Tau tubulin kinase 1: Difference between revisions
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{{Infobox_gene}} | {{Infobox_gene}} | ||
'''Tau tubulin kinase 1''' is a [[protein]] that in | '''Tau tubulin kinase 1''' is a [[protein]] that in [[human]]s is encoded by the TTBK1 [[gene]]. | ||
<ref name="entrez"> | <ref name="entrez"> | ||
{{cite web | {{cite web | ||
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| accessdate = 2017-03-23 | | accessdate = 2017-03-23 | ||
}}</ref> | }}</ref> | ||
== References == | == References == | ||
{{reflist}} | {{reflist}} | ||
== Further reading == | == Further reading == | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
*{{cite journal |vauthors=Sato S, Xu J, Okuyama S, Martinez LB, Walsh SM, Jacobsen MT, Swan RJ, Schlautman JD, Ciborowski P, Ikezu T |title=Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1 |journal=J. Neurosci. |volume=28 |issue=53 |pages=14511–21 |year=2008 |pmid=19118186 |doi=10.1523/JNEUROSCI.3417-08.2008 |url=}} | *{{cite journal |vauthors=Sato S, Xu J, Okuyama S, Martinez LB, Walsh SM, Jacobsen MT, Swan RJ, Schlautman JD, Ciborowski P, Ikezu T |title=Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1 |journal=J. Neurosci. |volume=28 |issue=53 |pages=14511–21 |year=2008 |pmid=19118186 |doi=10.1523/JNEUROSCI.3417-08.2008 |url=}} | ||
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*{{cite journal |vauthors=Yu NN, Yu JT, Xiao JT, Zhang HW, Lu RC, Jiang H, Xing ZH, Tan L |title=Tau-tubulin kinase-1 gene variants are associated with Alzheimer's disease in Han Chinese |journal=Neurosci. Lett. |volume=491 |issue=1 |pages=83–6 |year=2011 |pmid=21219968 |doi=10.1016/j.neulet.2011.01.011 |url=}} | *{{cite journal |vauthors=Yu NN, Yu JT, Xiao JT, Zhang HW, Lu RC, Jiang H, Xing ZH, Tan L |title=Tau-tubulin kinase-1 gene variants are associated with Alzheimer's disease in Han Chinese |journal=Neurosci. Lett. |volume=491 |issue=1 |pages=83–6 |year=2011 |pmid=21219968 |doi=10.1016/j.neulet.2011.01.011 |url=}} | ||
*{{cite journal |vauthors=Lund H, Cowburn RF, Gustafsson E, Strömberg K, Svensson A, Dahllund L, Malinowsky D, Sunnemark D |title=Tau-tubulin kinase 1 expression, phosphorylation and co-localization with phospho-Ser422 tau in the Alzheimer's disease brain |journal=Brain Pathol. |volume=23 |issue=4 |pages=378–89 |year=2013 |pmid=23088643 |doi=10.1111/bpa.12001 |url=}} | *{{cite journal |vauthors=Lund H, Cowburn RF, Gustafsson E, Strömberg K, Svensson A, Dahllund L, Malinowsky D, Sunnemark D |title=Tau-tubulin kinase 1 expression, phosphorylation and co-localization with phospho-Ser422 tau in the Alzheimer's disease brain |journal=Brain Pathol. |volume=23 |issue=4 |pages=378–89 |year=2013 |pmid=23088643 |doi=10.1111/bpa.12001 |url=}} | ||
*{{cite journal |vauthors=Kiefer SE, Chang CJ, Kimura SR, Gao M, Xie D, Zhang Y, Zhang G, Gill MB, Mastalerz H, Thompson LA, Cacace AM, Sheriff S |title=The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor |journal=Acta Crystallogr F | *{{cite journal |vauthors=Kiefer SE, Chang CJ, Kimura SR, Gao M, Xie D, Zhang Y, Zhang G, Gill MB, Mastalerz H, Thompson LA, Cacace AM, Sheriff S |title=The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor |journal=Acta Crystallogr F |volume=70 |issue=Pt 2 |pages=173–81 |year=2014 |pmid=24637750 |pmc=3936456 |doi=10.1107/S2053230X14000144 |url=}} | ||
{{refend}} | {{refend}} |
Latest revision as of 07:51, 14 October 2018
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External IDs | GeneCards: [1] | ||||||
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Species | Human | Mouse | |||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
Wikidata | |||||||
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Tau tubulin kinase 1 is a protein that in humans is encoded by the TTBK1 gene. [1]
References
- ↑ "Entrez Gene: Tau tubulin kinase 1". Retrieved 2017-03-23.
Further reading
- Sato S, Xu J, Okuyama S, Martinez LB, Walsh SM, Jacobsen MT, Swan RJ, Schlautman JD, Ciborowski P, Ikezu T (2008). "Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1". J. Neurosci. 28 (53): 14511–21. doi:10.1523/JNEUROSCI.3417-08.2008. PMID 19118186.
- Vázquez-Higuera JL, Martínez-García A, Sánchez-Juan P, Rodríguez-Rodríguez E, Mateo I, Pozueta A, Frank A, Valdivieso F, Berciano J, Bullido MJ, Combarros O (2011). "Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort". Neurobiol. Aging. 32 (3): 550.e5–9. doi:10.1016/j.neurobiolaging.2009.12.021. PMID 20096481.
- Vázquez-Higuera JL, Martínez-García A, Sánchez-Juan P, Rodríguez-Rodríguez E, Mateo I, Pozueta A, Frank A, Valdivieso F, Berciano J, Bullido MJ, Combarros O (2011). "Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort". Neurobiol. Aging. 32 (3): 550.e5–9. doi:10.1016/j.neurobiolaging.2009.12.021. PMID 20096481.
- Yu NN, Yu JT, Xiao JT, Zhang HW, Lu RC, Jiang H, Xing ZH, Tan L (2011). "Tau-tubulin kinase-1 gene variants are associated with Alzheimer's disease in Han Chinese". Neurosci. Lett. 491 (1): 83–6. doi:10.1016/j.neulet.2011.01.011. PMID 21219968.
- Lund H, Cowburn RF, Gustafsson E, Strömberg K, Svensson A, Dahllund L, Malinowsky D, Sunnemark D (2013). "Tau-tubulin kinase 1 expression, phosphorylation and co-localization with phospho-Ser422 tau in the Alzheimer's disease brain". Brain Pathol. 23 (4): 378–89. doi:10.1111/bpa.12001. PMID 23088643.
- Kiefer SE, Chang CJ, Kimura SR, Gao M, Xie D, Zhang Y, Zhang G, Gill MB, Mastalerz H, Thompson LA, Cacace AM, Sheriff S (2014). "The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor". Acta Crystallogr F. 70 (Pt 2): 173–81. doi:10.1107/S2053230X14000144. PMC 3936456. PMID 24637750.
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