FCER1G: Difference between revisions

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{{Infobox_gene}}
{{Infobox_gene}}
'''Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide''' is a [[protein]] that in humans is encoded by the FCER1G [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | url = https://www.ncbi.nlm.nih.gov/gene/2207 }}</ref>


'''Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide''' is a [[protein]] that in humans is encoded by the FCER1G [[gene]].
== Function ==
<ref name="entrez">
{{cite web
| title = Entrez Gene: Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
| url = https://www.ncbi.nlm.nih.gov/gene/2207
| accessdate = 2013-12-30 <!-- T13:41:06.479039-08:00 -->
}}</ref>
 
==Function==


The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008].
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008].


== References ==
== References ==
{{reflist}}
{{reflist}}


== Further reading ==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
*{{Cite journal  
* {{cite journal | vauthors = Tsuji M, Ezumi Y, Arai M, Takayama H | title = A novel association of Fc receptor gamma-chain with glycoprotein VI and their co-expression as a collagen receptor in human platelets | journal = The Journal of Biological Chemistry | volume = 272 | issue = 38 | pages = 23528–31 | date = September 1997 | pmid = 9295288 | doi = 10.1074/jbc.272.38.23528 }}
| doi = 10.1074/jbc.272.38.23528
* {{cite journal | vauthors = Kihara H, Siraganian RP | title = Src homology 2 domains of Syk and Lyn bind to tyrosine-phosphorylated subunits of the high affinity IgE receptor | journal = The Journal of Biological Chemistry | volume = 269 | issue = 35 | pages = 22427–32 | date = September 1994 | pmid = 8071371 }}
| last1 = Tsuji | first1 = M.
* {{cite journal | vauthors = Huang L, Chen S, Zha X, Yang L, Li B, Yu Z, Wang L, Li Y | title = Expression feature of CD3, FcεRIγ, and Zap-70 in patients with chronic lymphocytic leukemia | journal = Hematology | volume = 17 | issue = 2 | pages = 71–5 | date = March 2012 | pmid = 22664044 | pmc = | doi = 10.1179/102453312X13221316477895 }}
| last2 = Ezumi | first2 = Y.
* {{cite journal | vauthors = Kim YK, Park HW, Yang JS, Oh SY, Chang YS, Shin ES, Lee JE, Kim S, Gho YS, Cho SH, Min KU, Kim YY | title = Association and functional relevance of E237G, a polymorphism of the high-affinity immunoglobulin E-receptor beta chain gene, to airway hyper-responsiveness | journal = Clinical and Experimental Allergy | volume = 37 | issue = 4 | pages = 592–8 | date = April 2007 | pmid = 17430357 | pmc = | doi = 10.1111/j.1365-2222.2007.02680.x }}
| last3 = Arai | first3 = M.
* {{cite journal | vauthors = Zha X, Yan X, Shen Q, Zhang Y, Wu X, Chen S, Li B, Yang L, Geng S, Weng J, Du X, Li Y | title = Alternative expression of TCRζ related genes in patients with chronic myeloid leukemia | journal = Journal of Hematology & Oncology | volume = 5 | pages = 74 | date = December 2012 | pmid = 23228155 | pmc = 3544630 | doi = 10.1186/1756-8722-5-74 }}
| last4 = Takayama | first4 = H.
* {{cite journal | vauthors = Takahashi K, Hayashi N, Shimokawa T, Umehara N, Kaminogawa S, Ra C | title = Cooperative regulation of Fc receptor gamma-chain gene expression by multiple transcription factors, including Sp1, GABP, and Elf-1 | journal = The Journal of Biological Chemistry | volume = 283 | issue = 22 | pages = 15134–41 | date = May 2008 | pmid = 18378679 | pmc = 3258888 | doi = 10.1074/jbc.M800498200 }}
| title = A novel association of Fc receptor gamma-chain with glycoprotein VI and their co-expression as a collagen receptor in human platelets  
* {{cite journal | vauthors = Bao M, Hanabuchi S, Facchinetti V, Du Q, Bover L, Plumas J, Chaperot L, Cao W, Qin J, Sun SC, Liu YJ | title = CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase Cbl | journal = Journal of Immunology | volume = 189 | issue = 2 | pages = 786–92 | date = July 2012 | pmid = 22706086 | pmc = 3665352 | doi = 10.4049/jimmunol.1200887 }}
| journal = The Journal of Biological Chemistry  
* {{cite journal | vauthors = Gross BS, Melford SK, Watson SP | title = Evidence that phospholipase C-gamma2 interacts with SLP-76, Syk, Lyn, LAT and the Fc receptor gamma-chain after stimulation of the collagen receptor glycoprotein VI in human platelets | journal = European Journal of Biochemistry | volume = 263 | issue = 3 | pages = 612–23 | date = August 1999 | pmid = 10469124 | doi = 10.1046/j.1432-1327.1999.00560.x }}
| volume = 272  
* {{cite journal | vauthors = Kumar P, Singh B, Lal R, Rembhotkar GW, Singh AB | title = Association between reduced levels of total serum IgE and FcepsilonRI expression in non-releaser basophils | journal = Immunobiology | volume = 214 | issue = 5 | pages = 377–83 | year = 2009 | pmid = 19362683 | pmc = | doi = 10.1016/j.imbio.2008.09.008 }}
| issue = 38  
| pages = 23528–23531
| year = 1997  
| pmid = 9295288
}}
*{{Cite journal  
| last1 = Kihara | first1 = H.
| last2 = Siraganian | first2 = R. P.
| title = Src homology 2 domains of Syk and Lyn bind to tyrosine-phosphorylated subunits of the high affinity IgE receptor  
| journal = The Journal of Biological Chemistry  
| volume = 269  
| issue = 35  
| pages = 22427–22432
| year = 1994  
| pmid = 8071371
}}
*{{Cite journal  
| last1 = Huang | first1 = L.
| last2 = Chen | first2 = S.
| last3 = Zha | first3 = X.
| last4 = Yang | first4 = L.
| last5 = Li | first5 = B.
| last6 = Yu | first6 = Z.
| last7 = Wang | first7 = L.
| last8 = Li | first8 = Y.
| title = Expression feature of CD3, FcεRIγ, and Zap-70 in patients with chronic lymphocytic leukemia  
| doi = 10.1179/102453312X13221316477895
| journal = Hematology  
| volume = 17  
| issue = 2  
| pages = 71–75
| year = 2012  
| pmid = 22664044  
| pmc =  
}}
*{{Cite journal  
| last1 = Kim | first1 = Y. -K.
| last2 = Park | first2 = H. -W.
| last3 = Yang | first3 = J. -S.
| last4 = Oh | first4 = S. -Y.
| last5 = Chang | first5 = Y. -S.
| last6 = Shin | first6 = E. -S.
| last7 = Lee | first7 = J. -E.
| last8 = Kim | first8 = S.
| last9 = Gho | first9 = Y. S.
| last10 = Cho | first10 = S. -H.
| last11 = Min | first11 = K. -U.
| last12 = Kim | first12 = Y. -Y.
| doi = 10.1111/j.1365-2222.2007.02680.x
| title = Association and functional relevance of E237G, a polymorphism of the high-affinity immunoglobulin E-receptor ? Chain gene, to airway hyper-responsiveness  
| journal = Clinical & Experimental Allergy  
| volume = 37  
| issue = 4  
| pages = 592–598
| year = 2007  
| pmid = 17430357  
| pmc =  
}}
*{{Cite journal  
| last1 = Zha | first1 = X.
| last2 = Yan | first2 = X.
| last3 = Shen | first3 = Q.
| last4 = Zhang | first4 = Y.
| last5 = Wu | first5 = X.
| last6 = Chen | first6 = S.
| last7 = Li | first7 = B.
| last8 = Yang | first8 = L.
| last9 = Geng | first9 = S.
| last10 = Weng | first10 = J.
| last11 = Du | first11 = X.
| last12 = Li | first12 = Y.
| title = Alternative expression of TCRζ related genes in patients with chronic myeloid leukemia  
| doi = 10.1186/1756-8722-5-74
| journal = Journal of Hematology & Oncology  
| volume = 5  
| pages = 74  
| year = 2012  
| pmid = 23228155  
| pmc =3544630  
}}
*{{Cite journal  
| last1 = Takahashi | first1 = K.
| last2 = Hayashi | first2 = N.
| last3 = Shimokawa | first3 = T.
| last4 = Umehara | first4 = N.
| last5 = Kaminogawa | first5 = S.
| last6 = Ra | first6 = C.
| doi = 10.1074/jbc.M800498200
| title = Cooperative Regulation of Fc Receptor  -Chain Gene Expression by Multiple Transcription Factors, Including Sp1, GABP, and Elf-1  
| journal = Journal of Biological Chemistry  
| volume = 283  
| issue = 22  
| pages = 15134–15141
| year = 2008  
| pmid = 18378679  
| pmc =3258888  
}}
*{{Cite journal  
| last1 = Bao | first1 = M.
| last2 = Hanabuchi | first2 = S.
| last3 = Facchinetti | first3 = V.
| last4 = Du | first4 = Q.
| last5 = Bover | first5 = L.
| last6 = Plumas | first6 = J.
| last7 = Chaperot | first7 = L.
| last8 = Cao | first8 = W.
| last9 = Qin | first9 = J.
| last10 = Sun | first10 = S. -C.
| last11 = Liu | first11 = Y. -J.
| doi = 10.4049/jimmunol.1200887
| title = CD2AP/SHIP1 Complex Positively Regulates Plasmacytoid Dendritic Cell Receptor Signaling by Inhibiting the E3 Ubiquitin Ligase Cbl  
| journal = The Journal of Immunology  
| volume = 189  
| issue = 2  
| pages = 786–792
| year = 2012  
| pmid = 22706086  
| pmc =3665352  
}}
*{{Cite journal
| doi = 10.1046/j.1432-1327.1999.00560.x
| last1 = Gross | first1 = B. S.
| last2 = Melford | first2 = S. K.
| last3 = Watson | first3 = S. P.
| title = Evidence that phospholipase C-gamma2 interacts with SLP-76, Syk, Lyn, LAT and the Fc receptor gamma-chain after stimulation of the collagen receptor glycoprotein VI in human platelets  
| journal = European Journal of Biochemistry / FEBS
| volume = 263  
| issue = 3  
| pages = 612–623
| year = 1999  
| pmid = 10469124
}}
*{{Cite journal  
| last1 = Kumar | first1 = P.
| last2 = Singh | first2 = B.
| last3 = Lal | first3 = R.
| last4 = Rembhotkar | first4 = G. W.
| last5 = Singh | first5 = A. B.
| title = Association between reduced levels of total serum IgE and FcεRI expression in non-releaser basophils  
| doi = 10.1016/j.imbio.2008.09.008
| journal = Immunobiology  
| volume = 214  
| issue = 5  
| pages = 377–383
| year = 2009  
| pmid = 19362683  
| pmc =  
}}
 
{{refend}}
{{refend}}


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[[Category:Genes on human chromosome 1]]
[[Category:Genes on human chromosome 1]]


{{gene-1-stub}}
{{gene-1-stub}}

Latest revision as of 20:08, 20 January 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide is a protein that in humans is encoded by the FCER1G gene.[1]

Function

The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008].

References

  1. ↑ "Entrez Gene: Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Retrieved from "https://www.wikidoc.org/index.php?title=FCER1G&oldid=1530319"