Pleomorphic adenoma natural history, complications and prognosis: Difference between revisions
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===Prognosis=== | ===Prognosis=== | ||
*Prognosis is generally excellent | *Prognosis is generally excellent for most of the patients after surgical resection. | ||
*Depending on the extent of the | *Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary sometimes. | ||
*Recurrence can be a problem if the tumor arises from the parotid gland.<ref name="pmid9578257">{{cite journal |vauthors=Laskawi R, Schott T, Schröder M |title=Recurrent pleomorphic adenomas of the parotid gland: clinical evaluation and long-term follow-up |journal=Br J Oral Maxillofac Surg |volume=36 |issue=1 |pages=48–51 |date=February 1998 |pmid=9578257 |doi= |url=}}</ref><ref name="WittekindtStreubel2007">{{cite journal|last1=Wittekindt|first1=Claus|last2=Streubel|first2=Kristina|last3=Arnold|first3=Georg|last4=Stennert|first4=Eberhard|last5=Guntinas-Lichius|first5=Orlando|title=Recurrent pleomorphic adenoma of the parotid gland: Analysis of 108 consecutive patients|journal=Head & Neck|volume=29|issue=9|year=2007|pages=822–828|issn=10433074|doi=10.1002/hed.20613}}</ref> | |||
* | |||
*2-7% of cases can go into malignant transformation if left untreated.<ref name="SaidCampana2005">{{cite journal|last1=Said|first1=Sherif|last2=Campana|first2=John|title=Myoepithelial carcinoma ex pleomorphic adenoma of salivary glands: A problematic diagnosis|journal=Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology|volume=99|issue=2|year=2005|pages=196–201|issn=10792104|doi=10.1016/j.tripleo.2003.11.014}}</ref> | |||
==References== | ==References== | ||
Revision as of 15:07, 11 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- Pleomorphic adenoma usually presents as an asymptomatic disease.
- If symptomatic it presents as a slow growing, painless and a palpable single nodular mass.
- If left untreated patients with Pleomorphic adenoma may progress to malignant transformation.
Complications
Prognosis
- Prognosis is generally excellent for most of the patients after surgical resection.
- Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary sometimes.
- Recurrence can be a problem if the tumor arises from the parotid gland.[1][2]
- 2-7% of cases can go into malignant transformation if left untreated.[3]
References
- ↑ Laskawi R, Schott T, Schröder M (February 1998). "Recurrent pleomorphic adenomas of the parotid gland: clinical evaluation and long-term follow-up". Br J Oral Maxillofac Surg. 36 (1): 48–51. PMID 9578257.
- ↑ Wittekindt, Claus; Streubel, Kristina; Arnold, Georg; Stennert, Eberhard; Guntinas-Lichius, Orlando (2007). "Recurrent pleomorphic adenoma of the parotid gland: Analysis of 108 consecutive patients". Head & Neck. 29 (9): 822–828. doi:10.1002/hed.20613. ISSN 1043-3074.
- ↑ Said, Sherif; Campana, John (2005). "Myoepithelial carcinoma ex pleomorphic adenoma of salivary glands: A problematic diagnosis". Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 99 (2): 196–201. doi:10.1016/j.tripleo.2003.11.014. ISSN 1079-2104.