Craniopharyngioma differential diagnosis: Difference between revisions
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==Differentiating Craniopharyngioma from other Diseases== | ==Differentiating Craniopharyngioma from other Diseases== | ||
Craniopharyngioma is a mass in the pituitary region. The common pituitary masses that can be confused with craniopharyngioma are following. | Craniopharyngioma is a mass in the pituitary region. The common pituitary masses that can be confused with craniopharyngioma are following.<ref name="pmid1260697">{{cite journal |vauthors=Petito CK, DeGirolami U, Earle KM |title=Craniopharyngiomas: a clinical and pathological review |journal=Cancer |volume=37 |issue=4 |pages=1944–52 |date=April 1976 |pmid=1260697 |doi= |url=}}</ref> | ||
*[[Sarcoid]], sellar tumour ([[pituitary]] adenoma) | *[[Sarcoid]], sellar tumour ([[pituitary]] adenoma) | ||
*[[Aneurysm]] | *[[Aneurysm]] | ||
| Line 16: | Line 16: | ||
*[[Optic nerve glioma]] | *[[Optic nerve glioma]] | ||
General ''imaging differential'' considerations include: | General ''imaging differential'' considerations include:<ref name="pmid1260697">{{cite journal |vauthors=Petito CK, DeGirolami U, Earle KM |title=Craniopharyngiomas: a clinical and pathological review |journal=Cancer |volume=37 |issue=4 |pages=1944–52 |date=April 1976 |pmid=1260697 |doi= |url=}}</ref> | ||
*'''Rathke cleft cyst''' | *'''Rathke cleft cyst''' | ||
**No solid or enhancing component | **No solid or enhancing component | ||
| Line 29: | Line 29: | ||
**Presence of fat is helpful, but requires fat saturated sequences or CT to confirm | **Presence of fat is helpful, but requires fat saturated sequences or CT to confirm | ||
Craniopharyngioma must be differentiated from other causes of diabetes insipidus. | Craniopharyngioma must be differentiated from other causes of diabetes insipidus.<ref name="pmid1260697">{{cite journal |vauthors=Petito CK, DeGirolami U, Earle KM |title=Craniopharyngiomas: a clinical and pathological review |journal=Cancer |volume=37 |issue=4 |pages=1944–52 |date=April 1976 |pmid=1260697 |doi= |url=}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
!Type of DI | !Type of DI | ||
Revision as of 16:10, 14 January 2019
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Craniopharyngioma differential diagnosis On the Web |
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Risk calculators and risk factors for Craniopharyngioma differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]
Overview
Craniopharyngioma must be differentiated from other pituitary masses such as sarcoid, pituitary adenoma, aneurysm, teratoma, tuberculosis, rathke cleft cyst, chordoma, hypothalamic glioma, hamartoma of tuber cinereum, histiocytosis, meningioma and optic nerve glioma.
Differentiating Craniopharyngioma from other Diseases
Craniopharyngioma is a mass in the pituitary region. The common pituitary masses that can be confused with craniopharyngioma are following.[1]
- Sarcoid, sellar tumour (pituitary adenoma)
- Aneurysm
- Teratoma or tuberculosis (and other granulomatous diseases)
- Cleft cyst (Rathke), chordoma
- Hypothalamic glioma, hamartoma of tuber cinereum, histiocytosis
- Meningioma, metastasis
- Optic nerve glioma
General imaging differential considerations include:[1]
- Rathke cleft cyst
- No solid or enhancing component
- Calcification is rare
- Unilocular
- Majority are completely or mostly intrasellar
- Pituitary macroadenoma
- Can look very similar
- Usually has intrasellar epicentre with pituitary fossa enlargement rather than suprasellar epicentre
- Despite occasional presence of T1 bright cystic regions, calcification in these cases is often absent (whereas most adamantinomatous craniopharyngiomas are calcified)
- Intracranial teratoma
- Presence of fat is helpful, but requires fat saturated sequences or CT to confirm
Craniopharyngioma must be differentiated from other causes of diabetes insipidus.[1]
| Type of DI | Subclass | Disease | Defining signs and symptoms | Lab/Imaging findings |
|---|---|---|---|---|
| Central | Acquired | Histiocytosis |
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| Craniopharyngioma |
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| Sarcoidosis |
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| Congenital | Hydrocephalus |
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Dilated ventricles on CT and MRI
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| Wolfram Syndrome (DIDMOAD) |
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| Nephrogenic | Acquired | Drug-induced (demeclocycline, lithium) |
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| Hypercalcemia |
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| Hypokalemia |
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| Multiple myeloma |
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| Sickle cell disease |
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| Primary polydipsia | Psychogenic |
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| Gestational diabetes insipidus |
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| Diabetes mellitus |
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References
- ↑ 1.0 1.1 1.2 Petito CK, DeGirolami U, Earle KM (April 1976). "Craniopharyngiomas: a clinical and pathological review". Cancer. 37 (4): 1944–52. PMID 1260697.
- ↑ Ghosh KN, Bhattacharya A (1992). "Gonotrophic nature of Phlebotomus argentipes (Diptera: Psychodidae) in the laboratory". Rev Inst Med Trop Sao Paulo. 34 (2): 181–2. PMID 1340034.