year= 2004 |pmid= 14981248 |doi= 10.1073/pnas.0400342101 | pmc=365720 |bibcode=2004PNAS..101.2918G }} | ||
*{{cite journal |vauthors=Rebane A, Aab A, Steitz JA |title=Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR. |journal=RNA |volume=10 |issue= 4 |pages= 590–9 |year= 2004 |pmid= 15037768 |doi=10.1261/rna.5224304 | pmc=1370549 }} | *{{cite journal |vauthors=Rebane A, Aab A, Steitz JA |title=Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR. |journal=RNA |volume=10 |issue= 4 |pages= 590–9 |year= 2004 |pmid= 15037768 |doi=10.1261/rna.5224304 | pmc=1370549 }} | ||
*{{cite journal |vauthors=Lee BJ, Cansizoglu AE, Süel KE, etal |title=Rules for nuclear localization sequence recognition by karyopherin beta 2. |journal=Cell |volume=126 |issue= 3 |pages= 543–58 |year= 2006 |pmid= 16901787 |doi= 10.1016/j.cell.2006.05.049 |pmc=3442361}} | *{{cite journal |vauthors=Lee BJ, Cansizoglu AE, Süel KE, etal |title=Rules for nuclear localization sequence recognition by karyopherin beta 2. |journal=Cell |volume=126 |issue= 3 |pages= 543–58 |year= 2006 |pmid= 16901787 |doi= 10.1016/j.cell.2006.05.049 |pmc=3442361}} | ||
Latest revision as of 19:14, 26 June 2018
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Transportin-2 is a protein that in humans is encoded by the TNPO2 gene.[1][2][3]
Interactions
TNPO2 has been shown to interact with NXF1,[2] NUP98[4] and Ran (biology).[2]
References
- ↑ Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G (October 1997). "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins". J Cell Biol. 138 (6): 1181–92. doi:10.1083/jcb.138.6.1181. PMC 2132560. PMID 9298975.
- ↑ 2.0 2.1 2.2 Shamsher MK, Ploski J, Radu A (October 2002). "Karyopherin beta 2B participates in mRNA export from the nucleus". Proc Natl Acad Sci U S A. 99 (22): 14195–9. Bibcode:2002PNAS...9914195S. doi:10.1073/pnas.212518199. PMC 137860. PMID 12384575.
- ↑ "Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)".
- ↑ Fontoura, B M; Blobel G; Yaseen N R (October 2000). "The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import". J. Biol. Chem. UNITED STATES. 275 (40): 31289–96. doi:10.1074/jbc.M004651200. ISSN 0021-9258. PMID 10875935.
Further reading
- Gallouzi IE, Steitz JA (2001). "Delineation of mRNA export pathways by the use of cell-permeable peptides". Science. 294 (5548): 1895–901. Bibcode:2001Sci...294.1895G. doi:10.1126/science.1064693. PMID 11729309.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Blanc V, Kennedy S, Davidson NO (2003). "A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling". J. Biol. Chem. 278 (42): 41198–204. doi:10.1074/jbc.M302951200. PMID 12896982.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Güttinger S, Mühlhäusser P, Koller-Eichhorn R, et al. (2004). "Transportin2 functions as importin and mediates nuclear import of HuR". Proc. Natl. Acad. Sci. U.S.A. 101 (9): 2918–23. Bibcode:2004PNAS..101.2918G. doi:10.1073/pnas.0400342101. PMC 365720. PMID 14981248.
- Rebane A, Aab A, Steitz JA (2004). "Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR". RNA. 10 (4): 590–9. doi:10.1261/rna.5224304. PMC 1370549. PMID 15037768.
- Lee BJ, Cansizoglu AE, Süel KE, et al. (2006). "Rules for nuclear localization sequence recognition by karyopherin beta 2". Cell. 126 (3): 543–58. doi:10.1016/j.cell.2006.05.049. PMC 3442361. PMID 16901787.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
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