HIST2H2AC: Difference between revisions

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'''Histone H2A type 2-C''' is a [[protein]] that in humans is encoded by the ''HIST2H2AC'' [[gene]].<ref name="pmid1469070">{{cite journal |vauthors=Collart D, Romain PL, Huebner K, Pockwinse S, Pilapil S, Cannizzaro LA, Lian JB, Croce CM, Stein JL, Stein GS | title = A human histone H2B.1 variant gene, located on chromosome 1, utilizes alternative 3' end processing | journal = J Cell Biochem | volume = 50 | issue = 4 | pages = 374–85 |date=Jan 1993 | pmid = 1469070 | pmc =  | doi = 10.1002/jcb.240500406 }}</ref><ref name="pmid9439656">{{cite journal |vauthors=Albig W, Doenecke D | title = The human histone gene cluster at the D6S105 locus | journal = Hum Genet | volume = 101 | issue = 3 | pages = 284–94 |date=Feb 1998 | pmid = 9439656 | pmc =  | doi =10.1007/s004390050630  }}</ref><ref name="pmid12408966">{{cite journal |vauthors=Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ | title = The human and mouse replication-dependent histone genes | journal = Genomics | volume = 80 | issue = 5 | pages = 487–98 |date=Oct 2002 | pmid = 12408966 | pmc =  | doi =10.1016/S0888-7543(02)96850-3  }}</ref><ref name="entrez"/>
'''Histone H2A type 2-C''' is a [[protein]] that in humans is encoded by the ''HIST2H2AC'' [[gene]].<ref name="pmid1469070">{{cite journal |vauthors=Collart D, Romain PL, Huebner K, Pockwinse S, Pilapil S, Cannizzaro LA, Lian JB, Croce CM, Stein JL, Stein GS | title = A human histone H2B.1 variant gene, located on chromosome 1, utilizes alternative 3' end processing | journal = J Cell Biochem | volume = 50 | issue = 4 | pages = 374–85 |date=Jan 1993 | pmid = 1469070 | pmc =  | doi = 10.1002/jcb.240500406 }}</ref><ref name="pmid9439656">{{cite journal |vauthors=Albig W, Doenecke D | title = The human histone gene cluster at the D6S105 locus | journal = Hum Genet | volume = 101 | issue = 3 | pages = 284–94 |date=Feb 1998 | pmid = 9439656 | pmc =  | doi =10.1007/s004390050630  }}</ref><ref name="pmid12408966">{{cite journal |vauthors=Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ | title = The human and mouse replication-dependent histone genes | journal = Genomics | volume = 80 | issue = 5 | pages = 487–98 |date=Oct 2002 | pmid = 12408966 | pmc =  | doi =10.1016/S0888-7543(02)96850-3  }}</ref><ref name="entrez"/>
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{{PBB_Summary
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| summary_text = Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order      structures. This gene is intronless and encodes a member of the histone H2A family.<ref name="entrez">{{cite web | title = Entrez Gene: HIST2H2AC histone cluster 2, H2ac| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8338| accessdate = }}</ref>
| summary_text = [[Histones]] are basic [[nuclear proteins]] that are responsible for the [[nucleosome]] structure of the chromosomal fiber in [[eukaryotes]]. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an [[octamer]], around which approximately 146 bp of [[DNA]] is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of [[chromatin]] into higher order      structures. This gene is intronless and encodes a member of the histone H2A family.<ref name="entrez">{{cite web | title = Entrez Gene: HIST2H2AC histone cluster 2, H2ac| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8338| accessdate = }}</ref>
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Latest revision as of 19:50, 22 February 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Histone H2A type 2-C is a protein that in humans is encoded by the HIST2H2AC gene.[1][2][3][4]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.[4]

References

  1. Collart D, Romain PL, Huebner K, Pockwinse S, Pilapil S, Cannizzaro LA, Lian JB, Croce CM, Stein JL, Stein GS (Jan 1993). "A human histone H2B.1 variant gene, located on chromosome 1, utilizes alternative 3' end processing". J Cell Biochem. 50 (4): 374–85. doi:10.1002/jcb.240500406. PMID 1469070.
  2. Albig W, Doenecke D (Feb 1998). "The human histone gene cluster at the D6S105 locus". Hum Genet. 101 (3): 284–94. doi:10.1007/s004390050630. PMID 9439656.
  3. Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). "The human and mouse replication-dependent histone genes". Genomics. 80 (5): 487–98. doi:10.1016/S0888-7543(02)96850-3. PMID 12408966.
  4. 4.0 4.1 "Entrez Gene: HIST2H2AC histone cluster 2, H2ac".

Further reading