Complement receptor of the immunoglobulin family: Difference between revisions
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'''Complement receptor of the immunoglobulin family''' is a [[protein]] expressed in [[Kupffer cell]]s.<ref>{{cite journal | vauthors = Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M | title = CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens | '''Complement receptor of the immunoglobulin family''' is a [[protein]] expressed in [[Kupffer cell]]s.<ref>{{cite journal | vauthors = Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M | title = CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens | journal = Cell | volume = 124 | issue = 5 | pages = 915–27 | year = 2006 | pmid = 16530040 | doi = 10.1016/j.cell.2005.12.039}}</ref>It is a critical receptor for the [[phagocytosis]] of [[Opsonin|opsonised]] particles in the [[blood]]. It recognizes [[iC3b]] (inactivated C3b) deposited on microbial surfaces. | ||
==See also== | ==See also== |
Latest revision as of 22:30, 5 September 2018
V-set and immunoglobulin domain containing 4 | |
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Identifiers | |
Symbol | VSIG4 |
Entrez | 11326 |
HUGO | 17032 |
OMIM | 300353 |
RefSeq | NM_007268 |
UniProt | Q9Y279 |
Other data | |
Locus | Chr. X q12-q13.3 |
Complement receptor of the immunoglobulin family is a protein expressed in Kupffer cells.[1]It is a critical receptor for the phagocytosis of opsonised particles in the blood. It recognizes iC3b (inactivated C3b) deposited on microbial surfaces.
See also
References
- ↑ Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M (2006). "CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens". Cell. 124 (5): 915–27. doi:10.1016/j.cell.2005.12.039. PMID 16530040.
This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it. |