HIST1H3I: Difference between revisions

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{{Infobox_gene}}
{{Infobox_gene}}
'''Histone H3.1''' is a [[protein]] that in humans is encoded by the ''HIST1H3I'' [[gene]].<ref name="pmid9031620">{{cite journal |vauthors=Albig W, Meergans T, Doenecke D | title = Characterization of the H1.5 gene completes the set of human H1 subtype genes | journal = Gene | volume = 184 | issue = 2 | pages = 141–8 |date=Mar 1997 | pmid = 9031620 | pmc =  | doi =10.1016/S0378-1119(96)00582-3 }}</ref><ref name="pmid9439656">{{cite journal |vauthors=Albig W, Doenecke D | title = The human histone gene cluster at the D6S105 locus | journal = Hum Genet | volume = 101 | issue = 3 | pages = 284–94 |date=Feb 1998 | pmid = 9439656 | pmc =  | doi =10.1007/s004390050630 }}</ref><ref name="pmid12408966">{{cite journal |vauthors=Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ | title = The human and mouse replication-dependent histone genes | journal = Genomics | volume = 80 | issue = 5 | pages = 487–98 |date=Oct 2002 | pmid = 12408966 | pmc =  | doi =10.1016/S0888-7543(02)96850-3 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: HIST1H3I histone cluster 1, H3i| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8354| accessdate = }}</ref>
'''Histone H3.1''' is a [[protein]] that in humans is encoded by the ''HIST1H3I'' [[gene]].<ref name="pmid9031620">{{cite journal | vauthors = Albig W, Meergans T, Doenecke D | title = Characterization of the H1.5 gene completes the set of human H1 subtype genes | journal = Gene | volume = 184 | issue = 2 | pages = 141–8 | date = January 1997 | pmid = 9031620 | pmc =  | doi = 10.1016/S0378-1119(96)00582-3 }}</ref><ref name="pmid9439656">{{cite journal | vauthors = Albig W, Doenecke D | title = The human histone gene cluster at the D6S105 locus | journal = Human Genetics | volume = 101 | issue = 3 | pages = 284–94 | date = December 1997 | pmid = 9439656 | pmc =  | doi = 10.1007/s004390050630 }}</ref><ref name="pmid12408966">{{cite journal | vauthors = Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ | title = The human and mouse replication-dependent histone genes | journal = Genomics | volume = 80 | issue = 5 | pages = 487–98 | date = November 2002 | pmid = 12408966 | pmc =  | doi = 10.1016/S0888-7543(02)96850-3 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: HIST1H3I histone cluster 1, H3i| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8354| access-date = }}</ref>


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== Function ==
{{PBB_Summary
| section_title =  
| summary_text = Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.<ref name="entrez" />
}}


==References==
[[Histone]]s are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in [[eukaryote]]s. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called [[nucleosome]]s. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of [[chromatin]] into higher order structures. This gene is [[intron]]less and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.<ref name="entrez" />
 
== References ==
{{reflist}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Lusic M, Marcello A, Cereseto A, Giacca M | title = Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter | journal = The EMBO Journal | volume = 22 | issue = 24 | pages = 6550–61 | date = December 2003 | pmid = 14657027 | pmc = 291826 | doi = 10.1093/emboj/cdg631 }}
| citations =
* {{cite journal | vauthors = Deng L, Wang D, de la Fuente C, Wang L, Li H, Lee CG, Donnelly R, Wade JD, Lambert P, Kashanchi F | title = Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA | journal = Virology | volume = 289 | issue = 2 | pages = 312–26 | date = October 2001 | pmid = 11689053 | doi = 10.1006/viro.2001.1129 }}
*{{cite journal |vauthors=Lusic M, Marcello A, Cereseto A, Giacca M |title=Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. |journal=EMBO J. |volume=22 |issue= 24 |pages= 6550–61 |year= 2004 |pmid= 14657027 |doi= 10.1093/emboj/cdg631 | pmc=291826 }}
* {{cite journal | vauthors = Deng L, de la Fuente C, Fu P, Wang L, Donnelly R, Wade JD, Lambert P, Li H, Lee CG, Kashanchi F | title = Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones | journal = Virology | volume = 277 | issue = 2 | pages = 278–95 | date = November 2000 | pmid = 11080476 | doi = 10.1006/viro.2000.0593 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
* {{cite journal | vauthors = El Kharroubi A, Piras G, Zensen R, Martin MA | title = Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter | journal = Molecular and Cellular Biology | volume = 18 | issue = 5 | pages = 2535–44 | date = May 1998 | pmid = 9566873 | pmc = 110633 | doi = 10.1128/mcb.18.5.2535 }}
*{{cite journal  |vauthors=Deng L, Wang D, de la Fuente C, etal |title=Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA. |journal=Virology |volume=289 |issue= 2 |pages= 312–26 |year= 2001 |pmid= 11689053 |doi= 10.1006/viro.2001.1129 }}
*{{cite journal   |vauthors=Deng L, de la Fuente C, Fu P, etal |title=Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. |journal=Virology |volume=277 |issue= 2 |pages= 278–95 |year= 2001 |pmid= 11080476 |doi= 10.1006/viro.2000.0593 }}
*{{cite journal |vauthors=El Kharroubi A, Piras G, Zensen R, Martin MA |title=Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. |journal=Mol. Cell. Biol. |volume=18 |issue= 5 |pages= 2535–44 |year= 1998 |pmid= 9566873 |doi= 10.1128/mcb.18.5.2535| pmc=110633  }}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=8354}}
{{PDB Gallery|geneid=8354}}
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Latest revision as of 20:22, 16 September 2018

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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Wikidata
View/Edit Human

Histone H3.1 is a protein that in humans is encoded by the HIST1H3I gene.[1][2][3][4]

Function

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.[4]

References

  1. ↑ Albig W, Meergans T, Doenecke D (January 1997). "Characterization of the H1.5 gene completes the set of human H1 subtype genes". Gene. 184 (2): 141–8. doi:10.1016/S0378-1119(96)00582-3. PMID 9031620.
  2. ↑ Albig W, Doenecke D (December 1997). "The human histone gene cluster at the D6S105 locus". Human Genetics. 101 (3): 284–94. doi:10.1007/s004390050630. PMID 9439656.
  3. ↑ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (November 2002). "The human and mouse replication-dependent histone genes". Genomics. 80 (5): 487–98. doi:10.1016/S0888-7543(02)96850-3. PMID 12408966.
  4. ↑ 4.0 4.1 "Entrez Gene: HIST1H3I histone cluster 1, H3i".

Further reading

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