EPS8L3: Difference between revisions
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'''Epidermal growth factor receptor kinase substrate 8-like protein 3''' is an [[enzyme]] that in humans is encoded by the ''EPS8L3'' [[gene]].<ref name="pmid12620401">{{cite journal | vauthors = Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C | title = In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure | journal = Genomics | volume = 81 | issue = 2 | pages = 234–44 |date=Mar 2003 | pmid = 12620401 | pmc = | doi =10.1016/S0888-7543(03)00002-8 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EPS8L3 EPS8-like 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79574| accessdate = }}</ref> | '''Epidermal growth factor receptor kinase substrate 8-like protein 3''' is an [[enzyme]] that in humans is encoded by the ''EPS8L3'' [[gene]].<ref name="pmid12620401">{{cite journal | vauthors = Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C | title = In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure | journal = Genomics | volume = 81 | issue = 2 | pages = 234–44 |date=Mar 2003 | pmid = 12620401 | pmc = | doi =10.1016/S0888-7543(03)00002-8 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EPS8L3 EPS8-like 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79574| accessdate = }}</ref> | ||
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| summary_text = This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist.<ref name="entrez">{{cite web | title = Entrez Gene: EPS8L3 EPS8-like 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79574| accessdate = }}</ref> | | summary_text = This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 ([[EPS8]]), a substrate for the [[epidermal growth factor receptor]]. The function of this protein is unknown. Alternatively spliced [[transcript variants]] encoding different [[isoforms]] exist.<ref name="entrez">{{cite web | title = Entrez Gene: EPS8L3 EPS8-like 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79574| accessdate = }}</ref> | ||
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Latest revision as of 17:24, 21 February 2018
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Epidermal growth factor receptor kinase substrate 8-like protein 3 is an enzyme that in humans is encoded by the EPS8L3 gene.[1][2]
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist.[2]
References
- ↑ Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C (Mar 2003). "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure". Genomics. 81 (2): 234–44. doi:10.1016/S0888-7543(03)00002-8. PMID 12620401.
- ↑ 2.0 2.1 "Entrez Gene: EPS8L3 EPS8-like 3".
Further reading
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Offenhäuser N, Borgonovo A, Disanza A, et al. (2004). "The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway". Mol. Biol. Cell. 15 (1): 91–8. doi:10.1091/mbc.E03-06-0427. PMC 307530. PMID 14565974.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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