Astrocytoma history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
==History and Symptoms== | ==History and Symptoms== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
History and Symptoms
History
Patients with astrocytoma may have a positive history of:
- Exposure to:[1]
- Vinyl chloride
- Phenols
- Organic solvents
- Pesticides
- Formaldehyde
- Lubricating fluids
- Polycyclic aromatic hydrocarbons
- Past radiation therapy to the brain[2]
- Genetic Disorders such as:[3][4][5]
- Neurofibromatosis
- Tuberous sclerosis
- Li-Fraumeni syndrome
- Nevoid basal cell carcinoma syndrome
- Turcot syndrome
- Melanoma-astrocytoma syndrome
- Blood group A[6][7]
- Previous head trauma[8]
- Meningitis
- Epilepsy[7]
- Headache
- Limb parasthesia or weakness
- Difficulty swallowing
- Nausea
- Diplopia
- Lethargy
- Personality changes
- Blurred vision[9][10][11]
Common Symptoms
Common symptoms of astrocytoma are:[9][10][11]
- Morning headache or headache that goes away after vomiting
- Nausea and vomiting
- Vision, hearing, and speech problems
- Loss of balance and trouble walking
- Worsening handwriting or slow speech
- Weakness or change in feeling on one side of the body
- Unusual sleepiness
- Change in personality or behavior
- Increase in the size of the head (in infants)
- Seizures- In almost half of the cases, the first symptom of an astrocytoma is the onset of a focal or generalized seizure. Between 60 to 75% of patients will have recurrent seizures in the course of their illness.
- Children with astrocytoma usually have decreased memory, attention, and motor abilities, but unaffected intelligence, language, and academic skills.
- Anaplastic astrocytoma is often related to seizures, neurologic deficits, headaches, or changes in mental status.
Less Common Symptoms
Less common symptoms of astrocytoma include:
- Weight loss or weight gain for no known reason
- More or less energy than usual
NOTE: High grade tumors mostly cause local neurological deficit rather than seizure.
References
- ↑ Caporalini C, Buccoliero AM, Scoccianti S, Moscardi S, Simoni A, Pansini L, Bordi L, Ammannati F, Taddei GL (2016). "Granular cell astrocytoma: report of a case and review of the literature". Clin. Neuropathol. 35 (4): 186–93. doi:10.5414/NP300952. PMID 27125869.
- ↑ Sheppard JP, Nguyen T, Alkhalid Y, Beckett JS, Salamon N, Yang I (April 2018). "Risk of Brain Tumor Induction from Pediatric Head CT Procedures: A Systematic Literature Review". Brain Tumor Res Treat. 6 (1): 1–7. doi:10.14791/btrt.2018.6.e4. PMC 5932294. PMID 29717567.
- ↑ Soura E, Eliades PJ, Shannon K, Stratigos AJ, Tsao H (March 2016). "Hereditary melanoma: Update on syndromes and management: Genetics of familial atypical multiple mole melanoma syndrome". J. Am. Acad. Dermatol. 74 (3): 395–407, quiz 408–10. doi:10.1016/j.jaad.2015.08.038. PMC 4761105. PMID 26892650.
- ↑ Chourmouzi D, Papadopoulou E, Konstantinidis M, Syrris V, Kouskouras K, Haritanti A, Karkavelas G, Drevelegas A (June 2014). "Manifestations of pilocytic astrocytoma: a pictorial review". Insights Imaging. 5 (3): 387–402. doi:10.1007/s13244-014-0328-2. PMC 4035491. PMID 24789122.
- ↑ Gajavelli S, Nakhla J, Nasser R, Yassari R, Weidenheim KM, Graber J (2016). "Ollier disease with anaplastic astrocytoma: A review of the literature and a unique case". Surg Neurol Int. 7 (Suppl 23): S607–11. doi:10.4103/2152-7806.189731. PMC 5025950. PMID 27656320.
- ↑ BUCKWALTER JA, TURNER JH, GAMBER HH, RATERMAN L, SOPER RT, KNOWLER LA (April 1959). "Psychoses, intracranial neoplasms, and genetics". AMA Arch Neurol Psychiatry. 81 (4): 480–5. PMID 13636517.
- ↑ 7.0 7.1 Schlehofer B, Blettner M, Becker N, Martinsohn C, Wahrendorf J (May 1992). "Medical risk factors and the development of brain tumors". Cancer. 69 (10): 2541–7. PMID 1568177.
- ↑ Hochberg F, Toniolo P, Cole P (November 1984). "Head trauma and seizures as risk factors of glioblastoma". Neurology. 34 (11): 1511–4. PMID 6493505.
- ↑ 9.0 9.1 JL Ater; et al. (1996). "Correlation of medical and neurosurgical events with neuropsychological status in children at diagnosis of astrocytoma: utilization of a neurological severity score". Journal of Child Neurology. 11 (6): 462–469. PMID 9120225.
- ↑ 10.0 10.1 JM Dewar, PJ Dady and V Balakrishnan (1985). "Metastatic astrocytoma". Australian and New Zealand Journal of Medicine. 15 (6): 745–747. PMID 3010926.
- ↑ 11.0 11.1 Bigner, D. D. (2006). Russell and Rubinstein's pathology of tumors of the nervous system. London New York, NY: Hodder Arnold Distributed in the United States of America by Oxford University Press. ISBN 978-0340810071.